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The map label for this gene is manR [H]

Identifier: 225861451

GI number: 225861451

Start: 1481373

End: 1482836

Strand: Reverse

Name: manR [H]

Synonym: SPT_1561

Alternate gene names: 225861451

Gene position: 1482836-1481373 (Counterclockwise)

Preceding gene: 225861452

Following gene: 225861450

Centisome position: 70.21

GC content: 35.93

Gene sequence:

>1464_bases
GTGTCTAGAAAACAAGAACAAATGGAAACGTTGTTGCTCCTTTTGCGAGATAGTAAGGATTATATATCTGCTAAAGTATT
GGGAGAAAAATTAAATTGCTCTGATAAAACGGTTTATCGCCTTGTCAAGGTAATCAACAAAGATTGTCCGGTAGAAGCAT
TCATTTTATCTGAAAAAGGCAGAGGCTTCAAATTAAATCCAAGAAGTTCCCTCGTGGACGTTGATGGGAATTTTACAGAG
GCTTTTGATCCTGAAGTAAGGCGTGAAAAATTACTAGAACGTCTCTTGTTGACTGCTCCTAAGCCACATTCTATTTATGA
TTTAGGAGAGGAATTCTACGTAAGCGAGTCAGTAGTACTAAAAGATCGTCAGATATTACAAGAGAGTCTAGCAATTTATG
GGTTAGATTTAAAAATGAGACAACGAAAGCTTTTTATTGATGGGGATGAGGCTCAAATTCGTTCAGCCATTCTAAATCTA
CTGCCAATGTTTAATCAGTTGGATTTAGAGCAAATTACACAGAATAAGGTTCAGCCTCTTGACGGAGAACTTGCTCACTT
TTGTTTGGGATTACTGATTACACTTGAGAGAGAATTGGGGGTAAACATTCCCTATCCATATAATATAAATATTTTCTCTC
ACCTGTATATTTTTATCAGTAGGAATCGTCGTAGTACTAGTATTCATGTTGTAGCACCTTCAAAACCTACTATTGTTGAT
GAGAAAATTTACAGTGTCTGTCAAAAAATTATTCAAGAAATTGAACAATATTTTAAGATGAAGGTTGATGCAGTTGAGAT
TGACTATCTTTATCAATACGTTGTATCTTCGAGATTGCAAAAACCATTTTCTTCCGGGAAGCTTCCTTTTTCTCAGCGAG
TTTTAGATGTCACTCATTACTATTTTAGCCGTATGTGTATGGACAATAGAGAGATTGAAACGACAGATCCTGACTTTGTT
GACTTGGCGAGTCATATCAGTCCCTTACTGAGGAGATTAGATAATAGAGTACAGATTAAGAATAGTCTTTTATCACAAAT
TCTTTTAACCTATCCTAATCTGGTTAAAGAGTTAACAACTATTTCTAAAGAAGTGAGTCTAGTATTTGGTTTTGCGTCCT
TGAGTCTGGACGAGATTGGTTTTCTAGTCTTATATTTTGCACGGTTTCAAGAAAAGCGAGCACGTCCTCTAAAAACAGTA
GTGATGTGTACATCAGGTGTCGGAACTTCAGAGCTTTTACGAGCACGATTAGAAAAGCAATTTACTGAATTGGATATTAT
TGATGTAGTTGCTTATCATCAATTAGATGAGCTGATAAATCTATATCCAGATTTAGATTTCATTGTGACGACGGTAGCTT
TGCAGGAACCAGCAAGTGTCCCGTTTGTCCTAGTTAGTGTTTTTCTAACCGAGGGTGATAAACAACGTCTTCAAGCAAAA
ATTCAGGAGATAAACTATGAATAA

Upstream 100 bases:

>100_bases
CATATTTTTGATAAAAACAAAAATGTCCATTGCAAAGGACAAAATGCGAAGTATATTATTTTTTGAAAGCGATATAATGG
AATCATAAAGGAGGTGTATC

Downstream 100 bases:

>100_bases
TCTTTCGCTTGTCCTTATGGATATATCTGTTCAAAATCGTCAAGAAGCCTACAAAGAATTAGCAAATCAAATCAGCCTTC
TTGTTTCTGAAGATACAGAA

Product: putative transcription antiterminator BglG family protein

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKVINKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTE
AFDPEVRREKLLERLLLTAPKPHSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIFISRNRRSTSIHVVAPSKPTIVD
EKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVSSRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFV
DLASHISPLLRRLDNRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEKRARPLKTV
VMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVTTVALQEPASVPFVLVSVFLTEGDKQRLQAK
IQEINYE

Sequences:

>Translated_487_residues
MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKVINKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTE
AFDPEVRREKLLERLLLTAPKPHSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIFISRNRRSTSIHVVAPSKPTIVD
EKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVSSRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFV
DLASHISPLLRRLDNRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEKRARPLKTV
VMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVTTVALQEPASVPFVLVSVFLTEGDKQRLQAK
IQEINYE
>Mature_486_residues
SRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKVINKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEA
FDPEVRREKLLERLLLTAPKPHSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNLL
PMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIFISRNRRSTSIHVVAPSKPTIVDE
KIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVSSRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVD
LASHISPLLRRLDNRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEKRARPLKTVV
MCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVTTVALQEPASVPFVLVSVFLTEGDKQRLQAKI
QEINYE

Specific function: May regulate the expression of the mannose operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 56146; Mature: 56015

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKVINKDCPVEAFILSEKG
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
RGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKPHSIYDLGEEFYVSESVVL
CCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCHHHH
KDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNLLPMFNQLDLEQITQNKVQPL
HHHHHHHHHHHHCCCCCEECCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
DGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIFISRNRRSTSIHVVAPSKPTIVD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECCCCCCEEEEECCCCCCCHH
EKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVSSRLQKPFSSGKLPFSQRVLDVTHY
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
YFSRMCMDNREIETTDPDFVDLASHISPLLRRLDNRVQIKNSLLSQILLTYPNLVKELTT
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKEVSLVFGFASLSLDEIGFLVLYFARFQEKRARPLKTVVMCTSGVGTSELLRARLEKQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHHHHH
FTELDIIDVVAYHQLDELINLYPDLDFIVTTVALQEPASVPFVLVSVFLTEGDKQRLQAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
IQEINYE
HHHCCCC
>Mature Secondary Structure 
SRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKVINKDCPVEAFILSEKG
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
RGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKPHSIYDLGEEFYVSESVVL
CCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCHHHH
KDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNLLPMFNQLDLEQITQNKVQPL
HHHHHHHHHHHHCCCCCEECCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
DGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIFISRNRRSTSIHVVAPSKPTIVD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECCCCCCEEEEECCCCCCCHH
EKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVSSRLQKPFSSGKLPFSQRVLDVTHY
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
YFSRMCMDNREIETTDPDFVDLASHISPLLRRLDNRVQIKNSLLSQILLTYPNLVKELTT
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKEVSLVFGFASLSLDEIGFLVLYFARFQEKRARPLKTVVMCTSGVGTSELLRARLEKQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHHHHH
FTELDIIDVVAYHQLDELINLYPDLDFIVTTVALQEPASVPFVLVSVFLTEGDKQRLQAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
IQEINYE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]