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The map label for this gene is adcA [H]

Identifier: 226222787

GI number: 226222787

Start: 151040

End: 151981

Strand: Direct

Name: adcA [H]

Synonym: Lm4b_00153

Alternate gene names: 226222787

Gene position: 151040-151981 (Clockwise)

Preceding gene: 226222785

Following gene: 226222788

Centisome position: 5.19

GC content: 39.38

Gene sequence:

>942_bases
ATGAAAAAATGGTCATTTTTAGTTGTAACAGTGTTGGCGTTCGTTTTAGTTTTGGCCGGATGCGGTGCTAGCAACAATAA
AGTAAGTGGAGATAAGGACAAGCTCAAGGTAGTGACAACTTTTTATCCAATGTACGATTTTACGAAAAATGTTGCGGGAG
ATAATGCTTCCATTGAAATGTTGATTGATGCGGGGACAGAACCGCATGATTACGAGCCAAGCGCAAAGGATATTGCCAAA
ATCGAAGCGGCTGATGTTTTCGTTTATAACAGTGAAGACATGGAAACTTGGGTGCCGAGCGTACTTAAAAGCTTAGATTC
GAAAAAATTAACCGTGATTGACGCGAGTAAAGGAATCGAGCTAGTAGAAGGAACCGAAGAAGAAGACCATGATCATGAGC
ACGAAGAAGGACACCACCATGAACATGATCCTCACGTATGGCTAAGCCCAGTCCTTGCCGAACAAGAAGTGACTAATATC
CAGAACGGTCTTACAAAAGCAGATAAAACAAATGCAGATACATACAAAAAGAACGCAGAAACATATAAAGAGAAATTAAA
AACACTCGACAACAAATTTAAAACAGCTTTTGAAGGAGCAAAACAACGCGATTTCGTAACCCAACATGCAGCCTTCCAAT
ATTTAGCAAAAGAGTATGACTTGCATCAAGTGGCAATCGCCGGCCTTTCACCTGACCAAGAACCAAGCCCAGCACGATTA
GCGGAATTACAAAAATACGTGAAAGAAAATAATATCAGCACCATTTATTTTGAAGAAGTAGCTTCACCAAAAGTTGCAGA
AACACTTGCAAACGAAACGGGAGCAAAACTAGAAGTACTAAGCCCTATCGAAGGAATTACGGATAAAGAACAGAAAAAAG
GCATGGATTATATTGCTTATATGGAACAAAACTTACAAGCCTTGCAAAAAACAATAAAATAA

Upstream 100 bases:

>100_bases
GTGCAAATAAGAATGATTACGTTTTGCGATGCGCAATCATAATTTACATAGTGTAACTTTAAGTTTTAAATCGTAATCAT
TACGAAAAAGGAGAGGTAAT

Downstream 100 bases:

>100_bases
GGAAGCGATCAAATGAAATACATCGATATAGCCAATATTGGTTTTAAATACGAATCCGAACCAGTGCTTGAAAACATTTC
TTTTCAAGTGAGTGCGGGAG

Product: a probable high-affinity zinc ABC transporter (Zn(II)-binding lipoprotein)

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKKWSFLVVTVLAFVLVLAGCGASNNKVSGDKDKLKVVTTFYPMYDFTKNVAGDNASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIELVEGTEEEDHDHEHEEGHHHEHDPHVWLSPVLAEQEVTNI
QNGLTKADKTNADTYKKNAETYKEKLKTLDNKFKTAFEGAKQRDFVTQHAAFQYLAKEYDLHQVAIAGLSPDQEPSPARL
AELQKYVKENNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMEQNLQALQKTIK

Sequences:

>Translated_313_residues
MKKWSFLVVTVLAFVLVLAGCGASNNKVSGDKDKLKVVTTFYPMYDFTKNVAGDNASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIELVEGTEEEDHDHEHEEGHHHEHDPHVWLSPVLAEQEVTNI
QNGLTKADKTNADTYKKNAETYKEKLKTLDNKFKTAFEGAKQRDFVTQHAAFQYLAKEYDLHQVAIAGLSPDQEPSPARL
AELQKYVKENNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMEQNLQALQKTIK
>Mature_313_residues
MKKWSFLVVTVLAFVLVLAGCGASNNKVSGDKDKLKVVTTFYPMYDFTKNVAGDNASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIELVEGTEEEDHDHEHEEGHHHEHDPHVWLSPVLAEQEVTNI
QNGLTKADKTNADTYKKNAETYKEKLKTLDNKFKTAFEGAKQRDFVTQHAAFQYLAKEYDLHQVAIAGLSPDQEPSPARL
AELQKYVKENNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMEQNLQALQKTIK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=259, Percent_Identity=21.6216216216216, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35055; Mature: 35055

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWSFLVVTVLAFVLVLAGCGASNNKVSGDKDKLKVVTTFYPMYDFTKNVAGDNASIEM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEHHHHHHHHHCCCCCCEEEE
LIDAGTEPHDYEPSAKDIAKIEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIE
EEECCCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCE
LVEGTEEEDHDHEHEEGHHHEHDPHVWLSPVLAEQEVTNIQNGLTKADKTNADTYKKNAE
ECCCCCCCCCCCCHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TYKEKLKTLDNKFKTAFEGAKQRDFVTQHAAFQYLAKEYDLHQVAIAGLSPDQEPSPARL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHH
AELQKYVKENNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAY
HHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHHH
MEQNLQALQKTIK
HHHHHHHHHHHCC
>Mature Secondary Structure
MKKWSFLVVTVLAFVLVLAGCGASNNKVSGDKDKLKVVTTFYPMYDFTKNVAGDNASIEM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEHHHHHHHHHCCCCCCEEEE
LIDAGTEPHDYEPSAKDIAKIEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIE
EEECCCCCCCCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCE
LVEGTEEEDHDHEHEEGHHHEHDPHVWLSPVLAEQEVTNIQNGLTKADKTNADTYKKNAE
ECCCCCCCCCCCCHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TYKEKLKTLDNKFKTAFEGAKQRDFVTQHAAFQYLAKEYDLHQVAIAGLSPDQEPSPARL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHH
AELQKYVKENNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAY
HHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHHH
MEQNLQALQKTIK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]