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The map label for this gene is rbgA

Identifier: 226223875

GI number: 226223875

Start: 1281232

End: 1282095

Strand: Direct

Name: rbgA

Synonym: Lm4b_01282

Alternate gene names: 226223875

Gene position: 1281232-1282095 (Clockwise)

Preceding gene: 226223874

Following gene: 226223876

Centisome position: 43.99

GC content: 38.54

Gene sequence:

>864_bases
ATGACAATTCAGTGGTTTCCAGGTCATATGGCCAAAGCTCGCCGTGAGGTAACAGAAAAATTAAAACTAGTAGATGTGAT
TTTTGAATTGGTAGATGCGCGTATCCCGCTCTCTTCCTCTAATCCCATGCTAGAAGAAATTATCCACCAAAAAAGACGAG
TGATTATTTTAAATAAAGCAGATACTGCCGATGAAAAAACAACAAAAGAATGGATTGACTACTTTGCTGAGAAAGGCTTG
CCAGCAGTTGCTGTGAATGCTCAAGAAGGTAAAGGACTATTCAAAATAGAACAAGCCGCCGAAAAATTAATGGCTGAAAA
ATTCGACCGTTTAAGAAGTAAAGGTATGAAGCCAAGAGCAATTCGTGCGATGATTTTAGGTATTCCGAATGTTGGTAAAT
CAACATTAATCAATCGACTAGCGAAAAAAAATATTGCACGGACAGGTAATAAACCTGGTGTAACTAAAGCACAGCAATGG
ATTAAAGTGGGAAAAACATTAGAACTTCTGGATACACCAGGGATTCTTTGGCCTAAATTTGAAGATCAAGAAATTGGCTA
CAAATTAGCTCTTACTGGTGCAATTAAAGATGATTTACTACAAATGGAAGAGATCGCTGGTTACGGTTTGCGCTTTTTAG
AAAAACATTATCCCGACAGACTTCAAAACTGGCTGAAAGTAGAGACAGTCTCTGAAGATCCTATCGAAACACTTGCTTTT
ATTGCTGAAAAAAGAGGGCTTCTAGATCGATACAATGATCCAGATTATTCTCGCGCAGCCGAAACGGTAGTTCGAGAAAT
TCGTCAGCAAAAGTTAGGGAGAATGTCGTTTGATTTCCCAAATTGGGAAGATGAAGTCGAATGA

Upstream 100 bases:

>100_bases
TCGGATAATTGGGCCAATTCCATTTAGCAAGGTGTTAGGAACAACACCGATTTGTTACTGGCCGATTGAAGATGCCAAAC
TTATAGATTAGGAGTATATA

Downstream 100 bases:

>100_bases
GCGATTCCATATCCGTTATCCGAGAAAAACTAAACCAAGTCACATCAGAACATGATCCCTTTTTTCGGAAATGCATGCAA
GATGAGCGTAAAGGTGTAGA

Product: ribosomal biogenesis GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFAEKGL
PAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQW
IKVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEEIAGYGLRFLEKHYPDRLQNWLKVETVSEDPIETLAF
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDEVE

Sequences:

>Translated_287_residues
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFAEKGL
PAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQW
IKVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEEIAGYGLRFLEKHYPDRLQNWLKVETVSEDPIETLAF
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDEVE
>Mature_286_residues
TIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFAEKGLP
AVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWI
KVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEEIAGYGLRFLEKHYPDRLQNWLKVETVSEDPIETLAFI
AEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDEVE

Specific function: Binds GTP and GDP [H]

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI93277113, Length=296, Percent_Identity=32.4324324324324, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI296317324, Length=184, Percent_Identity=33.695652173913, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI9506611, Length=184, Percent_Identity=33.695652173913, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7019419, Length=263, Percent_Identity=27.3764258555133, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI45643129, Length=186, Percent_Identity=30.1075268817204, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45643127, Length=186, Percent_Identity=30.1075268817204, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45593130, Length=271, Percent_Identity=26.9372693726937, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193211047, Length=227, Percent_Identity=30.3964757709251, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17534827, Length=274, Percent_Identity=30.6569343065693, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32563985, Length=244, Percent_Identity=27.0491803278689, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990926, Length=244, Percent_Identity=27.0491803278689, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143545, Length=285, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32563983, Length=244, Percent_Identity=27.0491803278689, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115535155, Length=286, Percent_Identity=26.5734265734266, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71982363, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323744, Length=229, Percent_Identity=30.1310043668122, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324381, Length=263, Percent_Identity=26.2357414448669, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320842, Length=170, Percent_Identity=31.1764705882353, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI85815858, Length=306, Percent_Identity=32.0261437908497, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28572990, Length=174, Percent_Identity=35.0574712643678, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922460, Length=256, Percent_Identity=26.5625, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR019991
- InterPro:   IPR016478
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32906; Mature: 32774

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKA
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
DTADEKTTKEWIDYFAEKGLPAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWIKVGKTLELLDTPGILWPKF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCC
EDQEIGYKLALTGAIKDDLLQMEEIAGYGLRFLEKHYPDRLQNWLKVETVSEDPIETLAF
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEECCCCCHHHHHHH
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDEVE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
DTADEKTTKEWIDYFAEKGLPAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWIKVGKTLELLDTPGILWPKF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCC
EDQEIGYKLALTGAIKDDLLQMEEIAGYGLRFLEKHYPDRLQNWLKVETVSEDPIETLAF
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEECCCCCHHHHHHH
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDEVE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]