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The map label for this gene is aroD

Identifier: 226223117

GI number: 226223117

Start: 525212

End: 525970

Strand: Direct

Name: aroD

Synonym: Lm4b_00514

Alternate gene names: 226223117

Gene position: 525212-525970 (Clockwise)

Preceding gene: 226223116

Following gene: 226223120

Centisome position: 18.03

GC content: 41.24

Gene sequence:

>759_bases
ATGAATAAAGTAGTCGTAAAGAATGTTACGTTTGGTGAAGGTGCGCCAAAAATTTGTGTACCAATGGTCGGTAAAACGGT
TGCTGCGCTTAAAGAAGAAGCAGAAATGTTACAAACAATTGATTTGGACGTTGTCGAATGGCGCGTTGACTTTTTTGAAG
ACGTCAAAGATTTAGCTAAAGTGGAAGCTGCGCTAGATGAAATTCGCACAATTTTACCAGAAACACCGATTTTATTCACT
TTCCGCAGTGCAAAAGAGGGCGGCGAGTTAGCTGTCAGTGACGAATTTTATTTTGAATTAAATGAAACTCTAGCTGGAAC
GGGAAAAATTGATTTAGTAGATGTGGAACTTTTCAATGAAGAAGCGGACGTTTTACGCTTAATTGAAACAGCTCACAAGA
ACAATGTAAAAGTAGTGATGTCGAACCATGATTTTGATAAAACACCTGCGAAGGAAGAAATCGTTTCTCGTTTAACTCGC
ATGGAAGCACTTGGCGCGGACCTTCCGAAAATCGCCGTCATGCCAAAATCTGCTGGAGACGTACTAACTTTACTAGATGC
AACGAATACTGTATCTGAAAAAGCTAATCAACCAATCATTACGATGTCGATGGCGGGCACTGGTGTCATCAGTCGTCTTG
CTGGCGAAGTTTTTGGCTCCGCAATGACATTTGGCGCTGCGAAAAAAGCATCGGCTCCTGGGCAAATTGATGTTAATGAG
TTACGCCATGTCCTTGATTTACTGCACAAACAATTTTAA

Upstream 100 bases:

>100_bases
TGCCAGTGGATTACATTAAAGAAATCCTATTTTAAAAACTTGCAAAAGAACAAGGTTATCGCTAATCTTAAGACATAATA
TCGAATGAGGAGAATTATAC

Downstream 100 bases:

>100_bases
TAAATACTAAAAAAGTAGCAAGTTTCTTTGATGAAAAGAAACTTGCTACTTTTTTTATCTAGAATGAATTATTTTGTTAA
TAGACTACTTTTTATAAACG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEAALDEIRTILPETPILFT
FRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTR
MEALGADLPKIAVMPKSAGDVLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNE
LRHVLDLLHKQF

Sequences:

>Translated_252_residues
MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEAALDEIRTILPETPILFT
FRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTR
MEALGADLPKIAVMPKSAGDVLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNE
LRHVLDLLHKQF
>Mature_252_residues
MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEAALDEIRTILPETPILFT
FRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTR
MEALGADLPKIAVMPKSAGDVLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNE
LRHVLDLLHKQF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=251, Percent_Identity=55.7768924302789, Blast_Score=283, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 27504; Mature: 27504

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAK
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VEAALDEIRTILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCEEEEECCHHCCCCCEEEEEEEECCC
EADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGD
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
VLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNE
EEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LRHVLDLLHKQF
HHHHHHHHHHCC
>Mature Secondary Structure
MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAK
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VEAALDEIRTILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCEEEEECCHHCCCCCEEEEEEEECCC
EADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGD
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
VLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNE
EEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LRHVLDLLHKQF
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]