Click here to switch to the map view.

The map label for this gene is perR [H]

Identifier: 226224286

GI number: 226224286

Start: 1734672

End: 1735118

Strand: Reverse

Name: perR [H]

Synonym: Lm4b_01697

Alternate gene names: 226224286

Gene position: 1735118-1734672 (Counterclockwise)

Preceding gene: 226224287

Following gene: 226224285

Centisome position: 59.57

GC content: 36.24

Gene sequence:

>447_bases
ATGGCGGTGTCTAATGCAACTCTAAAAGAGGCAGTAGATGTCTTAAAGAAAACAGGAGTAAGAATCACTCCTCAGCGTCA
TGCTATACTTGAATTCTTAATTAACTCACATACACACCCAACCGCGGATGATATTTATCGGGCTTTAGAAGGAAACTTCC
CTAACATGAGCGTAGCAACTGTATATAATAATTTACGCGTTTTCCGGGATGCTGGTCTAATTAAAGAATTATCCTATGGC
GATGCATCTAGTCGATTTGATTTTTCTACATCTAATCATTACCACGCAATTTGTAATGTGTGTGGAAAAATAGTTGATTT
TCAATATCCAGGTTTAGATGAAGTAGAACATTTCGCAGCACATATGACCGGATATGAAATAGATAATCACAGACTGGAAG
TATATGGTATATGTCCAGCCTGTAAAGAAAAACAATCAAATAATTAA

Upstream 100 bases:

>100_bases
TTGAATAAAGGTTATTAAGCTATAAATTCTGCCATTCTATTGACAGTTAAGCGTTATTTCCGGTATTATAAAGATAATAA
TTATTTTTGGAAGGGAGTGC

Downstream 100 bases:

>100_bases
TCAAAACACTTAGCCTAGCTAGGTGTTTTTTTGTGTTTTTTGCAATTTTTTTCATTTTTATTTAATTTTATGCATAATTC
GGTTGACATATATCTCAAAA

Product: transcription regulator (Fur family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRALEGNFPNMSVATVYNNLRVFRDAGLIKELSYG
DASSRFDFSTSNHYHAICNVCGKIVDFQYPGLDEVEHFAAHMTGYEIDNHRLEVYGICPACKEKQSNN

Sequences:

>Translated_148_residues
MAVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRALEGNFPNMSVATVYNNLRVFRDAGLIKELSYG
DASSRFDFSTSNHYHAICNVCGKIVDFQYPGLDEVEHFAAHMTGYEIDNHRLEVYGICPACKEKQSNN
>Mature_147_residues
AVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRALEGNFPNMSVATVYNNLRVFRDAGLIKELSYGD
ASSRFDFSTSNHYHAICNVCGKIVDFQYPGLDEVEHFAAHMTGYEIDNHRLEVYGICPACKEKQSNN

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=32.5925925925926, Blast_Score=73, Evalue=6e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16621; Mature: 16490

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRALEGNFPNMSVAT
CCCCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHH
VYNNLRVFRDAGLIKELSYGDASSRFDFSTSNHYHAICNVCGKIVDFQYPGLDEVEHFAA
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
HMTGYEIDNHRLEVYGICPACKEKQSNN
HHCCCEECCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRALEGNFPNMSVAT
CCCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHH
VYNNLRVFRDAGLIKELSYGDASSRFDFSTSNHYHAICNVCGKIVDFQYPGLDEVEHFAA
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
HMTGYEIDNHRLEVYGICPACKEKQSNN
HHCCCEECCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]