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The map label for this gene is glvA [H]

Identifier: 226224905

GI number: 226224905

Start: 2392174

End: 2393481

Strand: Reverse

Name: glvA [H]

Synonym: Lm4b_02324

Alternate gene names: 226224905

Gene position: 2393481-2392174 (Counterclockwise)

Preceding gene: 226224906

Following gene: 226224904

Centisome position: 82.17

GC content: 36.24

Gene sequence:

>1308_bases
ATGAAAAAACAAATTATTACTATTGCTGGCGGAGGAAGTACTTATACACCGGGAATCATTCAAGCTGTACTTAACGGGCA
AGAACGATTACCAGTAAGTGAAATCCGTTTGTATGATATTGAAGCAACAAGAAATGAAAATATGTATTTAATTCTGGATT
ATATGCTAGAACAACAAGGCTTTTCATCAATTAAATTAGTACAAACAACCAATCCTGAAGAAGCATTTACTGGGGCAGAC
TTTATCTTTTCGCAAATTCGCGTTGGCGGACTTAAAATGCGCGATAAAGATGAAAAAATCCCACTAAAGCATGGATTAGT
CGGACAAGAAACATGTGGACTTGGCGGATTTTCTTACGGTTTACGTAGTATTGGCCCACTGTTAGAATTAGTTGGCTTTA
TTCAAAAATATGCGCCAGAAGCTTGGATTTTAAATTATACGAACCCAGAAACGATTATTTCTGAAGCTGTACGAAGACAA
TTTCCTGGTATTCGAATGATTAATGTATGTGATATGACAATCGGAATTGAAGATACACTAGCTAAAAATTATGGCTATGA
CCGTGATAATTGGATTGCTACTTACTATGGTTTAAATCACTTTGGTTGGTATACGAAAATTTATGATAAGTCATTAAAAC
GTGATATTATGCCAGAGCTTTTAGAGAAGTTGAAAGTCCAAGAAATCAAAGAAGAAGACCCAAGTTGGAATCGCGCATTC
AATATGATACGCTTTATGGTTCAAAATTTTCCGGATAACTTGCCAAACAACTATTTAGAGTATTATTTGTATCCAGATAT
GTATGTCGATTACGCTGATCCAAATTATACCCGCGCGAATACAGTAATGGATGGTCGTGAGCAAAAAACACAAGAAATGG
CAGATAAAATCCGCAACAAAGAAAAAGGAGATGTGCTTGATTTCTACTTTGGTGTACACGGCTTATATATTGTAGACATA
GCTACTTCGCTACTAAATGATGAGAAAAGTCGCTTTATGTTAATCGTTGAAAACAAAGGATCCATCCCGAATTTACGTAG
TGATGCAGTTGTTGAAGTTCCAGCATACGTTGGTGCGACAGGTGTAGAAGCAATTGCCTTGCCTGCAATTGGTGATTTCC
ATAAAGGTATGATGGAAGCGCAAGTTGCTGCGGAGAAACTACTCGTAGATGCGTACTTTGAAAAATCTTATCAAAAAGCA
TTACAAGCATTTACATTAAATCAATCGGTTCCAAATGCCACAGTGGCGAAGAAAGTATTGGATGAAATGATGATTGAAAA
TAAAGCATTTTGGCCAGAATTAAAATAA

Upstream 100 bases:

>100_bases
TATGTAGAGCAAATAAGTGCATGTAGTACCTATCGCGAATGCGTGGAATTATTACAAACTATATATAATAACAACGAGTA
AGTTTGAAGGAGTGAGAGGT

Downstream 100 bases:

>100_bases
GTATCAAACATCGTATGACGGATGAAAGTTCGCTATACGATGTTTTTTGTTATCCAACCGGGCGCCTTCCCTGCAAAGAA
ATGCTATAATTAAACTATTA

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-alpha-D-glucosidase; 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYLILDYMLEQQGFSSIKLVQTTNPEEAFTGAD
FIFSQIRVGGLKMRDKDEKIPLKHGLVGQETCGLGGFSYGLRSIGPLLELVGFIQKYAPEAWILNYTNPETIISEAVRRQ
FPGIRMINVCDMTIGIEDTLAKNYGYDRDNWIATYYGLNHFGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAF
NMIRFMVQNFPDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNKEKGDVLDFYFGVHGLYIVDI
ATSLLNDEKSRFMLIVENKGSIPNLRSDAVVEVPAYVGATGVEAIALPAIGDFHKGMMEAQVAAEKLLVDAYFEKSYQKA
LQAFTLNQSVPNATVAKKVLDEMMIENKAFWPELK

Sequences:

>Translated_435_residues
MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYLILDYMLEQQGFSSIKLVQTTNPEEAFTGAD
FIFSQIRVGGLKMRDKDEKIPLKHGLVGQETCGLGGFSYGLRSIGPLLELVGFIQKYAPEAWILNYTNPETIISEAVRRQ
FPGIRMINVCDMTIGIEDTLAKNYGYDRDNWIATYYGLNHFGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAF
NMIRFMVQNFPDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNKEKGDVLDFYFGVHGLYIVDI
ATSLLNDEKSRFMLIVENKGSIPNLRSDAVVEVPAYVGATGVEAIALPAIGDFHKGMMEAQVAAEKLLVDAYFEKSYQKA
LQAFTLNQSVPNATVAKKVLDEMMIENKAFWPELK
>Mature_435_residues
MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYLILDYMLEQQGFSSIKLVQTTNPEEAFTGAD
FIFSQIRVGGLKMRDKDEKIPLKHGLVGQETCGLGGFSYGLRSIGPLLELVGFIQKYAPEAWILNYTNPETIISEAVRRQ
FPGIRMINVCDMTIGIEDTLAKNYGYDRDNWIATYYGLNHFGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAF
NMIRFMVQNFPDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNKEKGDVLDFYFGVHGLYIVDI
ATSLLNDEKSRFMLIVENKGSIPNLRSDAVVEVPAYVGATGVEAIALPAIGDFHKGMMEAQVAAEKLLVDAYFEKSYQKA
LQAFTLNQSVPNATVAKKVLDEMMIENKAFWPELK

Specific function: Hydrolyzes maltose-6'-phosphate and trehalose-6'- phosphate. Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent maltose phosphotransferase system (PEP-PTS). Is also able to significantly catalyze the hydrolys

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=453, Percent_Identity=28.476821192053, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1790560, Length=433, Percent_Identity=24.0184757505774, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.122 [H]

Molecular weight: Translated: 49591; Mature: 49591

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYLILDYMLEQQG
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCEEEEHHHHHHHCC
FSSIKLVQTTNPEEAFTGADFIFSQIRVGGLKMRDKDEKIPLKHGLVGQETCGLGGFSYG
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHCCCCCCCCCCCCCHHHH
LRSIGPLLELVGFIQKYAPEAWILNYTNPETIISEAVRRQFPGIRMINVCDMTIGIEDTL
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHH
AKNYGYDRDNWIATYYGLNHFGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAF
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NMIRFMVQNFPDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNK
HHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHCCC
EKGDVLDFYFGVHGLYIVDIATSLLNDEKSRFMLIVENKGSIPNLRSDAVVEVPAYVGAT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECHHHCCC
GVEAIALPAIGDFHKGMMEAQVAAEKLLVDAYFEKSYQKALQAFTLNQSVPNATVAKKVL
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DEMMIENKAFWPELK
HHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYLILDYMLEQQG
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCEEEEHHHHHHHCC
FSSIKLVQTTNPEEAFTGADFIFSQIRVGGLKMRDKDEKIPLKHGLVGQETCGLGGFSYG
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHCCCCCCCCCCCCCHHHH
LRSIGPLLELVGFIQKYAPEAWILNYTNPETIISEAVRRQFPGIRMINVCDMTIGIEDTL
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHH
AKNYGYDRDNWIATYYGLNHFGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAF
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NMIRFMVQNFPDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNK
HHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHCCC
EKGDVLDFYFGVHGLYIVDIATSLLNDEKSRFMLIVENKGSIPNLRSDAVVEVPAYVGAT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECHHHCCC
GVEAIALPAIGDFHKGMMEAQVAAEKLLVDAYFEKSYQKALQAFTLNQSVPNATVAKKVL
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DEMMIENKAFWPELK
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 9765262; 11489864; 10329789 [H]