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The map label for this gene is hit [H]

Identifier: 226224824

GI number: 226224824

Start: 2311123

End: 2311545

Strand: Direct

Name: hit [H]

Synonym: Lm4b_02243

Alternate gene names: 226224824

Gene position: 2311123-2311545 (Clockwise)

Preceding gene: 226224821

Following gene: 226224825

Centisome position: 79.35

GC content: 37.59

Gene sequence:

>423_bases
ATGGACGATTGCATTTTCTGCAAAATAGTTCGTGGCGAAATTCCTTCTGCCAAAGTGTATGAAGATGATGAAGTATATGC
TTTCCTCGATTTAGGCCAAGTTACAGAAGGTCATACACTCGTAATTCCCAAAAAACATGCTAGGAACACATTCGATTTAC
CCGATGAAACGGCCGCTGAATTATTCCGCCGCGTACCAAAAATCGCGCGGGCATTAAAAGAAGCTTTACCGATTCAAGGA
TTAAATATTTTAAATAATAATGAAGAAGTTGCTTTCCAATCTGTTTTTCATTGTCATATCCATTTAATACCAAGGTATAG
CAAATCAGACGACTTTGGGTTAAAATGGAAAGATAACGCAGACTGGTATACACAAGAACGTTACCAAGAAATTGCTGAAC
TTATTGCAGCAAAAGTAGACTAA

Upstream 100 bases:

>100_bases
AAATAATCCACCACCTACTATCTAACACATGCTTTTCACTGCTTTTTATGTTAAATTAAAATAGTACATAATTATATGTA
ATGAAAGGTGGTCATACTTA

Downstream 100 bases:

>100_bases
AATGACTTTATGGATGGAGTGGAGTATAAATGAATAAAAAATCACTTATTTTCGGTATTTTAGCTGGTGGGGCAATTGGA
GCCGCAGCCTCGGTATTATT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MDDCIFCKIVRGEIPSAKVYEDDEVYAFLDLGQVTEGHTLVIPKKHARNTFDLPDETAAELFRRVPKIARALKEALPIQG
LNILNNNEEVAFQSVFHCHIHLIPRYSKSDDFGLKWKDNADWYTQERYQEIAELIAAKVD

Sequences:

>Translated_140_residues
MDDCIFCKIVRGEIPSAKVYEDDEVYAFLDLGQVTEGHTLVIPKKHARNTFDLPDETAAELFRRVPKIARALKEALPIQG
LNILNNNEEVAFQSVFHCHIHLIPRYSKSDDFGLKWKDNADWYTQERYQEIAELIAAKVD
>Mature_140_residues
MDDCIFCKIVRGEIPSAKVYEDDEVYAFLDLGQVTEGHTLVIPKKHARNTFDLPDETAAELFRRVPKIARALKEALPIQG
LNILNNNEEVAFQSVFHCHIHLIPRYSKSDDFGLKWKDNADWYTQERYQEIAELIAAKVD

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17506713, Length=102, Percent_Identity=34.3137254901961, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=113, Percent_Identity=41.5929203539823, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 16134; Mature: 16134

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDCIFCKIVRGEIPSAKVYEDDEVYAFLDLGQVTEGHTLVIPKKHARNTFDLPDETAAE
CCCEEEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCEEEEECHHCCCCCCCCCHHHHH
LFRRVPKIARALKEALPIQGLNILNNNEEVAFQSVFHCHIHLIPRYSKSDDFGLKWKDNA
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHEEEEEEEECCCCCCCCCEEECCCC
DWYTQERYQEIAELIAAKVD
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDDCIFCKIVRGEIPSAKVYEDDEVYAFLDLGQVTEGHTLVIPKKHARNTFDLPDETAAE
CCCEEEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCEEEEECHHCCCCCCCCCHHHHH
LFRRVPKIARALKEALPIQGLNILNNNEEVAFQSVFHCHIHLIPRYSKSDDFGLKWKDNA
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHEEEEEEEECCCCCCCCCEEECCCC
DWYTQERYQEIAELIAAKVD
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]