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The map label for this gene is hexR [C]

Identifier: 226223152

GI number: 226223152

Start: 562309

End: 563061

Strand: Direct

Name: hexR [C]

Synonym: Lm4b_00549

Alternate gene names: 226223152

Gene position: 562309-563061 (Clockwise)

Preceding gene: 226223148

Following gene: 226223153

Centisome position: 19.31

GC content: 38.65

Gene sequence:

>753_bases
ATGCTTTTTTTGGATAAAAATTTGGAATTAAATGATACGGAATTAGATATTTATAATTATATTGTGGCGAATTTAGATAA
AGTTGTTTATATGCGGATTCGCGATTTGGCGACGGAAGCGCATGTGAGTACGACGACAATTCTACGTTTTTGCCGAAAAT
TTGGTTGTAATGGTTTTTCGGAGTTTCGGGTGAAATTACAGCTTTATTTGGAAGAGCAGAAGTTGGCGCAAATCGATATG
GCGGATGAAACGACTTATATTGATTTTCTGAAACGGACGGCGCAACCTGAGTTTAAAGCGCAAATTCAAAACGCGGTCGA
GATTCTTCGTGATCGCGAACTGGTTTTATTTGCTGGGGTGGGTTCATCGGGTGTAATTGCTGAATATGGCGCGATTTATT
TTTCGTCATTATTTACGCTGGCGCTACATATTGAAGATCCGCTTAACCACCCGTTTTACCATTTATCGAGCAAATTATCC
GATAAAATCTGTATGATTGCGATTTCGGTGGAAGGGGAAAATGAAGACATCATTCGCTACATTCACCAACTGAAAGCGCA
AAATTGTAAAGTAATTTCGATTACGAATAGCGCGAAATCAACAATTGCAAGGCTATCTGACGCGAACATCGCTTATTATA
TTAATAAGGAAATGTACCAGGAAGCGAATATCACGTCCCAACTACCGGCGCTATATACAATTGAAAATATTGCCCGGGAA
ATAAGAACGCAAATTGATAAAGAGAAAATGTAA

Upstream 100 bases:

>100_bases
GTATTTGACGAGGTTTAGGTAAGGATTTTCTAAGTAGGAACTTGTCACATTTGAGTAACGAGGTGTTACATGGTAAAATA
AAGCGAAAAGAGGTGCGAAA

Downstream 100 bases:

>100_bases
AAAGCTACGTTTTGCTTGGATTTCCGAGCAAAACTTTTTTTGTAACAAAATTGTCACTTACGAAGAATTTTTTAATTTGC
TACGATAGTTCTTTGGAGGT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDM
ADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLS
DKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIARE
IRTQIDKEKM

Sequences:

>Translated_250_residues
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDM
ADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLS
DKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIARE
IRTQIDKEKM
>Mature_250_residues
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDM
ADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLS
DKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIARE
IRTQIDKEKM

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28731; Mature: 28731

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFS
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EFRVKLQLYLEEQKLAQIDMADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGV
HHEEEEEEEECHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEC
GSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLSDKICMIAISVEGENEDIIRY
CCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHH
IHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIARE
HHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEEECHHHHHHCCCHHHCCHHHHHHHHHHH
IRTQIDKEKM
HHHHHHHCCC
>Mature Secondary Structure
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFS
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EFRVKLQLYLEEQKLAQIDMADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGV
HHEEEEEEEECHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEC
GSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLSDKICMIAISVEGENEDIIRY
CCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHH
IHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIARE
HHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEEECHHHHHHCCCHHHCCHHHHHHHHHHH
IRTQIDKEKM
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]