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The map label for this gene is pbpX [H]

Identifier: 226223169

GI number: 226223169

Start: 582520

End: 583713

Strand: Direct

Name: pbpX [H]

Synonym: Lm4b_00566

Alternate gene names: 226223169

Gene position: 582520-583713 (Clockwise)

Preceding gene: 226223167

Following gene: 226223177

Centisome position: 20.0

GC content: 34.67

Gene sequence:

>1194_bases
ATGAATCGACGCGAAAGACGTAAACACAAAAGACGCAAGAACATGATTATCGTGTTGAGTACTGTATTTCTACTGTTTAT
TGCCACAAGTTGGATGATATACGAATTCAAAAGTAAACAAGAGCAAACAGTATCCGCACCTACTAAGAAGAAAGCAGCAA
CCGCAACAAACCCACCGGAAAATGCAGCAACTAATGAGCCTGAAGAAACGAAAGAGCCTGAACCAGTAGAAGAAAAGCCA
AAGGAAACAATTGTAAAAAATCAAGAAATTGATAACTATTTACAAAAAATTGGTTTTAGTGGTTCGGCACTGGTTGTTCG
CGATGGAAAAACTATCATACAAAAAGGGTATATGTATGCAAATCGTGATGAAAAAGTATTGAATACACCAGATACTTTGT
TTTATATTGGCTCTTCTCAAAAAGCAATCATAGCAACGGCACTTTTACAATTAGAAGAAAAAGGTAAAATAAATACGAAT
GATCCAATTTCGAAGTATATACCTGACTTTCCTAATGGTAATAAGATTTTAGTGAAGAACTTTATGAATCATACATCTGG
TATAGTTGGACGACCAAAATTAACGAGTAATATGACACCGGATCAAATTATTAAAGCTATTGAAAAGCGAGGAATTAAAT
CACAACCTGGGAAATGGGATTATTTGGATGCTAATTATGCTGTAGTAGGTTATCTTGTAGAAAAAGTTAGTGGGCAACCT
TTAGCTACCTATCTTCAAGAAAATATATTTACCCCTGCAGGAATGAAGCATACAGGATACTATCAAAAAGATGTTGATGG
GGGAAAAAACGTATCAACAGGCTATAAAATTGATGAAAATGGAGTCTTTCAAAGTCCAAAGCTTGCAGACTTAACGAAAT
TATATGGTGCAGGGGACATTAGTATGTCTACAACGGATATGTATTTGTTTGACAAAGCATTGATGGATAAAAAATTGATT
TCTGAAGCAAGTTTGAAAAAAATGTTCACATCAGGAAGCAAATCAACTTATGGAATGGGATTCTATGTGGATCCAGGTAG
TTATAATAGTCACGGAGTTGTGACCGGTTGGGACGTATCTAATAGTGTCAGTCATACAGGAAGAACTTATGTTATATTAT
TCTCCAACGTCCAAAACCACATTGCTTCATTCGGAAAAGTGAATAATGATATTTATGGTTTCTTAAATAAATAA

Upstream 100 bases:

>100_bases
GTGGAGTGTTAGGTATTGATAGAAATTTGGGATATTTTCTATTAATACATTCTCTTTTGGGAAAGTCATTTAACGATTAG
ACTAGACCAGGAGTGATGAA

Downstream 100 bases:

>100_bases
TAAAAAAAACCGATTCTATTTGTAGAATCGGGTTTTTTTATTATTTACCAGTAATTTGTTTTACAGCATCTTCCATTTGA
TAAAGTTGAGCAGAGGCACT

Product: penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNRRERRKHKRRKNMIIVLSTVFLLFIATSWMIYEFKSKQEQTVSAPTKKKAATATNPPENAATNEPEETKEPEPVEEKP
KETIVKNQEIDNYLQKIGFSGSALVVRDGKTIIQKGYMYANRDEKVLNTPDTLFYIGSSQKAIIATALLQLEEKGKINTN
DPISKYIPDFPNGNKILVKNFMNHTSGIVGRPKLTSNMTPDQIIKAIEKRGIKSQPGKWDYLDANYAVVGYLVEKVSGQP
LATYLQENIFTPAGMKHTGYYQKDVDGGKNVSTGYKIDENGVFQSPKLADLTKLYGAGDISMSTTDMYLFDKALMDKKLI
SEASLKKMFTSGSKSTYGMGFYVDPGSYNSHGVVTGWDVSNSVSHTGRTYVILFSNVQNHIASFGKVNNDIYGFLNK

Sequences:

>Translated_397_residues
MNRRERRKHKRRKNMIIVLSTVFLLFIATSWMIYEFKSKQEQTVSAPTKKKAATATNPPENAATNEPEETKEPEPVEEKP
KETIVKNQEIDNYLQKIGFSGSALVVRDGKTIIQKGYMYANRDEKVLNTPDTLFYIGSSQKAIIATALLQLEEKGKINTN
DPISKYIPDFPNGNKILVKNFMNHTSGIVGRPKLTSNMTPDQIIKAIEKRGIKSQPGKWDYLDANYAVVGYLVEKVSGQP
LATYLQENIFTPAGMKHTGYYQKDVDGGKNVSTGYKIDENGVFQSPKLADLTKLYGAGDISMSTTDMYLFDKALMDKKLI
SEASLKKMFTSGSKSTYGMGFYVDPGSYNSHGVVTGWDVSNSVSHTGRTYVILFSNVQNHIASFGKVNNDIYGFLNK
>Mature_397_residues
MNRRERRKHKRRKNMIIVLSTVFLLFIATSWMIYEFKSKQEQTVSAPTKKKAATATNPPENAATNEPEETKEPEPVEEKP
KETIVKNQEIDNYLQKIGFSGSALVVRDGKTIIQKGYMYANRDEKVLNTPDTLFYIGSSQKAIIATALLQLEEKGKINTN
DPISKYIPDFPNGNKILVKNFMNHTSGIVGRPKLTSNMTPDQIIKAIEKRGIKSQPGKWDYLDANYAVVGYLVEKVSGQP
LATYLQENIFTPAGMKHTGYYQKDVDGGKNVSTGYKIDENGVFQSPKLADLTKLYGAGDISMSTTDMYLFDKALMDKKLI
SEASLKKMFTSGSKSTYGMGFYVDPGSYNSHGVVTGWDVSNSVSHTGRTYVILFSNVQNHIASFGKVNNDIYGFLNK

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=369, Percent_Identity=24.6612466124661, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786574, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533026, Length=348, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 44391; Mature: 44391

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRERRKHKRRKNMIIVLSTVFLLFIATSWMIYEFKSKQEQTVSAPTKKKAATATNPPE
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHEEEHHCCCHHHHCCCCHHCCCCCCCCCC
NAATNEPEETKEPEPVEEKPKETIVKNQEIDNYLQKIGFSGSALVVRDGKTIIQKGYMYA
CCCCCCCHHCCCCCCHHHCCHHHHHCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCEEE
NRDEKVLNTPDTLFYIGSSQKAIIATALLQLEEKGKINTNDPISKYIPDFPNGNKILVKN
CCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEHHHH
FMNHTSGIVGRPKLTSNMTPDQIIKAIEKRGIKSQPGKWDYLDANYAVVGYLVEKVSGQP
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCCCH
LATYLQENIFTPAGMKHTGYYQKDVDGGKNVSTGYKIDENGVFQSPKLADLTKLYGAGDI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCC
SMSTTDMYLFDKALMDKKLISEASLKKMFTSGSKSTYGMGFYVDPGSYNSHGVVTGWDVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEECCCC
NSVSHTGRTYVILFSNVQNHIASFGKVNNDIYGFLNK
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MNRRERRKHKRRKNMIIVLSTVFLLFIATSWMIYEFKSKQEQTVSAPTKKKAATATNPPE
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHEEEHHCCCHHHHCCCCHHCCCCCCCCCC
NAATNEPEETKEPEPVEEKPKETIVKNQEIDNYLQKIGFSGSALVVRDGKTIIQKGYMYA
CCCCCCCHHCCCCCCHHHCCHHHHHCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCEEE
NRDEKVLNTPDTLFYIGSSQKAIIATALLQLEEKGKINTNDPISKYIPDFPNGNKILVKN
CCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEHHHH
FMNHTSGIVGRPKLTSNMTPDQIIKAIEKRGIKSQPGKWDYLDANYAVVGYLVEKVSGQP
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCCCH
LATYLQENIFTPAGMKHTGYYQKDVDGGKNVSTGYKIDENGVFQSPKLADLTKLYGAGDI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCC
SMSTTDMYLFDKALMDKKLISEASLKKMFTSGSKSTYGMGFYVDPGSYNSHGVVTGWDVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEECCCC
NSVSHTGRTYVILFSNVQNHIASFGKVNNDIYGFLNK
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]