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The map label for this gene is pncA [H]

Identifier: 225861414

GI number: 225861414

Start: 1450685

End: 1451260

Strand: Reverse

Name: pncA [H]

Synonym: SPT_1522

Alternate gene names: 225861414

Gene position: 1451260-1450685 (Counterclockwise)

Preceding gene: 225861415

Following gene: 225861413

Centisome position: 68.71

GC content: 39.58

Gene sequence:

>576_bases
ATGACAAAGGCTTTAATTTCGATTGATTATACAGAAGATTTTGTTGCTGATAGTGGGAAACTAACAGCAGGTGCTCCAGC
TCAGGCGATTTCGGATGCCATCAGCAAGGTAACTCGATTAGCTTTTGAACGAGGAGATTATATCTTCTTTACTATTGATG
CTCATGAAGAAAACGATTGTTTCCATCCGGAAAGTAAGTTATTTCCTCCTCATAATCTGATTGGGACGAGTGGACGGAAT
TTATATGGAGATTTGGGGATCTTTTATCAAGAGCATGGTTCAGACAGTCGTGTCTTTTGGATGGATAAACGCCATTACTC
AGCTTTTTCAGGGACTGACCTAGATATTCGTTTGAGAGAGCGTAGAGTGTCTACCGTTATCTTAACAGGTGTCTTGACGG
ATATCTGTGTCCTACATACAGCTATAGATGCCTATAATCTAGGATATGACATCGAGATTGTTAAACCAGCTGTTGCTTCC
ATCTGGCCTGAAAATCATCAATTTGCCCTAGGTCATTTCAAAAATACACTCGGAGCTAAGTTAGTAGATGAAAATCTAAA
TGAACTTTCTGAGTAA

Upstream 100 bases:

>100_bases
CTGCGGGGATTATTGAAAGTCGCTCACTTGGAATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAA
GTGAAGAAAAGAGATTACTA

Downstream 100 bases:

>100_bases
CCTGGTTGGTGAAAATGAAAAAATTTGAAAAAAAGTGTTGACAAGCATCCCAAAAGTTGATATACTAGTAAAGTAATCGA
CGCGGGGATGGCGGAATTGG

Product: isochorismatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRN
LYGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
IWPENHQFALGHFKNTLGAKLVDENLNELSE

Sequences:

>Translated_191_residues
MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRN
LYGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
IWPENHQFALGHFKNTLGAKLVDENLNELSE
>Mature_190_residues
TKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNL
YGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVASI
WPENHQFALGHFKNTLGAKLVDENLNELSE

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

Organism=Escherichia coli, GI87081992, Length=88, Percent_Identity=36.3636363636364, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 21369; Mature: 21238

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDC
CCCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
FHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRE
CCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHH
RRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVASIWPENHQFALGHFKNTLGAK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCEEEHHHHHHHHHHH
LVDENLNELSE
HHHHHHHHHCC
>Mature Secondary Structure 
TKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDC
CCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
FHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRE
CCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHH
RRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVASIWPENHQFALGHFKNTLGAK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCEEEHHHHHHHHHHH
LVDENLNELSE
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]