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The map label for this gene is mreD

Identifier: 226224147

GI number: 226224147

Start: 1563981

End: 1564499

Strand: Reverse

Name: mreD

Synonym: Lm4b_01557

Alternate gene names: 226224147

Gene position: 1564499-1563981 (Counterclockwise)

Preceding gene: 226224148

Following gene: 226224146

Centisome position: 53.71

GC content: 30.64

Gene sequence:

>519_bases
ATGAACGTTAAGAAAAACATTGCACTTCCTGCAATCATGGTTGGAACCTTTATTCTTGAGGGTGTTTTTAGTCTTCAGTT
TGCGAATGGTCTGTTTAATGATAGACATCTTTTTATTCCACATTTTTTACTTATTATGTTGACGATTATGACTTGTTTTT
ATAAACGAAATACGACTTTAGCATATGCTTTTATTCTAGGCTTGCTGTTTGATATTTATTATACTGGCGTGATGGGCATT
TATTTTGCTATCTTCCCGTTTACAGTGTATATCACAGATAAATTTATGAAAGTGTTGCAAAATAATATACTTTTGGTTGG
GTTAATTGCGATATTTAATATTATTCTTACAGAAAGTTTAGTATATGCGTTTTATTATTTGATTGGTACGACAACCATGT
CTATCCCAGTTTTTATTGATCAGCGTTTATGGACAACCATTTTGATTAATTTAGCATTCTTTTTAGTTGTCTTTTTCCCA
TTCCGATTGTTTCTTGATCGTTTGGTTAAATCAGAATAA

Upstream 100 bases:

>100_bases
TGTATGATCTAAATCATGTTACTGTGTTGAAGCGTTCAGCGGAAGCAGGGACAACGGATGACGATACAACTAGTTCAGAC
ACGACTGGAGGACAATAATC

Downstream 100 bases:

>100_bases
CTATCGTAATTTTAACAGTTTGAAGTCGCTATTACTTGAAAAAGTATGACTGTGGAGAATATCCACAGTTTGCGATTTCA
AGCTGTTTTTTCAAAAAAAG

Product: cell-shape determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNVKKNIALPAIMVGTFILEGVFSLQFANGLFNDRHLFIPHFLLIMLTIMTCFYKRNTTLAYAFILGLLFDIYYTGVMGI
YFAIFPFTVYITDKFMKVLQNNILLVGLIAIFNIILTESLVYAFYYLIGTTTMSIPVFIDQRLWTTILINLAFFLVVFFP
FRLFLDRLVKSE

Sequences:

>Translated_172_residues
MNVKKNIALPAIMVGTFILEGVFSLQFANGLFNDRHLFIPHFLLIMLTIMTCFYKRNTTLAYAFILGLLFDIYYTGVMGI
YFAIFPFTVYITDKFMKVLQNNILLVGLIAIFNIILTESLVYAFYYLIGTTTMSIPVFIDQRLWTTILINLAFFLVVFFP
FRLFLDRLVKSE
>Mature_172_residues
MNVKKNIALPAIMVGTFILEGVFSLQFANGLFNDRHLFIPHFLLIMLTIMTCFYKRNTTLAYAFILGLLFDIYYTGVMGI
YFAIFPFTVYITDKFMKVLQNNILLVGLIAIFNIILTESLVYAFYYLIGTTTMSIPVFIDQRLWTTILINLAFFLVVFFP
FRLFLDRLVKSE

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 19984; Mature: 19984

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKKNIALPAIMVGTFILEGVFSLQFANGLFNDRHLFIPHFLLIMLTIMTCFYKRNTTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
AYAFILGLLFDIYYTGVMGIYFAIFPFTVYITDKFMKVLQNNILLVGLIAIFNIILTESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VYAFYYLIGTTTMSIPVFIDQRLWTTILINLAFFLVVFFPFRLFLDRLVKSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVKKNIALPAIMVGTFILEGVFSLQFANGLFNDRHLFIPHFLLIMLTIMTCFYKRNTTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
AYAFILGLLFDIYYTGVMGIYFAIFPFTVYITDKFMKVLQNNILLVGLIAIFNIILTESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VYAFYYLIGTTTMSIPVFIDQRLWTTILINLAFFLVVFFPFRLFLDRLVKSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]