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The map label for this gene is pgsA [H]

Identifier: 226223997

GI number: 226223997

Start: 1406959

End: 1407537

Strand: Direct

Name: pgsA [H]

Synonym: Lm4b_01405

Alternate gene names: 226223997

Gene position: 1406959-1407537 (Clockwise)

Preceding gene: 226223996

Following gene: 226223998

Centisome position: 48.3

GC content: 35.92

Gene sequence:

>579_bases
ATGAATTTACCTAATAAATTGACGGTTATCCGAATTTTTATGATACCAATTTTTGTCATTCTTTGTGTAGTGCCATTCGA
CTGGGGAAGCGTTACTTGGCTTGATTCCACTATTCCGGTAACTAGTTTAGTAGCAACTATTATTTTCATTGTAGCGGCTC
TTACAGACTGGTTTGATGGACATTTAGCTCGCAAGTATAATTTGATTACTAACTTCGGTAAATTTGCTGATCCGATGGCT
GATAAACTACTTGTAGCAGCTGCATTTATTATTCTTGTAGAAATGCATATCGCTCCATCTTGGGTAGTTATTCTTATTAT
TAGTCGTGAACTAGCTGTTACTGGTCTTCGCTTACTTTTAGTTGAAGGCGGAGAAGTACTTGCAGCTGGTCAACTTGGTA
AAATTAAAACATTCACACAAATGATTGCTATTCCGCTTATGTTATTAAATAATTTTCCATTTGCTTGGACAGGTATTCGT
GTGGATTTAGTGTTCTTGTATGTATGTGCATTCTTTGCAGTATGGTCAGGTATCGATTATTTCTACAAAAATCGTGGTGT
TTTCAAAGGGTCTATGTAA

Upstream 100 bases:

>100_bases
TGCTGAATAATTTGTTTTATATGGCGAAATCTACTCATTAGATTTCGCCAACATTTTTTATAATTACATACTTTTCAAAT
GTAAAAAAGGAGAGAAAAAG

Downstream 100 bases:

>100_bases
TAAATGAAAAAAGCATACCATTGTGTGCTTTTTTCTATACAAAAAATCGAATTGGAGATGGGGCAAGATGGCAAGTGCAG
AAATCATTGCAGTAGGAACA

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNLPNKLTVIRIFMIPIFVILCVVPFDWGSVTWLDSTIPVTSLVATIIFIVAALTDWFDGHLARKYNLITNFGKFADPMA
DKLLVAAAFIILVEMHIAPSWVVILIISRELAVTGLRLLLVEGGEVLAAGQLGKIKTFTQMIAIPLMLLNNFPFAWTGIR
VDLVFLYVCAFFAVWSGIDYFYKNRGVFKGSM

Sequences:

>Translated_192_residues
MNLPNKLTVIRIFMIPIFVILCVVPFDWGSVTWLDSTIPVTSLVATIIFIVAALTDWFDGHLARKYNLITNFGKFADPMA
DKLLVAAAFIILVEMHIAPSWVVILIISRELAVTGLRLLLVEGGEVLAAGQLGKIKTFTQMIAIPLMLLNNFPFAWTGIR
VDLVFLYVCAFFAVWSGIDYFYKNRGVFKGSM
>Mature_192_residues
MNLPNKLTVIRIFMIPIFVILCVVPFDWGSVTWLDSTIPVTSLVATIIFIVAALTDWFDGHLARKYNLITNFGKFADPMA
DKLLVAAAFIILVEMHIAPSWVVILIISRELAVTGLRLLLVEGGEVLAAGQLGKIKTFTQMIAIPLMLLNNFPFAWTGIR
VDLVFLYVCAFFAVWSGIDYFYKNRGVFKGSM

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=191, Percent_Identity=36.1256544502618, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21463; Mature: 21463

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTVIRIFMIPIFVILCVVPFDWGSVTWLDSTIPVTSLVATIIFIVAALTDWFDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
HLARKYNLITNFGKFADPMADKLLVAAAFIILVEMHIAPSWVVILIISRELAVTGLRLLL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHEE
VEGGEVLAAGQLGKIKTFTQMIAIPLMLLNNFPFAWTGIRVDLVFLYVCAFFAVWSGIDY
EECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHH
FYKNRGVFKGSM
HHHCCCCCCCCC
>Mature Secondary Structure
MNLPNKLTVIRIFMIPIFVILCVVPFDWGSVTWLDSTIPVTSLVATIIFIVAALTDWFDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
HLARKYNLITNFGKFADPMADKLLVAAAFIILVEMHIAPSWVVILIISRELAVTGLRLLL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHEE
VEGGEVLAAGQLGKIKTFTQMIAIPLMLLNNFPFAWTGIRVDLVFLYVCAFFAVWSGIDY
EECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHH
FYKNRGVFKGSM
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]