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The map label for this gene is bdlA [H]

Identifier: 226224302

GI number: 226224302

Start: 1750345

End: 1751247

Strand: Direct

Name: bdlA [H]

Synonym: Lm4b_01713

Alternate gene names: 226224302

Gene position: 1750345-1751247 (Clockwise)

Preceding gene: 226224300

Following gene: 226224303

Centisome position: 60.09

GC content: 39.42

Gene sequence:

>903_bases
ATGAATGTTAATGCGGAAACAGAAGACGCAACTCTCCTTCTCGATGGTTTACTTCAAAACGTGGCAATAATTCGTTTTGA
TACTAATAAAAAAGTAACTTATGCTAATGCCCTTTTCGCGGAGGCAATGGGATACTCAGAAGAAGAAATGTTGACTTTAT
CCCACCCGGACTTATGCTTTCCTGATCTTGTCCAAAGTGCAAGCTATAAAGCAATGTGGACAAATTTGCTTGCTGGGCAA
AAATTTCAAAATAAAATTGAACGAAAAAATGCACGCGGTGAACGTGTTTGGTTTGAAGCGACTTATATCCCGATTATACG
TGAAGATACGGTCGTTGGAGTAGCCAAAATCGCTACAGATATTACGAGAAGAGAAGAAACGGTTCATGACTTTGCATCTG
GTTTAAAAAGCATGGCTACAAATTTAAAAGAACATTCCAGTGTTGGAAAAACGCGCAGTGAAGCTCTCCTTGAACTCGTG
AAATCAATCACGAAAGAATCCAATGAAAATACCGATACACTTCACGATTTGCAAACAGAAGCCCAAAATATTCACGGCAT
TATTAATACAATTAACGGTATTGCTTCTCAGACTAATTTACTTGCCTTAAATGCAGCGATTGAGGCAGCACGTGCTGGTG
ACGCCGGACGTGGATTTAGTGTTGTAGCGGAAGAAGTTCGTAAACTTTCGAGTCGTGTAGAAGAAGCAATTAAAGAAGTG
GAAAAAAGTGTCAACGGTATCACGCAAGAAATTAATACTATCTCAAGTGGTACGGAACGTGTCGAAGCAAAAGTCGAGGA
AAGCCAAGAAGTGCTTATTTTATCTTTAGAAGACTTTAGCCAAATTGAATCTGCCTCTACTGCCTTGGATCAAAATGCCG
GTGCTTTCACAAAAATGATTTAA

Upstream 100 bases:

>100_bases
TTTTATTAAAAAATAAACTTTCCATTACGAATACATGTGTGTTATTATGTTGATGTTGGTTGTTTTTATATTATTTTTCT
AAAAAATGGAGGTTTTTTTA

Downstream 100 bases:

>100_bases
CCGACTGAAAAAAGGAGCGAAGAAACCTTGAAACTTATTGGAAAACATCCTTCTGGTCGTGCCATTATTATCCGTTTGAA
CAACCAAGAATACCATTATG

Product: hypothetical protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNVNAETEDATLLLDGLLQNVAIIRFDTNKKVTYANALFAEAMGYSEEEMLTLSHPDLCFPDLVQSASYKAMWTNLLAGQ
KFQNKIERKNARGERVWFEATYIPIIREDTVVGVAKIATDITRREETVHDFASGLKSMATNLKEHSSVGKTRSEALLELV
KSITKESNENTDTLHDLQTEAQNIHGIINTINGIASQTNLLALNAAIEAARAGDAGRGFSVVAEEVRKLSSRVEEAIKEV
EKSVNGITQEINTISSGTERVEAKVEESQEVLILSLEDFSQIESASTALDQNAGAFTKMI

Sequences:

>Translated_300_residues
MNVNAETEDATLLLDGLLQNVAIIRFDTNKKVTYANALFAEAMGYSEEEMLTLSHPDLCFPDLVQSASYKAMWTNLLAGQ
KFQNKIERKNARGERVWFEATYIPIIREDTVVGVAKIATDITRREETVHDFASGLKSMATNLKEHSSVGKTRSEALLELV
KSITKESNENTDTLHDLQTEAQNIHGIINTINGIASQTNLLALNAAIEAARAGDAGRGFSVVAEEVRKLSSRVEEAIKEV
EKSVNGITQEINTISSGTERVEAKVEESQEVLILSLEDFSQIESASTALDQNAGAFTKMI
>Mature_300_residues
MNVNAETEDATLLLDGLLQNVAIIRFDTNKKVTYANALFAEAMGYSEEEMLTLSHPDLCFPDLVQSASYKAMWTNLLAGQ
KFQNKIERKNARGERVWFEATYIPIIREDTVVGVAKIATDITRREETVHDFASGLKSMATNLKEHSSVGKTRSEALLELV
KSITKESNENTDTLHDLQTEAQNIHGIINTINGIASQTNLLALNAAIEAARAGDAGRGFSVVAEEVRKLSSRVEEAIKEV
EKSVNGITQEINTISSGTERVEAKVEESQEVLILSLEDFSQIESASTALDQNAGAFTKMI

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=83, Percent_Identity=56.6265060240964, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI2367378, Length=170, Percent_Identity=35.8823529411765, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788195, Length=81, Percent_Identity=50.6172839506173, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787690, Length=89, Percent_Identity=49.438202247191, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789453, Length=91, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 32937; Mature: 32937

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVNAETEDATLLLDGLLQNVAIIRFDTNKKVTYANALFAEAMGYSEEEMLTLSHPDLCF
CCCCCCCCHHHHHHHHHHHCEEEEEECCCCCEEHHHHHHHHHHCCCHHHEEEECCCCCCC
PDLVQSASYKAMWTNLLAGQKFQNKIERKNARGERVWFEATYIPIIREDTVVGVAKIATD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHHHH
ITRREETVHDFASGLKSMATNLKEHSSVGKTRSEALLELVKSITKESNENTDTLHDLQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AQNIHGIINTINGIASQTNLLALNAAIEAARAGDAGRGFSVVAEEVRKLSSRVEEAIKEV
HHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKSVNGITQEINTISSGTERVEAKVEESQEVLILSLEDFSQIESASTALDQNAGAFTKMI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MNVNAETEDATLLLDGLLQNVAIIRFDTNKKVTYANALFAEAMGYSEEEMLTLSHPDLCF
CCCCCCCCHHHHHHHHHHHCEEEEEECCCCCEEHHHHHHHHHHCCCHHHEEEECCCCCCC
PDLVQSASYKAMWTNLLAGQKFQNKIERKNARGERVWFEATYIPIIREDTVVGVAKIATD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHHHH
ITRREETVHDFASGLKSMATNLKEHSSVGKTRSEALLELVKSITKESNENTDTLHDLQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AQNIHGIINTINGIASQTNLLALNAAIEAARAGDAGRGFSVVAEEVRKLSSRVEEAIKEV
HHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKSVNGITQEINTISSGTERVEAKVEESQEVLILSLEDFSQIESASTALDQNAGAFTKMI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]