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The map label for this gene is murB

Identifier: 226224021

GI number: 226224021

Start: 1434394

End: 1435290

Strand: Reverse

Name: murB

Synonym: Lm4b_01429

Alternate gene names: 226224021

Gene position: 1435290-1434394 (Counterclockwise)

Preceding gene: 226224024

Following gene: 226224020

Centisome position: 49.28

GC content: 38.57

Gene sequence:

>897_bases
ATGAATAACTTACAAACACAGTTTCCGCATATAGCGATTAAATTAAATGAACCGTTGTCTAAGTATACCTATACAAAAAC
AGGCGGCGCGGCAGACGTATTCGTTATGCCAAAAACAATAGAAGAGACGCAAGAAGTGGTGGCCTACTGTCACCAAAATA
AAATCCCTCTTACTATTCTCGGAAATGGTTCCAATCTAATCATTAAAGACGGCGGAATTCGCGGCGTTATTTTACATCTT
GATTTACTACAAACCATTGAAAGAAACAATACCCAAATTATTGCCATGAGTGGTGCCAAACTCATTGATACAGCAAAATT
CGCTTTAGATGAAAGCTTAAGCGGACTTGAATTTGCTTGTGGTATTCCCGGATCTATTGGGGGAGCACTACATATGAATG
CAGGAGCATACGGAGGCGAAATTAGTGATGTTTTAGAAGCTGCAACCGTGCTGACACAAACAGGTGAATTAAAAAAACTA
AAACGTTCAGAACTAAAAGCAGCTTATCGCTTTAGTACTATTGCAGAAAAAAATTACATCGTATTAGATGCTACTTTTTC
TTTGGCCTTAGAAGAAAAAAACCTAATTCAAGCAAAAATGGATGAACTTACTGCAGCACGTGAAGCTAAACAACCATTAG
AGTATCCATCTTGTGGTAGTGTATTCAAACGTCCACCAGGTCACTTTGCGGGTAAATTAATTCAAGATAGTGGCTTGCAA
GGCCATATTATTGGCGGCGCGCAAGTTTCTTTAAAACATGCTGGATTTATCGTTAATATCGGTGGGGCAACTGCGACTGA
CTACATGAATTTAATTGCTTACGTCCAACAAACGGTTCGCGAGAAATTTGATGTAGAGTTAGAAACAGAAGTTAAAATCA
TAGGCGAAGATAAATAG

Upstream 100 bases:

>100_bases
TTAAGAAAAAAACTATGGAATTCTTTGTAAAAGAGAGGTTCCATGATAAAATAAAGGAAGTGATTTTTAAACTACAACCA
TGAAAGGTTTGAAATAAATA

Downstream 100 bases:

>100_bases
AGGAGGGCATCCATTTTTGAAAGAGCTTAGTTCATTTTTACAAAATCGTAGTGTGCGGCGAGTTGGCGTATTTATATTAA
TTGCCTTCGTTTTATACTTA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNNLQTQFPHIAIKLNEPLSKYTYTKTGGAADVFVMPKTIEETQEVVAYCHQNKIPLTILGNGSNLIIKDGGIRGVILHL
DLLQTIERNNTQIIAMSGAKLIDTAKFALDESLSGLEFACGIPGSIGGALHMNAGAYGGEISDVLEAATVLTQTGELKKL
KRSELKAAYRFSTIAEKNYIVLDATFSLALEEKNLIQAKMDELTAAREAKQPLEYPSCGSVFKRPPGHFAGKLIQDSGLQ
GHIIGGAQVSLKHAGFIVNIGGATATDYMNLIAYVQQTVREKFDVELETEVKIIGEDK

Sequences:

>Translated_298_residues
MNNLQTQFPHIAIKLNEPLSKYTYTKTGGAADVFVMPKTIEETQEVVAYCHQNKIPLTILGNGSNLIIKDGGIRGVILHL
DLLQTIERNNTQIIAMSGAKLIDTAKFALDESLSGLEFACGIPGSIGGALHMNAGAYGGEISDVLEAATVLTQTGELKKL
KRSELKAAYRFSTIAEKNYIVLDATFSLALEEKNLIQAKMDELTAAREAKQPLEYPSCGSVFKRPPGHFAGKLIQDSGLQ
GHIIGGAQVSLKHAGFIVNIGGATATDYMNLIAYVQQTVREKFDVELETEVKIIGEDK
>Mature_298_residues
MNNLQTQFPHIAIKLNEPLSKYTYTKTGGAADVFVMPKTIEETQEVVAYCHQNKIPLTILGNGSNLIIKDGGIRGVILHL
DLLQTIERNNTQIIAMSGAKLIDTAKFALDESLSGLEFACGIPGSIGGALHMNAGAYGGEISDVLEAATVLTQTGELKKL
KRSELKAAYRFSTIAEKNYIVLDATFSLALEEKNLIQAKMDELTAAREAKQPLEYPSCGSVFKRPPGHFAGKLIQDSGLQ
GHIIGGAQVSLKHAGFIVNIGGATATDYMNLIAYVQQTVREKFDVELETEVKIIGEDK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32252; Mature: 32252

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLQTQFPHIAIKLNEPLSKYTYTKTGGAADVFVMPKTIEETQEVVAYCHQNKIPLTIL
CCCCCCCCCEEEEEECCCHHHCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEE
GNGSNLIIKDGGIRGVILHLDLLQTIERNNTQIIAMSGAKLIDTAKFALDESLSGLEFAC
ECCCEEEEECCCCEEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEC
GIPGSIGGALHMNAGAYGGEISDVLEAATVLTQTGELKKLKRSELKAAYRFSTIAEKNYI
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VLDATFSLALEEKNLIQAKMDELTAAREAKQPLEYPSCGSVFKRPPGHFAGKLIQDSGLQ
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHCCCCE
GHIIGGAQVSLKHAGFIVNIGGATATDYMNLIAYVQQTVREKFDVELETEVKIIGEDK
EEEECCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC
>Mature Secondary Structure
MNNLQTQFPHIAIKLNEPLSKYTYTKTGGAADVFVMPKTIEETQEVVAYCHQNKIPLTIL
CCCCCCCCCEEEEEECCCHHHCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEE
GNGSNLIIKDGGIRGVILHLDLLQTIERNNTQIIAMSGAKLIDTAKFALDESLSGLEFAC
ECCCEEEEECCCCEEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEC
GIPGSIGGALHMNAGAYGGEISDVLEAATVLTQTGELKKLKRSELKAAYRFSTIAEKNYI
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VLDATFSLALEEKNLIQAKMDELTAAREAKQPLEYPSCGSVFKRPPGHFAGKLIQDSGLQ
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHCCCCE
GHIIGGAQVSLKHAGFIVNIGGATATDYMNLIAYVQQTVREKFDVELETEVKIIGEDK
EEEECCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]