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The map label for this gene is nanB [H]

Identifier: 225861513

GI number: 225861513

Start: 1547513

End: 1549606

Strand: Reverse

Name: nanB [H]

Synonym: SPT_1625

Alternate gene names: 225861513

Gene position: 1549606-1547513 (Counterclockwise)

Preceding gene: 225861514

Following gene: 225861512

Centisome position: 73.37

GC content: 33.29

Gene sequence:

>2094_bases
ATGAATAAAAGAGGTCTTTATTCAAAACTAGGAATTTCTGTTGTAGGCATTAGTCTTTTAATGGGAGTCCCCACTTTGAT
TCATGCGAATGAATTAAACTATGGTCAACTGTCCATATCTCCTATTTTTCAAGGAGGTTCATATCAACTGAACAATAAGA
GTATAGATATCAGCCCTTTGTTATTAGATAAATTGTCTGGAGAGAGTCAGACAGTAGTAATGAAATTTAAAGCAGATAAA
CCAAACTCTCTTCAAGCTTTGTTTGGCCTATCTAATAGTAAAGCAGGTTTTAAAAATAATTACTTTTCAATTTTCATGAG
AGATTCTGGTGAGATAGGTGTAGAAATAAGAGACGCCCAAAAGGGAATAAATTATTTATTTTCTAGACCAGCTTCATTAT
GGGGAAAGCATAAAGGACAGGCAGTTGAAAATACACTAGTATTTGTATCTGATTCTAAAGATAAAACATACACAATGTAT
GTTAATGGAATAGAAGTGTTCTCTGAAACAGTTGATACATTTTTGCCAATTTCAAATATAAATGGTATAGATAAGGCAAC
ACTAGGAGCTGTTAATCGTGAAGGTAAGGAACATTACCTCGCAAAAGGAAGTATTGATGAAATCAGTCTATTTAACAAAG
CAATTAGTGATCAGGAAGTTTCAAATATTCCCTTGTCAAATCCCTTTCAGTTAATTTTCCAATCAGGAGATTCTACTCAA
GCTAACTATTTTAGAATACCGACACTATATACATTAAGTAGTGGAAGAGTTCTATCAAGTATTGATGCACGTTATGGTGG
GACTCATGATTCTAAAAGTAAGATTAATATTGCCACTTCTTATAGTGATGATAATGGGAAAACGTGGAGTGAGCCAATTT
TTGCTATGAAGTTTAATGACTATGAGGAGCAGTTAGTTTACTGGCCACGAGATAATAAATTAAAGAATAGTCAAATTAGT
GGAAGTGCTTCATTCATAGATTCATCCATTGTTGAAGATAAAAAATCTGGGAAAACGATATTACTAGCTGATGTTATGCC
TGCGGGTATTGGAAATAATAATGCAAATAAAGCCGACTCAGGTTTTAAAGAAATAAATGGTCATTATTATTTAAAACTAA
AGAAGAATGGAGATAACGATTTCCGTTATACAGTTAGAGAAAATGGTGTCGTTTATGATGAAACAACTAATAAACCTACA
AATTATACTATAAATGATAAGTATGAAGTTTTGGAGGGAGGAAAGTCTTTAACAGTCGAACAATATTCGGTTGATTTTGA
TAGTGGCTCTTTAAGAGAAAGGCATAATGGAAAACAGGTTCCTATGAATGTTTTCTACAAAGATTCGTTATTTAAAGTGA
CTCCTACTAATTATATAGCAATGACAACTAGTCAGAATAGAGGAGAGAGTTGGGAACAATTTAAGTTGTTGCCTCCGTTC
TTAGGAGAAAAACATAATGGAACTTACTTGTGTCCTGGACAAGGTTTAGCATTAAAATCAAGTAACAGATTGATTTTTGC
AACATATACTAGTGGAGAACTAACCTATCTCATTTCTGATGATAGTGGTCAAACATGGAAGAAATCCTCAGCTTCAATTC
CGTTTAAAAATGCAACAGCAGAAGCACAAATGGTTGAACTGAGAGATGGTGTGATTAGAACATTCTTTAGAACCACTACA
GGTAAGATAGCTTATATGACTAGTAGAGATTCTGGAGAAACATGGTCGGAAGTTTCGTATATTGATGGAATCCAACAAAC
TTCATATGGCACACAAGTATCTGCAATTAAATACTCTCAATTAATTGATGGAAAAGAAGCAGTCATTTTGAGTACACCAA
ATTCTAGAAGTGGCCGTAAGGGAGGTCAATTAGTTGTCGGTTTAGTCAATAAAGAAGATGATAGTATTGATTGGAAATAC
CACTATGATATTGATTTGCCTTCGTATGGTTATGCCTATTCTGCGATTACAGAATTGCCAAATCATCACATAGGTGTACT
GTTTGAAAAATATGATTCGTGGTCGAGAAATGAATTGCATTTAAGCAATGTAGTTCAGTATATAGATTTGGAAATTAATG
ATTTAACAAAATAA

Upstream 100 bases:

>100_bases
TTGTAGTTCTTCCATCAATTATTTTCTTCTCTATCATCCAAAATAAGATTGCAAGTGGATTATCAGAAGGATCTGTGAAG
TAGACGAAAGAAGGAAAAAA

Downstream 100 bases:

>100_bases
AGGAGAAAAAACATGGTTAAATACGGTGTTGTTGGAGCAGGGTATTTTGGAGCTGAATTGGCTCGCTATATGCAAAAGAA
TGATGGAGCAGAGATTACTC

Product: sialidase B (Neuraminidase B)

Products: NA

Alternate protein names: Neuraminidase B [H]

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADK
PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQ
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS
GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT
NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT
GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY
HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK

Sequences:

>Translated_697_residues
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADK
PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQ
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS
GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT
NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT
GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY
HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
>Mature_697_residues
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADK
PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQ
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS
GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT
NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT
GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY
HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK

Specific function: Unknown

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 BNR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 77721; Mature: 77721

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPL
CCCCCCHHHHCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCEEECCCCEECCHH
LLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQ
HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECHH
KGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNI
HHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCC
NGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQ
CCCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFND
CCEEECCEEEEECCCCEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECC
YEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADS
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
GFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVE
CHHHCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHEECCCCEEEEE
QYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
EEEEECCCCCCHHHCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCHHEEECCHH
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATA
HCCCCCCCEEECCCCEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
EAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQ
CHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCHHCCCCCEEEEEEHHH
LIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELP
HCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHCC
NHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
CCCEEEEEEECCCCCCCEEEHHHHEEEEEEEECCCCC
>Mature Secondary Structure
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPL
CCCCCCHHHHCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCEEECCCCEECCHH
LLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQ
HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECHH
KGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNI
HHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCC
NGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQ
CCCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFND
CCEEECCEEEEECCCCEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECC
YEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADS
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
GFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVE
CHHHCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHEECCCCEEEEE
QYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
EEEEECCCCCCHHHCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCHHEEECCHH
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATA
HCCCCCCCEEECCCCEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
EAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQ
CHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCHHCCCCCEEEEEEHHH
LIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELP
HCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHCC
NHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
CCCEEEEEEECCCCCCCEEEHHHHEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759848; 11463916 [H]