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The map label for this gene is 226224019

Identifier: 226224019

GI number: 226224019

Start: 1432008

End: 1433276

Strand: Reverse

Name: 226224019

Synonym: Lm4b_01427

Alternate gene names: NA

Gene position: 1433276-1432008 (Counterclockwise)

Preceding gene: 226224020

Following gene: 226224018

Centisome position: 49.21

GC content: 37.83

Gene sequence:

>1269_bases
ATGGAAAAACATCTTTTTGTGATTTCATTAGACGCACTTGGAGCACTTGATTTAAAAGATACGACAGATTTGCCCGTTTT
ACGGGAATTAATTAAGACAGGAACTCACATCCAAGAAGTTGAAACCATTTATCCATCACTGACATATCCAGCGCACACAA
GTATTATCACGGGGCATTATCCCGCAACTCATGGGATTATTAATAACACAAAAGTTCAACCTGAAAAAGATTCTCCTGAT
TGGTATTGGTATAAAAAAGCCATTCAAGTACCAACACTTTATGATTTAGCCAAAGAGAAAGGGATGACGACCGCTGCTTT
TTTATGGCCGGTTGCAGCAAAAAGTGGAATTGATTATAATATTGCTGAAATTTTTCCAAATCGCTTTTGGTTAACGCAAA
TGATGGTGTCATTACATGCTAGCTCACCATTATTTTTAATAGATATGGACCGAAAATTTGGTCATCTGCGAAAGGGAATC
AACCAACCAGACTTAGATATATTTTTGACAGCTAGCGTAGTTGATACAATTAAAGCGAAAAGGCCAAGATTACTTTTAAC
ACATTTGGTTGATATGGATAGTATGCGACATGCGCACGGAGTAGATTCCCCTGAAGCAAAAGCGGCCTTAAAACGACACG
ATGAGCGGTTAGCTGCGATTATCCAAGCTACAAAAGAAGCTGGAATTTATGAAAATACTGTCTTTGCTTTTCTAGGTGAT
CATTATCAAATTAATGTAACACACGCCATACGCCTAAATGTCCTTTTTGCCGAACAGGGCTGGATGACCGTAGTGGACGA
TAAGATTACGGAATGGGATGTCTACGCTAAAAGTTGTGACGGTTCCAGTTATATTTACACAAAAAACAATCAACATAATC
AAGAAATCCAGCATTTACTTCAAAACATGGCTGAAATAGAAGAAATTTTGCCGAAAGAAGAAATAGCACTTCGTGGTGCT
GATCCTAATGCTACTTTTATGGTTGAAGGGAGGGCTGGTTTTTATTTTATGGATGATTTAGATGGACCGGTTTACGAAAA
AGTCACTGATGAAATGCTTGGAAAACCAGGTTACTATAAAGCAGTTCACGGTTATTCTCCTAAAAAGCCAGATTACAAAA
CCACGATTATTTTTAATGGACCTGGCATTAAAAAAGGAGACAAAATCAGCAATGCTCATTTAGTTGACGAAGCGCCTACA
TTTGCACACATTTTGGACTTACAATTTCCAAATACTGCTGGCTCTGTCATAGAAGCGATATTTGAATAG

Upstream 100 bases:

>100_bases
AATCGAACAGCCAAAGGACACAATCAGTCATACGTAATTCACACGGGGGTTCTTCCAGATTTTCTGGAAAATCCCTGTTT
TTTTGAAGGGGGAGAAAATA

Downstream 100 bases:

>100_bases
AAAAGGGGAGAAACACACTTGGCATATACAAAAGAGGAGAAAAGTTGGATTTTTCAAGATTGGGCGAATTCCGCCTACTC
AATCATGATAACAACTGCGA

Product: pyrophosphatase

Products: NA

Alternate protein names: Phosphodiesterase; Nucleotide Pyrophosphatase; Pyrophosphatase; Nucleotide Diphosphatase; Phosphoglyceromutase/Phosphopentomutase; Phosphodiesterase-Nucleotide Pyrophosphatase-Like Protein; AP Endonuclease; Phosphodiesterase/Nucleotide Pyrophosphatase Family Protein; Hydrolase; RB13-6 Antigen

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MEKHLFVISLDALGALDLKDTTDLPVLRELIKTGTHIQEVETIYPSLTYPAHTSIITGHYPATHGIINNTKVQPEKDSPD
WYWYKKAIQVPTLYDLAKEKGMTTAAFLWPVAAKSGIDYNIAEIFPNRFWLTQMMVSLHASSPLFLIDMDRKFGHLRKGI
NQPDLDIFLTASVVDTIKAKRPRLLLTHLVDMDSMRHAHGVDSPEAKAALKRHDERLAAIIQATKEAGIYENTVFAFLGD
HYQINVTHAIRLNVLFAEQGWMTVVDDKITEWDVYAKSCDGSSYIYTKNNQHNQEIQHLLQNMAEIEEILPKEEIALRGA
DPNATFMVEGRAGFYFMDDLDGPVYEKVTDEMLGKPGYYKAVHGYSPKKPDYKTTIIFNGPGIKKGDKISNAHLVDEAPT
FAHILDLQFPNTAGSVIEAIFE

Sequences:

>Translated_422_residues
MEKHLFVISLDALGALDLKDTTDLPVLRELIKTGTHIQEVETIYPSLTYPAHTSIITGHYPATHGIINNTKVQPEKDSPD
WYWYKKAIQVPTLYDLAKEKGMTTAAFLWPVAAKSGIDYNIAEIFPNRFWLTQMMVSLHASSPLFLIDMDRKFGHLRKGI
NQPDLDIFLTASVVDTIKAKRPRLLLTHLVDMDSMRHAHGVDSPEAKAALKRHDERLAAIIQATKEAGIYENTVFAFLGD
HYQINVTHAIRLNVLFAEQGWMTVVDDKITEWDVYAKSCDGSSYIYTKNNQHNQEIQHLLQNMAEIEEILPKEEIALRGA
DPNATFMVEGRAGFYFMDDLDGPVYEKVTDEMLGKPGYYKAVHGYSPKKPDYKTTIIFNGPGIKKGDKISNAHLVDEAPT
FAHILDLQFPNTAGSVIEAIFE
>Mature_422_residues
MEKHLFVISLDALGALDLKDTTDLPVLRELIKTGTHIQEVETIYPSLTYPAHTSIITGHYPATHGIINNTKVQPEKDSPD
WYWYKKAIQVPTLYDLAKEKGMTTAAFLWPVAAKSGIDYNIAEIFPNRFWLTQMMVSLHASSPLFLIDMDRKFGHLRKGI
NQPDLDIFLTASVVDTIKAKRPRLLLTHLVDMDSMRHAHGVDSPEAKAALKRHDERLAAIIQATKEAGIYENTVFAFLGD
HYQINVTHAIRLNVLFAEQGWMTVVDDKITEWDVYAKSCDGSSYIYTKNNQHNQEIQHLLQNMAEIEEILPKEEIALRGA
DPNATFMVEGRAGFYFMDDLDGPVYEKVTDEMLGKPGYYKAVHGYSPKKPDYKTTIIFNGPGIKKGDKISNAHLVDEAPT
FAHILDLQFPNTAGSVIEAIFE

Specific function: Unknown

COG id: COG1524

COG function: function code R; Uncharacterized proteins of the AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI170650661, Length=229, Percent_Identity=26.6375545851528, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI111160296, Length=231, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47590; Mature: 47590

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHLFVISLDALGALDLKDTTDLPVLRELIKTGTHIQEVETIYPSLTYPAHTSIITGHY
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCC
PATHGIINNTKVQPEKDSPDWYWYKKAIQVPTLYDLAKEKGMTTAAFLWPVAAKSGIDYN
CCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHCCCEEHHHHHHHHHCCCCCEE
IAEIFPNRFWLTQMMVSLHASSPLFLIDMDRKFGHLRKGINQPDLDIFLTASVVDTIKAK
HHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEHHHHHHHHCC
RPRLLLTHLVDMDSMRHAHGVDSPEAKAALKRHDERLAAIIQATKEAGIYENTVFAFLGD
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
HYQINVTHAIRLNVLFAEQGWMTVVDDKITEWDVYAKSCDGSSYIYTKNNQHNQEIQHLL
CEEEEEEEEEEEEEEEECCCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHH
QNMAEIEEILPKEEIALRGADPNATFMVEGRAGFYFMDDLDGPVYEKVTDEMLGKPGYYK
HHHHHHHHHCCHHHEEEECCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEE
AVHGYSPKKPDYKTTIIFNGPGIKKGDKISNAHLVDEAPTFAHILDLQFPNTAGSVIEAI
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHHHHHHH
FE
CC
>Mature Secondary Structure
MEKHLFVISLDALGALDLKDTTDLPVLRELIKTGTHIQEVETIYPSLTYPAHTSIITGHY
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCC
PATHGIINNTKVQPEKDSPDWYWYKKAIQVPTLYDLAKEKGMTTAAFLWPVAAKSGIDYN
CCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHCCCEEHHHHHHHHHCCCCCEE
IAEIFPNRFWLTQMMVSLHASSPLFLIDMDRKFGHLRKGINQPDLDIFLTASVVDTIKAK
HHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEHHHHHHHHCC
RPRLLLTHLVDMDSMRHAHGVDSPEAKAALKRHDERLAAIIQATKEAGIYENTVFAFLGD
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
HYQINVTHAIRLNVLFAEQGWMTVVDDKITEWDVYAKSCDGSSYIYTKNNQHNQEIQHLL
CEEEEEEEEEEEEEEEECCCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHH
QNMAEIEEILPKEEIALRGADPNATFMVEGRAGFYFMDDLDGPVYEKVTDEMLGKPGYYK
HHHHHHHHHCCHHHEEEECCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEE
AVHGYSPKKPDYKTTIIFNGPGIKKGDKISNAHLVDEAPTFAHILDLQFPNTAGSVIEAI
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHHHHHHH
FE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA