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The map label for this gene is recU

Identifier: 226224495

GI number: 226224495

Start: 1951716

End: 1952321

Strand: Direct

Name: recU

Synonym: Lm4b_01908

Alternate gene names: 226224495

Gene position: 1951716-1952321 (Clockwise)

Preceding gene: 226224483

Following gene: 226224496

Centisome position: 67.01

GC content: 37.13

Gene sequence:

>606_bases
ATGGCTATTGGTTACCCTAACGGCAAGAAGTATGCAGCGAGTCATGAGGTTCTTCCTCAACAAAAACGGAAAGCTCCTGT
AACTTATGGTAAGCGTGGTATGTCTTTGGAAGATGACCTAAATGATACGATTGCGTATTATTTAACTCACGAAATAGCAG
TCATCCACAAAAAACCTACCCCTGTCCAAATTGTCAGTGTGGACTACCCAAAAAGAAGTAGTGCCAAAATTAAGGAAGCC
TACTTCAAAACACCATCCACAACAGATTATAATGGTGTGTATAAAGGAAAATACGTTGATTTTGAAGCAAAAGAAACGCA
AAATACAACTTCTTTTCCGTTGAGTAATTTTCACGATCACCAAATGACACACATGGCAAACGTCTTAAAACAAGATGGTA
TTGTATTTGTCATTATTGCTTTCCAAAAACTCGGAGAAACTCATTTCATTCCCTTTGAGAAATTTTATCCGTTTTGGGAA
CGTATGCAAAGTGGTGGAAGAAAATCAGTTACTATAGCAGAAATACAAGATGTATCAGACCAAATTCCTTATGGTCTAAA
TCCAAGGCTTGACTTCTTGCAATCCATAGACAAATTATACTTCTAG

Upstream 100 bases:

>100_bases
TATTTTGCATTTAATTGATACTATCATTTTCATTTTTATTTGTTATAATAGATGATAGTCTAAAATTCAGAATAGAAATT
TTCTGATAGAGGTGAAAAAA

Downstream 100 bases:

>100_bases
TCAAACCTTTTTTAAAGGAGAGAGATTTTTAATGGCAGATAAACCGCAGACAAGATCTCAGTATCGCAATAAACAAAGTG
GTGGTTCTAAAAAGAAATCC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAIGYPNGKKYAASHEVLPQQKRKAPVTYGKRGMSLEDDLNDTIAYYLTHEIAVIHKKPTPVQIVSVDYPKRSSAKIKEA
YFKTPSTTDYNGVYKGKYVDFEAKETQNTTSFPLSNFHDHQMTHMANVLKQDGIVFVIIAFQKLGETHFIPFEKFYPFWE
RMQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLQSIDKLYF

Sequences:

>Translated_201_residues
MAIGYPNGKKYAASHEVLPQQKRKAPVTYGKRGMSLEDDLNDTIAYYLTHEIAVIHKKPTPVQIVSVDYPKRSSAKIKEA
YFKTPSTTDYNGVYKGKYVDFEAKETQNTTSFPLSNFHDHQMTHMANVLKQDGIVFVIIAFQKLGETHFIPFEKFYPFWE
RMQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLQSIDKLYF
>Mature_200_residues
AIGYPNGKKYAASHEVLPQQKRKAPVTYGKRGMSLEDDLNDTIAYYLTHEIAVIHKKPTPVQIVSVDYPKRSSAKIKEAY
FKTPSTTDYNGVYKGKYVDFEAKETQNTTSFPLSNFHDHQMTHMANVLKQDGIVFVIIAFQKLGETHFIPFEKFYPFWER
MQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLQSIDKLYF

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004612
- InterPro:   IPR011335 [H]

Pfam domain/function: PF03838 RecU [H]

EC number: NA

Molecular weight: Translated: 23084; Mature: 22952

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGYPNGKKYAASHEVLPQQKRKAPVTYGKRGMSLEDDLNDTIAYYLTHEIAVIHKKPT
CCCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCC
PVQIVSVDYPKRSSAKIKEAYFKTPSTTDYNGVYKGKYVDFEAKETQNTTSFPLSNFHDH
CEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCEEECCCCCCCCCCCCCCCCCCCHH
QMTHMANVLKQDGIVFVIIAFQKLGETHFIPFEKFYPFWERMQSGGRKSVTIAEIQDVSD
HHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
QIPYGLNPRLDFLQSIDKLYF
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AIGYPNGKKYAASHEVLPQQKRKAPVTYGKRGMSLEDDLNDTIAYYLTHEIAVIHKKPT
CCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCC
PVQIVSVDYPKRSSAKIKEAYFKTPSTTDYNGVYKGKYVDFEAKETQNTTSFPLSNFHDH
CEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCEEECCCCCCCCCCCCCCCCCCCHH
QMTHMANVLKQDGIVFVIIAFQKLGETHFIPFEKFYPFWERMQSGGRKSVTIAEIQDVSD
HHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
QIPYGLNPRLDFLQSIDKLYF
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]