Click here to switch to the map view.

The map label for this gene is bglC [H]

Identifier: 226222907

GI number: 226222907

Start: 301693

End: 303129

Strand: Reverse

Name: bglC [H]

Synonym: Lm4b_00299

Alternate gene names: 226222907

Gene position: 303129-301693 (Counterclockwise)

Preceding gene: 226222908

Following gene: 226222906

Centisome position: 10.41

GC content: 40.78

Gene sequence:

>1437_bases
ATGGAACATCAAAAACGTTCACCATTCCCGAAAGATTTCTTATGGGGTTCTGCATCGGCAGCTTATCAAATCGAAGGCGC
ATGGGACGCAGACGGCAAAGGTAAATCAGTTTGGGACGAATATGTCCGCATTCCTGGAACTACTTTTAAAGGTACAAATG
GCGATGTAGCTGTCGACCATTATCACCGTTATAAAGAAGACGTAAAACTAATGGCAGACGCTGGCCTAAAAGCTTACCGT
TTCTCTATCGCTTGGACTCGTATTTTTCCAAATGGTAAAGGCGAAGTGAATGAAGCTGGATTGAAATTTTATGATAACTT
GATTGATGAGTTGCTTAAATATGACATTGAACCGCTTGTAACGCTTTATCACTGGGATATCCCACAAGCATTATTTGATG
AATACGGTGGCTGGGAATCTCGCCAAGTTATTGAAGATTTCACAAATTATTCCACAACGCTATTCAAACGTTACGGCGAC
CGCGTGAAATATTGGGTTTCCTTGAATGAGCAAAATATCTTTGTTGGTATGGGTTATGGTCAAGCGCTTCACCCGCCAAA
AGTTAGCGATCCAAAAAGAATGTACGCAGTAAACCATATTGCGAACTTAGCTAATGCGAGTGTTATCAAAGCTTTCCACG
AAATCGTTCCTGATGGAAAAATTGGACCAAGTTTTGCTTACACACCACATTATCCAATCGACACAGATCCTAAAAACGTT
CAAGCTGCCGACGATGCAGAAGAATTAAACAGTTATTTCTGGATGGATATGTATGCTTTTGGGCGCTATCCGAAAGCGGT
TTGGAAATATTTAGAAGAAAACGATATTGCGCCAGTTATTGAAGACGGCGATATGGAACTTCTTGCTTCTGCAAAACCAG
ATTTCATGGGCGTAAACTATTACCAATCCGCAACTGTTGCTTACAACCCGCTTGATGGCGTTGGTCAAAACAACGAAATG
AACTTCACTGGTAAAAAAGGTAGCACGAAAGAGACTGGTGTTCCTGGCGTTTACAAAAAAGTCGTTAATCCTTTTGTGAA
AACAACGAACTGGGACTGGACAATCGATCCAAAAGGCTTACAAATTGCGCTTCGTCGTATTAACAGCCGCTATGCTTTAC
CAATTTTAATTACAGAAAACGGTTTAGGTGAATTTGATAAATTAGTTGATGGTGAAGTAAACGATGACTACCGTATTGAC
TATCTAAGCGCGCACGCAACTGCTATTCGCGATGCAATCAGTGATGGCGTTGATATGTTAGGCTATTGTACTTGGAGCTT
CACAGACCTTCTAAGCTGGTTAAACGGCTATCAAAAACGTTACGGTTTTGTTTATGTTGACCGCGATGTGGAAGATGATG
CGCCAATGACACGTATTCCGAAGAAAAGTTATTATTGGTATAAACAAGTGATTGAAACTAATGGAGCAGATTTATAA

Upstream 100 bases:

>100_bases
ATAGGAATCTGCGTTTTTTAACTATCTTTTTAAAAGAATATACTTTAAAATATATTAGTAGAGTTTTTTAATAAAAATCG
CTTTAATGGAGGTTATATTA

Downstream 100 bases:

>100_bases
ATGATGGCTGACCTTCAAGATTGGCTAGCTAGAATCCAAGCAAAAATCACTGCGTTAAAAGAAAAAGATCCCGATTTGAA
TTTATTTGGTTCAGAAAGCC

Product: phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MEHQKRSPFPKDFLWGSASAAYQIEGAWDADGKGKSVWDEYVRIPGTTFKGTNGDVAVDHYHRYKEDVKLMADAGLKAYR
FSIAWTRIFPNGKGEVNEAGLKFYDNLIDELLKYDIEPLVTLYHWDIPQALFDEYGGWESRQVIEDFTNYSTTLFKRYGD
RVKYWVSLNEQNIFVGMGYGQALHPPKVSDPKRMYAVNHIANLANASVIKAFHEIVPDGKIGPSFAYTPHYPIDTDPKNV
QAADDAEELNSYFWMDMYAFGRYPKAVWKYLEENDIAPVIEDGDMELLASAKPDFMGVNYYQSATVAYNPLDGVGQNNEM
NFTGKKGSTKETGVPGVYKKVVNPFVKTTNWDWTIDPKGLQIALRRINSRYALPILITENGLGEFDKLVDGEVNDDYRID
YLSAHATAIRDAISDGVDMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDVEDDAPMTRIPKKSYYWYKQVIETNGADL

Sequences:

>Translated_478_residues
MEHQKRSPFPKDFLWGSASAAYQIEGAWDADGKGKSVWDEYVRIPGTTFKGTNGDVAVDHYHRYKEDVKLMADAGLKAYR
FSIAWTRIFPNGKGEVNEAGLKFYDNLIDELLKYDIEPLVTLYHWDIPQALFDEYGGWESRQVIEDFTNYSTTLFKRYGD
RVKYWVSLNEQNIFVGMGYGQALHPPKVSDPKRMYAVNHIANLANASVIKAFHEIVPDGKIGPSFAYTPHYPIDTDPKNV
QAADDAEELNSYFWMDMYAFGRYPKAVWKYLEENDIAPVIEDGDMELLASAKPDFMGVNYYQSATVAYNPLDGVGQNNEM
NFTGKKGSTKETGVPGVYKKVVNPFVKTTNWDWTIDPKGLQIALRRINSRYALPILITENGLGEFDKLVDGEVNDDYRID
YLSAHATAIRDAISDGVDMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDVEDDAPMTRIPKKSYYWYKQVIETNGADL
>Mature_478_residues
MEHQKRSPFPKDFLWGSASAAYQIEGAWDADGKGKSVWDEYVRIPGTTFKGTNGDVAVDHYHRYKEDVKLMADAGLKAYR
FSIAWTRIFPNGKGEVNEAGLKFYDNLIDELLKYDIEPLVTLYHWDIPQALFDEYGGWESRQVIEDFTNYSTTLFKRYGD
RVKYWVSLNEQNIFVGMGYGQALHPPKVSDPKRMYAVNHIANLANASVIKAFHEIVPDGKIGPSFAYTPHYPIDTDPKNV
QAADDAEELNSYFWMDMYAFGRYPKAVWKYLEENDIAPVIEDGDMELLASAKPDFMGVNYYQSATVAYNPLDGVGQNNEM
NFTGKKGSTKETGVPGVYKKVVNPFVKTTNWDWTIDPKGLQIALRRINSRYALPILITENGLGEFDKLVDGEVNDDYRID
YLSAHATAIRDAISDGVDMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDVEDDAPMTRIPKKSYYWYKQVIETNGADL

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=484, Percent_Identity=33.0578512396694, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=31.0699588477366, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI13273313, Length=488, Percent_Identity=31.3524590163934, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI28376633, Length=479, Percent_Identity=30.062630480167, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI24497614, Length=492, Percent_Identity=29.2682926829268, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=45.360824742268, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI2367174, Length=498, Percent_Identity=38.9558232931727, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI2367270, Length=484, Percent_Identity=38.4297520661157, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1789070, Length=496, Percent_Identity=37.9032258064516, Blast_Score=314, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17552856, Length=485, Percent_Identity=30.7216494845361, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17539390, Length=495, Percent_Identity=28.2828282828283, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356577, Length=496, Percent_Identity=32.258064516129, Blast_Score=244, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54582; Mature: 54582

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHQKRSPFPKDFLWGSASAAYQIEGAWDADGKGKSVWDEYVRIPGTTFKGTNGDVAVDH
CCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEECCCCCCEEHHH
YHRYKEDVKLMADAGLKAYRFSIAWTRIFPNGKGEVNEAGLKFYDNLIDELLKYDIEPLV
HHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
TLYHWDIPQALFDEYGGWESRQVIEDFTNYSTTLFKRYGDRVKYWVSLNEQNIFVGMGYG
EEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCC
QALHPPKVSDPKRMYAVNHIANLANASVIKAFHEIVPDGKIGPSFAYTPHYPIDTDPKNV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QAADDAEELNSYFWMDMYAFGRYPKAVWKYLEENDIAPVIEDGDMELLASAKPDFMGVNY
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCEECCCE
YQSATVAYNPLDGVGQNNEMNFTGKKGSTKETGVPGVYKKVVNPFVKTTNWDWTIDPKGL
ECCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHH
QIALRRINSRYALPILITENGLGEFDKLVDGEVNDDYRIDYLSAHATAIRDAISDGVDML
HHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCHHHH
GYCTWSFTDLLSWLNGYQKRYGFVYVDRDVEDDAPMTRIPKKSYYWYKQVIETNGADL
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEHQKRSPFPKDFLWGSASAAYQIEGAWDADGKGKSVWDEYVRIPGTTFKGTNGDVAVDH
CCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEECCCCCCEEHHH
YHRYKEDVKLMADAGLKAYRFSIAWTRIFPNGKGEVNEAGLKFYDNLIDELLKYDIEPLV
HHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
TLYHWDIPQALFDEYGGWESRQVIEDFTNYSTTLFKRYGDRVKYWVSLNEQNIFVGMGYG
EEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCC
QALHPPKVSDPKRMYAVNHIANLANASVIKAFHEIVPDGKIGPSFAYTPHYPIDTDPKNV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QAADDAEELNSYFWMDMYAFGRYPKAVWKYLEENDIAPVIEDGDMELLASAKPDFMGVNY
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCEECCCE
YQSATVAYNPLDGVGQNNEMNFTGKKGSTKETGVPGVYKKVVNPFVKTTNWDWTIDPKGL
ECCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHH
QIALRRINSRYALPILITENGLGEFDKLVDGEVNDDYRIDYLSAHATAIRDAISDGVDML
HHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCHHHH
GYCTWSFTDLLSWLNGYQKRYGFVYVDRDVEDDAPMTRIPKKSYYWYKQVIETNGADL
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]