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The map label for this gene is yqgN [H]

Identifier: 226223937

GI number: 226223937

Start: 1347719

End: 1348258

Strand: Direct

Name: yqgN [H]

Synonym: Lm4b_01344

Alternate gene names: 226223937

Gene position: 1347719-1348258 (Clockwise)

Preceding gene: 226223936

Following gene: 226223938

Centisome position: 46.27

GC content: 32.96

Gene sequence:

>540_bases
ATGGAAGACAAACGACTGATACGCGAGAAAATCTTACGGAATTTGAATAGCCTTGATAGAGTAGAACATCGCGAACGTTC
TATTAGATTAGCGGAAAAACTATTTTTATTACCAGAATGGGAAAATGCAAAGGTTGTTGGTATCACATTAGCAAGACACC
CTGAAATCGAAACAGAAGCAATCATCCTACAAGCAAAAAAAGAAGGGAAAACCATTTTAATTCCAAAAACATATTATCCT
AGCAAAAAAATGGAGTTTAAAAAGATGGATTCGATACATCCTTTAATAAAATCTAAGTTTGGTATTTTAGAACCAAATGA
ATTAGCAGAAACAGTTGATAAAAAAGTAATTGACTTACTAATTGTTCCTGGAGTTGCCTTTAATAAAGATCATTATAGAA
TCGGTTTTGGCGGAGGATTTTACGATAGATTTTTAACGGATTTTCAAGGACATACAGTGTCCTTGTACCTTTATGAACAA
CAAATAGAGTTTACACCTGAAAAGCATGACGAACCAGTTTCTATTTTAATTGGAGGATAA

Upstream 100 bases:

>100_bases
TGTCCAAGATTACGCCGTGTAACTTTACACCGCGAAACTAAGTAAGCAGCAGGATCTCCATTCTGTTGCTTTTTTTATTA
ACAAAAAGGGGGAAGCCAAA

Downstream 100 bases:

>100_bases
GGAAAAATAATTCTATAGAAAATAGGGTGGATTGTTTACAACACCCTTTTTTTTGCGTATAGTAGTAAATATAATTTGTA
ATGAAAGCAGGGAATTTTTT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MEDKRLIREKILRNLNSLDRVEHRERSIRLAEKLFLLPEWENAKVVGITLARHPEIETEAIILQAKKEGKTILIPKTYYP
SKKMEFKKMDSIHPLIKSKFGILEPNELAETVDKKVIDLLIVPGVAFNKDHYRIGFGGGFYDRFLTDFQGHTVSLYLYEQ
QIEFTPEKHDEPVSILIGG

Sequences:

>Translated_179_residues
MEDKRLIREKILRNLNSLDRVEHRERSIRLAEKLFLLPEWENAKVVGITLARHPEIETEAIILQAKKEGKTILIPKTYYP
SKKMEFKKMDSIHPLIKSKFGILEPNELAETVDKKVIDLLIVPGVAFNKDHYRIGFGGGFYDRFLTDFQGHTVSLYLYEQ
QIEFTPEKHDEPVSILIGG
>Mature_179_residues
MEDKRLIREKILRNLNSLDRVEHRERSIRLAEKLFLLPEWENAKVVGITLARHPEIETEAIILQAKKEGKTILIPKTYYP
SKKMEFKKMDSIHPLIKSKFGILEPNELAETVDKKVIDLLIVPGVAFNKDHYRIGFGGGFYDRFLTDFQGHTVSLYLYEQ
QIEFTPEKHDEPVSILIGG

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=169, Percent_Identity=30.1775147928994, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 20775; Mature: 20775

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKRLIREKILRNLNSLDRVEHRERSIRLAEKLFLLPEWENAKVVGITLARHPEIETEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCEE
IILQAKKEGKTILIPKTYYPSKKMEFKKMDSIHPLIKSKFGILEPNELAETVDKKVIDLL
EEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
IVPGVAFNKDHYRIGFGGGFYDRFLTDFQGHTVSLYLYEQQIEFTPEKHDEPVSILIGG
EECCEEECCCCEEEEECCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEEEECC
>Mature Secondary Structure
MEDKRLIREKILRNLNSLDRVEHRERSIRLAEKLFLLPEWENAKVVGITLARHPEIETEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCEE
IILQAKKEGKTILIPKTYYPSKKMEFKKMDSIHPLIKSKFGILEPNELAETVDKKVIDLL
EEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
IVPGVAFNKDHYRIGFGGGFYDRFLTDFQGHTVSLYLYEQQIEFTPEKHDEPVSILIGG
EECCEEECCCCEEEEECCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]