Click here to switch to the map view.

The map label for this gene is inlJ [H]

Identifier: 226222956

GI number: 226222956

Start: 354884

End: 356740

Strand: Reverse

Name: inlJ [H]

Synonym: Lm4b_00348

Alternate gene names: 226222956

Gene position: 356740-354884 (Counterclockwise)

Preceding gene: 226222968

Following gene: 226222950

Centisome position: 12.25

GC content: 34.46

Gene sequence:

>1857_bases
ATGAAACTGTCCAAATTTTTTACAATAATTGCATTAAGTGCCACCGTTACAAGTAGCCTACCGATACCAATGGTAAAAGC
AGAGAGCACAACCGCAAATGAAACTAAAATCGAAAATCAATTACCAAAAACAGATTTAAAAGAAACACCGAAAGAAAAAA
CAACGAATAACAACCTGAAAAATCAACTTGTCCAAGCAGGAACCAAAACTTATAATGATTACTTTCCAGATGATAATTTA
GCTAAAGCGGTAGCAGAAAAAATGAACAAAAACGTGGATGAATCTGTAACTGTCGAGGAATTAGCTAAAATAACTAAACT
AGATGCACGGAGCCAAGGCATAGAAGATAGCACTGGAATCGAATATTTGACTGGATTAGAGATACTTTATCTTGAGGATA
ATCAACTAAAAAGTATAGATGTCAGTAAAAATCTAAATCTAAAAGACTTGGCTTGCTCTAACAACCCGTTAGCGAATTTA
GATGTTAGTAAAAATCTTGCTTTAGAAGAATTGACTTGTGAAAACAATGAATTAACACAACTAGATGTTAGCAAAAATAC
AGCTTTAGAGTATTTGTATTGCCCTAGAAATCAGTTAACAAAGCTAGATGTTAGTAAAAACTCCGCTTTACGTTATTTGG
CTTGCGATGTCAATCAGTTAACCAGTTTAGATGTTAGTCAAAATCCAGCTTTAACAAATCTTGGTTGTACTAAAAACCAA
CTTACAGATTTAGATGTTAGCCAAAATCCGAATTTAAGCACTTTGGTTTGTTCTGATAACCAGTTAACCAACTTAGACGT
TAGCCAAAATCAAGCTCTAGCATATTTGACTTGTGATAACAATGGGTTGAAGAATATAGATATTGATCAAAATCTAGCTT
TAATAGAGTTATCTTGTGAAAACAATCAACTAACGAATTTAGATACTACCCAAAATCTAGCTTTAGAGATTTTATATTGC
GATGACAATCAGCTAACGAATTTAGATGTTAGAAAAAACGTAAATTTATTAATTTTATCTTGTAATAACAATCAACTAAC
GAATCTAGCTGTTGGAGAGACAATATTGGATGTAAGCTGTAATAATAACCAGTTAAAAGATATTAGTTCCTTACCAGATT
ATCTTACTGCTGAGAATGGCGAGTACCAAGCAATGGATCAAACATTAGTAGGTCCAATCCAAACGACACAAAATAATACA
CTTGTATACGCTGTTCCTACAGACCTGTTAGATAAGGATGGTAACATTGTTTCCATCATAAAACCAGAAAATGGTGGGGT
TTATGATGCAGCTACTAGAACTATTACGTGGGAAAATTTACCAGATAGCGGAGAAGTGAGTTACACATTTGAAAGCAATG
ACTATGGTGTGTTTTCTGGAAGAGTTACTGTGCCATATACAGGAAAAGAAACTGTCAGCATTTCTAGTGATGATGAGATT
AGTTACAAAGAAGGCACTACAAAAACAGAGGAAGCCTTCCTCACAGATATCCATGCAAGCGTAACTCCAGCAACAGAAAC
CATCACTAGCAATTTTGCTGACGTAGTAGACTTACAAACACCAGGTAAATATGTTGTAACACTAAGCGTGGCAGAATCAG
ATATTACGAAAGACGTCATTGTGTATGTGACAGAGGAACCAAGTAAAGATAATCCTGTCGCTCCTGTTCCACCAAAAGAT
CCAGATAACAAAGTAGCAGACAATGACCAAAATACGGAAAAACCCCAAGTAAAAGTAGACGAAAAGACGTTGCCAAAAAC
AGGTGATATTACTAGCTTAAGTTTGTCATTGGCTGGAATTATTTGCTTAAGCTTTGGTATTCTATTTTTCATCAAACGAA
AGAAAAAAACAGTTTAA

Upstream 100 bases:

>100_bases
GGTAGTTTCTATATAAAATCTCATCTTCACGTGCTAATATATATTTTGTTTGAACACTGCTGACTATACTAAACAACAGC
AACTGAAGGAGCAACTAACT

Downstream 100 bases:

>100_bases
TAATGAGTAATAGCCTTATCATAAGTGATAAGGCTATTTTTTATTCTATCAATATCTACTTTTCAGATTACTTATTGGCA
AAAAAATACAGTCAAAAAGC

Product: internalin, peptidoglycan bound protein (LPXTG motif)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKTDLKETPKEKTTNNNLKNQLVQAGTKTYNDYFPDDNL
AKAVAEKMNKNVDESVTVEELAKITKLDARSQGIEDSTGIEYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANL
DVSKNLALEELTCENNELTQLDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVNQLTSLDVSQNPALTNLGCTKNQ
LTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYLTCDNNGLKNIDIDQNLALIELSCENNQLTNLDTTQNLALEILYC
DDNQLTNLDVRKNVNLLILSCNNNQLTNLAVGETILDVSCNNNQLKDISSLPDYLTAENGEYQAMDQTLVGPIQTTQNNT
LVYAVPTDLLDKDGNIVSIIKPENGGVYDAATRTITWENLPDSGEVSYTFESNDYGVFSGRVTVPYTGKETVSISSDDEI
SYKEGTTKTEEAFLTDIHASVTPATETITSNFADVVDLQTPGKYVVTLSVAESDITKDVIVYVTEEPSKDNPVAPVPPKD
PDNKVADNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGIICLSFGILFFIKRKKKTV

Sequences:

>Translated_618_residues
MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKTDLKETPKEKTTNNNLKNQLVQAGTKTYNDYFPDDNL
AKAVAEKMNKNVDESVTVEELAKITKLDARSQGIEDSTGIEYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANL
DVSKNLALEELTCENNELTQLDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVNQLTSLDVSQNPALTNLGCTKNQ
LTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYLTCDNNGLKNIDIDQNLALIELSCENNQLTNLDTTQNLALEILYC
DDNQLTNLDVRKNVNLLILSCNNNQLTNLAVGETILDVSCNNNQLKDISSLPDYLTAENGEYQAMDQTLVGPIQTTQNNT
LVYAVPTDLLDKDGNIVSIIKPENGGVYDAATRTITWENLPDSGEVSYTFESNDYGVFSGRVTVPYTGKETVSISSDDEI
SYKEGTTKTEEAFLTDIHASVTPATETITSNFADVVDLQTPGKYVVTLSVAESDITKDVIVYVTEEPSKDNPVAPVPPKD
PDNKVADNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGIICLSFGILFFIKRKKKTV
>Mature_618_residues
MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKTDLKETPKEKTTNNNLKNQLVQAGTKTYNDYFPDDNL
AKAVAEKMNKNVDESVTVEELAKITKLDARSQGIEDSTGIEYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANL
DVSKNLALEELTCENNELTQLDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVNQLTSLDVSQNPALTNLGCTKNQ
LTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYLTCDNNGLKNIDIDQNLALIELSCENNQLTNLDTTQNLALEILYC
DDNQLTNLDVRKNVNLLILSCNNNQLTNLAVGETILDVSCNNNQLKDISSLPDYLTAENGEYQAMDQTLVGPIQTTQNNT
LVYAVPTDLLDKDGNIVSIIKPENGGVYDAATRTITWENLPDSGEVSYTFESNDYGVFSGRVTVPYTGKETVSISSDDEI
SYKEGTTKTEEAFLTDIHASVTPATETITSNFADVVDLQTPGKYVVTLSVAESDITKDVIVYVTEEPSKDNPVAPVPPKD
PDNKVADNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGIICLSFGILFFIKRKKKTV

Specific function: Involved in several steps of L.monocytogenes infection [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 MucBP domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR009459
- InterPro:   IPR019931
- InterPro:   IPR001899 [H]

Pfam domain/function: PF06458 MucBP [H]

EC number: NA

Molecular weight: Translated: 67843; Mature: 67843

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKTDLKETPKEKTTNNNLK
CCHHHEEEEEEEEEHHCCCCCCCEEECCCCCCCHHHHHHCCCCCCHHHCCCHHCCCCHHH
NQLVQAGTKTYNDYFPDDNLAKAVAEKMNKNVDESVTVEELAKITKLDARSQGIEDSTGI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANLDVSKNLALEELTCENNELTQ
EEECCEEEEEEECCCEEEEECCCCCCCEEEECCCCCCEECCCCCCCEEEEEECCCCCEEE
LDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVNQLTSLDVSQNPALTNLGCTKNQ
EECCCCCCEEEEECCCCCCEEEECCCCCCEEEEEECCHHHEECCCCCCCCEEECCCCCCC
LTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYLTCDNNGLKNIDIDQNLALIELSCE
CEECCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECC
NNQLTNLDTTQNLALEILYCDDNQLTNLDVRKNVNLLILSCNNNQLTNLAVGETILDVSC
CCCCCCCCCCCCEEEEEEEECCCCEECEEEECCCCEEEEECCCCCEEEEEECCEEEEEEC
NNNQLKDISSLPDYLTAENGEYQAMDQTLVGPIQTTQNNTLVYAVPTDLLDKDGNIVSII
CCCCHHHHHHCCHHHCCCCCCEEECCHHHCCCEEECCCCEEEEEECHHHHCCCCCEEEEE
KPENGGVYDAATRTITWENLPDSGEVSYTFESNDYGVFSGRVTVPYTGKETVSISSDDEI
ECCCCCEEECCEEEEEECCCCCCCCEEEEEECCCEEEEECEEEEEECCCCEEEECCCCCE
SYKEGTTKTEEAFLTDIHASVTPATETITSNFADVVDLQTPGKYVVTLSVAESDITKDVI
EECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHEEEECCCCCEEEEEEECCCCCCCEEE
VYVTEEPSKDNPVAPVPPKDPDNKVADNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGI
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEHHHHHHH
ICLSFGILFFIKRKKKTV
HHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MKLSKFFTIIALSATVTSSLPIPMVKAESTTANETKIENQLPKTDLKETPKEKTTNNNLK
CCHHHEEEEEEEEEHHCCCCCCCEEECCCCCCCHHHHHHCCCCCCHHHCCCHHCCCCHHH
NQLVQAGTKTYNDYFPDDNLAKAVAEKMNKNVDESVTVEELAKITKLDARSQGIEDSTGI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EYLTGLEILYLEDNQLKSIDVSKNLNLKDLACSNNPLANLDVSKNLALEELTCENNELTQ
EEECCEEEEEEECCCEEEEECCCCCCCEEEECCCCCCEECCCCCCCEEEEEECCCCCEEE
LDVSKNTALEYLYCPRNQLTKLDVSKNSALRYLACDVNQLTSLDVSQNPALTNLGCTKNQ
EECCCCCCEEEEECCCCCCEEEECCCCCCEEEEEECCHHHEECCCCCCCCEEECCCCCCC
LTDLDVSQNPNLSTLVCSDNQLTNLDVSQNQALAYLTCDNNGLKNIDIDQNLALIELSCE
CEECCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECC
NNQLTNLDTTQNLALEILYCDDNQLTNLDVRKNVNLLILSCNNNQLTNLAVGETILDVSC
CCCCCCCCCCCCEEEEEEEECCCCEECEEEECCCCEEEEECCCCCEEEEEECCEEEEEEC
NNNQLKDISSLPDYLTAENGEYQAMDQTLVGPIQTTQNNTLVYAVPTDLLDKDGNIVSII
CCCCHHHHHHCCHHHCCCCCCEEECCHHHCCCEEECCCCEEEEEECHHHHCCCCCEEEEE
KPENGGVYDAATRTITWENLPDSGEVSYTFESNDYGVFSGRVTVPYTGKETVSISSDDEI
ECCCCCEEECCEEEEEECCCCCCCCEEEEEECCCEEEEECEEEEEECCCCEEEECCCCCE
SYKEGTTKTEEAFLTDIHASVTPATETITSNFADVVDLQTPGKYVVTLSVAESDITKDVI
EECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHEEEECCCCCEEEEEEECCCCCCCEEE
VYVTEEPSKDNPVAPVPPKDPDNKVADNDQNTEKPQVKVDEKTLPKTGDITSLSLSLAGI
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEHHHHHHH
ICLSFGILFFIKRKKKTV
HHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]