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The map label for this gene is yfhA [H]

Identifier: 226224977

GI number: 226224977

Start: 2470621

End: 2471631

Strand: Reverse

Name: yfhA [H]

Synonym: Lm4b_02398

Alternate gene names: 226224977

Gene position: 2471631-2470621 (Counterclockwise)

Preceding gene: 226224978

Following gene: 226224976

Centisome position: 84.86

GC content: 45.2

Gene sequence:

>1011_bases
ATGACAACTGTGAAGGCGCATGATCCGCGGCGAAAACGTAGACGGATAACTTTTATTGTAGTAATCATTTTACTTATTTT
AGCTTTTTTCTACGGACTGACAACGGGGTCCGTGAAAATTACATATAGTGATGCTTGGCAGACGCTAACTGGCGGGGGAA
GTGACCTAGCGAACCAATTGATTTGGAACTTGCGCTTGCCGCGGTTATTAATTGCTTTCTTAGTAGGAGCAGCGCTGGCG
ATTGCTGGATGCTTGCTGCAAGGCGTGATGCGGAATCCATTAGCTGACCCAGGCGTAATTGGGGTTTCAGCCGGTGGTGG
CTTCGTGGCCATTTTAATGACATTAGCATTTCCTGCGTTAGCTTCCTTTGTGCCGATTGGTGCGTTTTTAGGGGCGTTTG
GAACAGCTATTTTGATTTATTTGCTTGCATGGGATCGCGGTGTTTCTCCTTTACGTGTAATTTTGTCTGGGGTGGCGATT
AATGCGTTTATTGGTGCGATGACGTCTGGCGTAATGGTGCTTTATAGCAACCGGGTTCAAAGTGTTATTTCTTGGATGAC
AGGGACACTTTCCGGAAAAAGTTGGTATCATTTGGATATGATTTGGCCGTATATGCTGGTCGGGTTTGTTTTAAGTGGTT
TTGCGATTCGTTCTTCTAATGTATTGCTACTTGGGGATGATGCGGCGAAATTACTTGGCTTTTCTGTGGAACGGCATCGC
TTTTTTATTATAATGTTGGCGGCCTTTCTCAGTGGGGTTGCGGTTAGTGTAGCTGGACTTATTGGCTTTGTTGGACTTGT
TGTGCCACATATTTTCCGTTTGATCATTGGAAATGACTATAAATACTTACTGCCACTATCCGCACTCGGCGGGGCTTTAT
TAGTTGGCTTTGCTGATACAGCAGCTAGAAGTTGGTTCGGATCCATCGAGCTTCCTGTTGGAATCCTACTTGCAATGATA
GGCGCACCATTCTTCTTATTCTTACTTCAAAGAGGGAGGGTTGCTTCATGA

Upstream 100 bases:

>100_bases
TTGTCGTACTTCCTGCAGAGCTATTCGGAACAAATCCTGGAATTAAGATTGATCAAGCATTGGATTATATGACAGATGAG
ATAAATAAGGTGGATAACTA

Downstream 100 bases:

>100_bases
AATCAGCATTAGAACTAAAAAATGTTTCTTTCTCACGTAAAAGAGATTTCGAAATGAAAAACGTGAGCGCGAGTATTCCA
GAAGGGAAAATCACTACGCT

Product: ferrichrome ABC transporter (permease) FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTTVKAHDPRRKRRRITFIVVIILLILAFFYGLTTGSVKITYSDAWQTLTGGGSDLANQLIWNLRLPRLLIAFLVGAALA
IAGCLLQGVMRNPLADPGVIGVSAGGGFVAILMTLAFPALASFVPIGAFLGAFGTAILIYLLAWDRGVSPLRVILSGVAI
NAFIGAMTSGVMVLYSNRVQSVISWMTGTLSGKSWYHLDMIWPYMLVGFVLSGFAIRSSNVLLLGDDAAKLLGFSVERHR
FFIIMLAAFLSGVAVSVAGLIGFVGLVVPHIFRLIIGNDYKYLLPLSALGGALLVGFADTAARSWFGSIELPVGILLAMI
GAPFFLFLLQRGRVAS

Sequences:

>Translated_336_residues
MTTVKAHDPRRKRRRITFIVVIILLILAFFYGLTTGSVKITYSDAWQTLTGGGSDLANQLIWNLRLPRLLIAFLVGAALA
IAGCLLQGVMRNPLADPGVIGVSAGGGFVAILMTLAFPALASFVPIGAFLGAFGTAILIYLLAWDRGVSPLRVILSGVAI
NAFIGAMTSGVMVLYSNRVQSVISWMTGTLSGKSWYHLDMIWPYMLVGFVLSGFAIRSSNVLLLGDDAAKLLGFSVERHR
FFIIMLAAFLSGVAVSVAGLIGFVGLVVPHIFRLIIGNDYKYLLPLSALGGALLVGFADTAARSWFGSIELPVGILLAMI
GAPFFLFLLQRGRVAS
>Mature_335_residues
TTVKAHDPRRKRRRITFIVVIILLILAFFYGLTTGSVKITYSDAWQTLTGGGSDLANQLIWNLRLPRLLIAFLVGAALAI
AGCLLQGVMRNPLADPGVIGVSAGGGFVAILMTLAFPALASFVPIGAFLGAFGTAILIYLLAWDRGVSPLRVILSGVAIN
AFIGAMTSGVMVLYSNRVQSVISWMTGTLSGKSWYHLDMIWPYMLVGFVLSGFAIRSSNVLLLGDDAAKLLGFSVERHRF
FIIMLAAFLSGVAVSVAGLIGFVGLVVPHIFRLIIGNDYKYLLPLSALGGALLVGFADTAARSWFGSIELPVGILLAMIG
APFFLFLLQRGRVAS

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=270, Percent_Identity=42.2222222222222, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790741, Length=322, Percent_Identity=33.2298136645963, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786804, Length=326, Percent_Identity=31.5950920245399, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=37.5, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786805, Length=299, Percent_Identity=32.1070234113712, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786347, Length=317, Percent_Identity=31.5457413249211, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35927; Mature: 35795

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVKAHDPRRKRRRITFIVVIILLILAFFYGLTTGSVKITYSDAWQTLTGGGSDLANQL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCHHHHHHH
IWNLRLPRLLIAFLVGAALAIAGCLLQGVMRNPLADPGVIGVSAGGGFVAILMTLAFPAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
ASFVPIGAFLGAFGTAILIYLLAWDRGVSPLRVILSGVAINAFIGAMTSGVMVLYSNRVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVISWMTGTLSGKSWYHLDMIWPYMLVGFVLSGFAIRSSNVLLLGDDAAKLLGFSVERHR
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCEEECCCEEEECCCHHHHHCCHHHHHH
FFIIMLAAFLSGVAVSVAGLIGFVGLVVPHIFRLIIGNDYKYLLPLSALGGALLVGFADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHH
AARSWFGSIELPVGILLAMIGAPFFLFLLQRGRVAS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTVKAHDPRRKRRRITFIVVIILLILAFFYGLTTGSVKITYSDAWQTLTGGGSDLANQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCHHHHHHH
IWNLRLPRLLIAFLVGAALAIAGCLLQGVMRNPLADPGVIGVSAGGGFVAILMTLAFPAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
ASFVPIGAFLGAFGTAILIYLLAWDRGVSPLRVILSGVAINAFIGAMTSGVMVLYSNRVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVISWMTGTLSGKSWYHLDMIWPYMLVGFVLSGFAIRSSNVLLLGDDAAKLLGFSVERHR
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCEEECCCEEEECCCHHHHHCCHHHHHH
FFIIMLAAFLSGVAVSVAGLIGFVGLVVPHIFRLIIGNDYKYLLPLSALGGALLVGFADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHH
AARSWFGSIELPVGILLAMIGAPFFLFLLQRGRVAS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]