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The map label for this gene is mtnU [H]

Identifier: 226222918

GI number: 226222918

Start: 313527

End: 314306

Strand: Reverse

Name: mtnU [H]

Synonym: Lm4b_00310

Alternate gene names: 226222918

Gene position: 314306-313527 (Counterclockwise)

Preceding gene: 226222919

Following gene: 226222917

Centisome position: 10.79

GC content: 38.97

Gene sequence:

>780_bases
ATGTGGAAGTTGGCATTATGTCAAACTGATGTAGTTTTTAAATATCCTGATGCAAACTATGCACGGATTGAAAAAGCTAT
AGTTGAAGCTGCAAAAAATGGGGCAGATATCGCAGTTTTACCAGAAATGTGGAATACAGGTTATGCTTTAAATGAATTAG
CTGGGGTTGCTGATTTAAATGGGGAGAGAACGAAAGAATTTTTAGCAACACTTTCTGAAAAACACCAAATTGCTATTATC
GGTGGCTCGGTCTCTATTTCGGAAGGAACCAAATTTTCTAATACAATGTATGCTTTCGACAAATATGGTGGACTACTTTC
TTCATATAAGAAGGTTCACTTATTTCAGCTTATGAATGAGCATCTCTATTTAGAGGCTGGGAATGATAAAAATCTATTTC
GACTGGACGGTGTTTCTTGCGCTGGTTTCATTTGCTATGATATTAGATTTCCAGAATGGATTCGCAAACACACTTCAGAA
GGATCGGAAGTCATTTTTGTTTCAGCTCAGTGGCCAGCCGAACGTGTTACTCAGTGGGAGCAACTACTTATTGCACGCGC
TATTGAAAATCAAGCTTTTGTCGTTGCAGTCAATCGAGTTGGCGATGATCCTAATAATCATTTCAATGGGCACTCACTTG
TGATTGATCCACTTGGAAATATTGTCGCTCATGGCGGTGAAGACGAAGGAAATATTTATGCTGAGATTGACTTAAAACTT
GTTGCTGAAACGCGAGGCATCATTCCAGTTTTCACAGATAGACGACCTGAGCTTTACTAA

Upstream 100 bases:

>100_bases
AAAAAGATTAATTCACTACTTAGAGCTTGGTGCGAAGTGTTCCAATATGGACTCGTCACCAAGCTTGTGTTATTTTTAAA
AGAAAAAGGGAGCGAAGAAC

Downstream 100 bases:

>100_bases
ATAGCTAAAAGATGCAAAATAATATTTTTTGCATCTTTTTCTCATTAAATGTTCATATTATCGGCAAAAAAGTGGCAATT
TGGTATAATTAATATAGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MWKLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALNELAGVADLNGERTKEFLATLSEKHQIAII
GGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQLMNEHLYLEAGNDKNLFRLDGVSCAGFICYDIRFPEWIRKHTSE
GSEVIFVSAQWPAERVTQWEQLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKL
VAETRGIIPVFTDRRPELY

Sequences:

>Translated_259_residues
MWKLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALNELAGVADLNGERTKEFLATLSEKHQIAII
GGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQLMNEHLYLEAGNDKNLFRLDGVSCAGFICYDIRFPEWIRKHTSE
GSEVIFVSAQWPAERVTQWEQLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKL
VAETRGIIPVFTDRRPELY
>Mature_259_residues
MWKLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALNELAGVADLNGERTKEFLATLSEKHQIAII
GGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQLMNEHLYLEAGNDKNLFRLDGVSCAGFICYDIRFPEWIRKHTSE
GSEVIFVSAQWPAERVTQWEQLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKL
VAETRGIIPVFTDRRPELY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=272, Percent_Identity=32.7205882352941, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI297632348, Length=278, Percent_Identity=30.9352517985612, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031947, Length=278, Percent_Identity=30.9352517985612, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI297632350, Length=278, Percent_Identity=30.9352517985612, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786412, Length=253, Percent_Identity=33.201581027668, Blast_Score=134, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17556280, Length=265, Percent_Identity=33.9622641509434, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323383, Length=274, Percent_Identity=29.5620437956204, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=31.021897810219, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17933642, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28958; Mature: 28958

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALNELAGVADLN
CEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCCCCC
GERTKEFLATLSEKHQIAIIGGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQLMNE
CHHHHHHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEHHHHCHHHHHHHHHHHHHHHCC
HLYLEAGNDKNLFRLDGVSCAGFICYDIRFPEWIRKHTSEGSEVIFVSAQWPAERVTQWE
EEEEEECCCCCEEEECCCCEEEEEEEECCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
QLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKL
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCEEEEEEEEE
VAETRGIIPVFTDRRPELY
EECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MWKLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALNELAGVADLN
CEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCCCCC
GERTKEFLATLSEKHQIAIIGGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQLMNE
CHHHHHHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEHHHHCHHHHHHHHHHHHHHHCC
HLYLEAGNDKNLFRLDGVSCAGFICYDIRFPEWIRKHTSEGSEVIFVSAQWPAERVTQWE
EEEEEECCCCCEEEECCCCEEEEEEEECCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
QLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKL
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCEEEEEEEEE
VAETRGIIPVFTDRRPELY
EECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]