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The map label for this gene is ahpF [C]

Identifier: 226224566

GI number: 226224566

Start: 2029671

End: 2030669

Strand: Direct

Name: ahpF [C]

Synonym: Lm4b_01980

Alternate gene names: 226224566

Gene position: 2029671-2030669 (Clockwise)

Preceding gene: 226224565

Following gene: 226224571

Centisome position: 69.68

GC content: 42.44

Gene sequence:

>999_bases
GTGCCAAATGAGGTTTATGATGTAACCATTATCGGCGGCGGTCCCATTGGCCTATTCTCCGCATTTTATAGTGGGCTTCG
TTCCATGAAAACAAAAATTATCGATGCTGAACCTGCTGTTGGCGGGAAAGTTCGCTACTTTTTTCCAGAAAAAATCATTC
GCGATATCGGTGGTATTCCCGCCATTACCGGCGAAAATCTTGTCGCAAATTTAAAACAACAAGCAGAAACCTTTCATCCG
ACTATTGTTTGCAGTGAGCGAGTTGTCGATGTGACAAAACTATCAGATGGCACTTTTCAATTAACTTCGCATAACGGTTC
GATCCATTTTTCAAAAACGATTGTCATTGCTACAGGTAGTGGCACGTTTGAGGTCAATAAACTTGAAGCTCTACATGCTG
AAGATTTTCCATTTGCAATCCATTATGATGTCAAAAATATCGAGCAATTCCGCGATAAAGTAGTAGTGGTTTCTGGTGGT
GGAAATTCCGCTATCGACTGGGCTCAGACACTCGAACCCATTGCCAAACAAGTACACCTTATTTACCGTGGCGAAGATTT
TAAAGCACACGAGGAAAGTGTCCGAGAACTTCAAAATTCTCGCGTCGAAATCCATATCCACCATGAAATCAATGAACTAA
TCGGAACAAACAATCAGTTAACCAAAATCAATGTTTGCTGCAATAAAACCCAAGCCACGAAAACAATTCAAACAGACGCA
CTTTTCATTAATCACGGGGTAAAAGTAGACCTTGGAACCATGGCGGAATGGGGCTTTGAACAAGCAGATTTTGGCATTGT
CGTGGATGACGAGATGAAAACGACGGTTCCTGGCATTTTCGCTTGTGGAGATAGTGCGACTTACCCTCGAAAAATACGCA
TTATCGCAGCGGGACTTCATGAAGGGCCCATCGCGATTAATAGTGCGAAAAAATATTTAGAACCAACTGCCGCAGATGAA
GCGATGATTAGCACGCATCACGAAAGCTTTATTGGTTAA

Upstream 100 bases:

>100_bases
ATCAAAGCAGATATTTTAATTGATCCCCGCAGCGGTGTCCCTCTTTGCCTCCCCTACGAAACTTGCAACGGATGCGAAAT
TGTAAAGGAGCTTGATTCCA

Downstream 100 bases:

>100_bases
AAAAAGGATTTGGGCTCACTCGCCCAAATCCTTTTTTTCTTCGCATATCCCAAATTCGACAATTCGCATCATTTCCGTAA
AATCCTTCGCAAGCGGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: FNR 1; Fd-NADP+ reductase 1 [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKQQAETFHP
TIVCSERVVDVTKLSDGTFQLTSHNGSIHFSKTIVIATGSGTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGG
GNSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELQNSRVEIHIHHEINELIGTNNQLTKINVCCNKTQATKTIQTDA
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLHEGPIAINSAKKYLEPTAADE
AMISTHHESFIG

Sequences:

>Translated_332_residues
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKQQAETFHP
TIVCSERVVDVTKLSDGTFQLTSHNGSIHFSKTIVIATGSGTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGG
GNSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELQNSRVEIHIHHEINELIGTNNQLTKINVCCNKTQATKTIQTDA
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLHEGPIAINSAKKYLEPTAADE
AMISTHHESFIG
>Mature_331_residues
PNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKQQAETFHPT
IVCSERVVDVTKLSDGTFQLTSHNGSIHFSKTIVIATGSGTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGGG
NSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELQNSRVEIHIHHEINELIGTNNQLTKINVCCNKTQATKTIQTDAL
FINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLHEGPIAINSAKKYLEPTAADEA
MISTHHESFIG

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=324, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787114, Length=333, Percent_Identity=24.9249249249249, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=24.8447204968944, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 36406; Mature: 36275

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIP
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECHHHHHHHCCCCC
AITGENLVANLKQQAETFHPTIVCSERVVDVTKLSDGTFQLTSHNGSIHFSKTIVIATGS
CCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEECCCEEEEEEEEEEEECC
GTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGGGNSAIDWAQTLEPIAKQVHL
CEEEEEEEEEECCCCCCEEEEECHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEE
IYRGEDFKAHEESVRELQNSRVEIHIHHEINELIGTNNQLTKINVCCNKTQATKTIQTDA
EEECCCCCHHHHHHHHHHCCEEEEEEEEEHHHHHCCCCCEEEEEEEECCCCCCEEEEECE
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLH
EEEECCCEEEECCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
EGPIAINSAKKYLEPTAADEAMISTHHESFIG
CCCEEECCHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIP
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECHHHHHHHCCCCC
AITGENLVANLKQQAETFHPTIVCSERVVDVTKLSDGTFQLTSHNGSIHFSKTIVIATGS
CCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEECCCEEEEEEEEEEEECC
GTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGGGNSAIDWAQTLEPIAKQVHL
CEEEEEEEEEECCCCCCEEEEECHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEE
IYRGEDFKAHEESVRELQNSRVEIHIHHEINELIGTNNQLTKINVCCNKTQATKTIQTDA
EEECCCCCHHHHHHHHHHCCEEEEEEEEEHHHHHCCCCCEEEEEEEECCCCCCEEEEECE
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLH
EEEECCCEEEECCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
EGPIAINSAKKYLEPTAADEAMISTHHESFIG
CCCEEECCHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]