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The map label for this gene is rpe [H]

Identifier: 226223130

GI number: 226223130

Start: 536645

End: 537295

Strand: Direct

Name: rpe [H]

Synonym: Lm4b_00527

Alternate gene names: 226223130

Gene position: 536645-537295 (Clockwise)

Preceding gene: 226223129

Following gene: 226223131

Centisome position: 18.42

GC content: 38.56

Gene sequence:

>651_bases
GTGGCAAAAATAGTTCCGTCTGTTTTTGGAGCAGACATCGGCAGAATTAATGAACAGTTAGAGGTTCTAGAGAAAAATGG
CATTGATTTATTACATGTGGATATGATGGATGGCTCGTTCGTCCCGAACATTGCTTTTGGTCCAGATCAAATCAAAATGA
TGAAAAAAGGCACGAAGCTTCAATTTGATGTTCATATGATGGTGTATGAACCAGACCGTTATATTCCAAGATTAGTGGAA
GCAGGCGCACATATGATTACAGTCCACCAAGAAGCAACAACTCATTTGCATCGTACAATTCAACTAATTAAAAGTTACGG
AGTTCGCGCGGGAGTGGTATTAAATCCTGGTACACCACCAAGCACTTTGGAATACGTGTTAGATGATATTGACTGTATTT
TGCTTATGACTGTAAATCCAGGCTTAGGTGGTCAAAAATTCTTCCAATCAAGTTTAGAAAAAATCAGAAAAACCAAAGCA
TATATTGGAAATCGTCCTATTCAAATTGAAGTAGATGGCGGAGTAAATGCTGAACTCGCGAAAGAATGCACACTTGCAGG
CGCGGATTTAATCGTTGTAGGATCTTACTTATTTGAAGGAGATATCGAAGCGAATTTGGAGAAGTTATCGAAAGGAGTTT
TAACAGAATGA

Upstream 100 bases:

>100_bases
GAATCAACTAAATTACTCCATTTTAGTCAACAAAAATTAAAACTAAGTGACAAAGAAAAGTTACAAAAAATTATAGAAAT
TCAATCTTGAGGTGATAATA

Downstream 100 bases:

>100_bases
AAGCTTTAAAATTATATGGAAAAAGAGATTTGCGTTATGAAGAAGCGGATATGCCAACAATCGAACAGCCAGATGATGTG
ATTTTGAAAGTGAAAACGGT

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MAKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVE
AGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKA
YIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE

Sequences:

>Translated_216_residues
MAKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVE
AGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKA
YIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE
>Mature_215_residues
AKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEA
GAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAY
IGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=217, Percent_Identity=35.4838709677419, Blast_Score=141, Evalue=4e-34,
Organism=Homo sapiens, GI219879828, Length=217, Percent_Identity=33.1797235023041, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI24307923, Length=171, Percent_Identity=30.9941520467836, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1789788, Length=199, Percent_Identity=44.7236180904523, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=36.734693877551, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790754, Length=206, Percent_Identity=31.0679611650485, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17552948, Length=200, Percent_Identity=36.5, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322341, Length=208, Percent_Identity=34.1346153846154, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24586301, Length=195, Percent_Identity=37.4358974358974, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23751; Mature: 23620

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKL
CCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCEE
QFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPP
EEEEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
STLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELA
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
KECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE
HHHHHCCCCEEEEEHHHCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKL
CCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCEE
QFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPP
EEEEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCH
STLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELA
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
KECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE
HHHHHCCCCEEEEEHHHCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]