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The map label for this gene is rsbRD [H]

Identifier: 226224243

GI number: 226224243

Start: 1671133

End: 1671936

Strand: Reverse

Name: rsbRD [H]

Synonym: Lm4b_01653

Alternate gene names: 226224243

Gene position: 1671936-1671133 (Counterclockwise)

Preceding gene: 226224244

Following gene: 226224242

Centisome position: 57.4

GC content: 33.96

Gene sequence:

>804_bases
ATGCAAATTAAGGAATTTTTGATTAGTCGTCGTTCAGAGTTAGTGAATATGTTTTATGAAAATTATTATAGTGAAACAGA
TGAATTTAAATTAAGACTTAGTAGCGGGGAAGAGGAAGCCTCCATTCGTGCGCTGAGTACCGCATCATGTGGGATGATTA
TTGATGTAATAACTGGTGTGAAGGAACGCGACTTTGAAAGTATCGGTAAGAGACGTTTCAATGATAAAACCGATATTAGA
AAAATCCATCAACATATGAGTGAAGTTGAAAAATACATCATTACTAGCTTAGTGAAGTGGAAGGAAGCAGAAAATGTTTT
CTATACGGATGCTGACATTATCAAATTTATGCTTGATATAAAAGATACGCTTTCATCCATTCAACAACAATTGTTAGAAG
GATTTATGCAAGAAAATAGAAATCAAGTAGCAGCTCAGCGAAAAGAAATCATTCAATTATCCACGCGAATTATTCCAATA
AATGATTCTATTGGCGTTTTACCAATTGTTGGTAGTTTAGATGACGATAGAGGTTATTTTATGAAAGAAAAAGCAGTAGA
ATCTGCGGATAAGCTGAATTTAGATACGATTGTCATTGATTTTTCCAGTGCGGTATTAAAAGATGATTTTGCAACCAAAC
ATATGGAAGATATGATTCAATCTTTTAAATTAATTGGCTTAGTACCAATACTGTCTGGTATGCGTCCGAGTTTCGCTCAA
CGCACAATCCAAGTAGGTTCTAACATTTCAAAACTCGAATCATTTGGCTCGCTAGAACAAGCATTAACCAATTTAGGTTT
ATAA

Upstream 100 bases:

>100_bases
TTGATTTAACAGCGGAACAAGTGGATAAAATGATTGAAAATTTACATGCAGATAACATCTTAATTTTTGCAAGATAATAT
CGGTGAAAAAGGAGAAGTTT

Downstream 100 bases:

>100_bases
AATACAGATGAATGGCACTCCGTTGTCATTCATTTTTTGCTATAAGAAAAAGTTATCGAATTATAGCGGATTCTCTTTGT
TTACTTATCGCCCGTTTTTA

Product: sigma factor regulator

Products: NA

Alternate protein names: Stressosome protein rsbRD [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MQIKEFLISRRSELVNMFYENYYSETDEFKLRLSSGEEEASIRALSTASCGMIIDVITGVKERDFESIGKRRFNDKTDIR
KIHQHMSEVEKYIITSLVKWKEAENVFYTDADIIKFMLDIKDTLSSIQQQLLEGFMQENRNQVAAQRKEIIQLSTRIIPI
NDSIGVLPIVGSLDDDRGYFMKEKAVESADKLNLDTIVIDFSSAVLKDDFATKHMEDMIQSFKLIGLVPILSGMRPSFAQ
RTIQVGSNISKLESFGSLEQALTNLGL

Sequences:

>Translated_267_residues
MQIKEFLISRRSELVNMFYENYYSETDEFKLRLSSGEEEASIRALSTASCGMIIDVITGVKERDFESIGKRRFNDKTDIR
KIHQHMSEVEKYIITSLVKWKEAENVFYTDADIIKFMLDIKDTLSSIQQQLLEGFMQENRNQVAAQRKEIIQLSTRIIPI
NDSIGVLPIVGSLDDDRGYFMKEKAVESADKLNLDTIVIDFSSAVLKDDFATKHMEDMIQSFKLIGLVPILSGMRPSFAQ
RTIQVGSNISKLESFGSLEQALTNLGL
>Mature_267_residues
MQIKEFLISRRSELVNMFYENYYSETDEFKLRLSSGEEEASIRALSTASCGMIIDVITGVKERDFESIGKRRFNDKTDIR
KIHQHMSEVEKYIITSLVKWKEAENVFYTDADIIKFMLDIKDTLSSIQQQLLEGFMQENRNQVAAQRKEIIQLSTRIIPI
NDSIGVLPIVGSLDDDRGYFMKEKAVESADKLNLDTIVIDFSSAVLKDDFATKHMEDMIQSFKLIGLVPILSGMRPSFAQ
RTIQVGSNISKLESFGSLEQALTNLGL

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30443; Mature: 30443

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKEFLISRRSELVNMFYENYYSETDEFKLRLSSGEEEASIRALSTASCGMIIDVITGV
CCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCC
KERDFESIGKRRFNDKTDIRKIHQHMSEVEKYIITSLVKWKEAENVFYTDADIIKFMLDI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
KDTLSSIQQQLLEGFMQENRNQVAAQRKEIIQLSTRIIPINDSIGVLPIVGSLDDDRGYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCHH
MKEKAVESADKLNLDTIVIDFSSAVLKDDFATKHMEDMIQSFKLIGLVPILSGMRPSFAQ
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RTIQVGSNISKLESFGSLEQALTNLGL
HHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQIKEFLISRRSELVNMFYENYYSETDEFKLRLSSGEEEASIRALSTASCGMIIDVITGV
CCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCC
KERDFESIGKRRFNDKTDIRKIHQHMSEVEKYIITSLVKWKEAENVFYTDADIIKFMLDI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
KDTLSSIQQQLLEGFMQENRNQVAAQRKEIIQLSTRIIPINDSIGVLPIVGSLDDDRGYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCHH
MKEKAVESADKLNLDTIVIDFSSAVLKDDFATKHMEDMIQSFKLIGLVPILSGMRPSFAQ
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RTIQVGSNISKLESFGSLEQALTNLGL
HHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946 [H]