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The map label for this gene is zurR

Identifier: 226224046

GI number: 226224046

Start: 1461761

End: 1462186

Strand: Reverse

Name: zurR

Synonym: Lm4b_01455

Alternate gene names: 226224046

Gene position: 1462186-1461761 (Counterclockwise)

Preceding gene: 226224047

Following gene: 226224045

Centisome position: 50.2

GC content: 35.45

Gene sequence:

>426_bases
ATGGGACTTACAGCAACTGAAGCACTCATGAAAATGAAGGAAAAAGGCTATAAACACACAGATAAACGTGAATTTCTAAT
TAACTTACTAGCGAGGAAAAATAAATATTTGACGGCGAAAGATGTCTTAGAAAATATGAAAGATGATTTCCCGGGAATAA
GTTTTGATACGATTTACCGCAATCTCTCTTTATTTGTAGAATTAGGTATTTTTGAAGAAACAGATCTTTCTGGTGAACGC
AATTTCCGTTTAGCTTGTACACACGAGCATCACCATCATCATTTTATTTGCATGAAATGTGGGAAAACAAAAGAAATTAT
GATGTGCCCAATGGATTTTTTAACCGAAGCTTTACCCGGTTACCAAATTGACGGTCATAAATTCGAGGTTTACGGCGAAT
GTCCAGAATGTTTACAAGCCTCTTAA

Upstream 100 bases:

>100_bases
GGTGGAGCCATCGTTATTATATCCGTGCTACTTTTAATCGTCACCATTTTATATCAAAAAATACGTCAAAAAATCTTAAT
TTCAAAACGAGGTGAGGAAA

Downstream 100 bases:

>100_bases
TAGCAAAAGGTCCGAATTCCGGGCCTTTTTTATTTTATGCGTAATGTTCACAGTTATTTCATATTTGTTTCTTATTCTGG
ACACTTTTTATCGCTAAAGT

Product: transcriptional regulator ZurR (ferric uptake regulation)

Products: NA

Alternate protein names: Zinc uptake regulator

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MGLTATEALMKMKEKGYKHTDKREFLINLLARKNKYLTAKDVLENMKDDFPGISFDTIYRNLSLFVELGIFEETDLSGER
NFRLACTHEHHHHHFICMKCGKTKEIMMCPMDFLTEALPGYQIDGHKFEVYGECPECLQAS

Sequences:

>Translated_141_residues
MGLTATEALMKMKEKGYKHTDKREFLINLLARKNKYLTAKDVLENMKDDFPGISFDTIYRNLSLFVELGIFEETDLSGER
NFRLACTHEHHHHHFICMKCGKTKEIMMCPMDFLTEALPGYQIDGHKFEVYGECPECLQAS
>Mature_140_residues
GLTATEALMKMKEKGYKHTDKREFLINLLARKNKYLTAKDVLENMKDDFPGISFDTIYRNLSLFVELGIFEETDLSGERN
FRLACTHEHHHHHFICMKCGKTKEIMMCPMDFLTEALPGYQIDGHKFEVYGECPECLQAS

Specific function: Probably required for the zinc-specific repression of the operon zuRMA implicated in zinc uptake

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): ZURR_LISIN (P0A3E7)

Other databases:

- EMBL:   AL596168
- PIR:   AB1618
- RefSeq:   NP_470819.1
- ProteinModelPortal:   P0A3E7
- SMR:   P0A3E7
- GeneID:   1130088
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin1483
- GenoList:   LIN1483
- HOGENOM:   HBG731501
- OMA:   HEVEEWA
- ProtClustDB:   CLSK2461553
- BioCyc:   LINN272626:LIN1483-MONOMER
- GO:   GO:0005737
- InterPro:   IPR002481

Pfam domain/function: PF01475 FUR

EC number: NA

Molecular weight: Translated: 16371; Mature: 16240

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
9.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTATEALMKMKEKGYKHTDKREFLINLLARKNKYLTAKDVLENMKDDFPGISFDTIYR
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHH
NLSLFVELGIFEETDLSGERNFRLACTHEHHHHHFICMKCGKTKEIMMCPMDFLTEALPG
HHHHEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEEECCHHHHHHHCCC
YQIDGHKFEVYGECPECLQAS
CEECCCEEEEECCCCHHHCCC
>Mature Secondary Structure 
GLTATEALMKMKEKGYKHTDKREFLINLLARKNKYLTAKDVLENMKDDFPGISFDTIYR
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHH
NLSLFVELGIFEETDLSGERNFRLACTHEHHHHHFICMKCGKTKEIMMCPMDFLTEALPG
HHHHEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEEECCHHHHHHHCCC
YQIDGHKFEVYGECPECLQAS
CEECCCEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669