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The map label for this gene is fabG [H]

Identifier: 225861303

GI number: 225861303

Start: 1340818

End: 1341516

Strand: Reverse

Name: fabG [H]

Synonym: SPT_1406

Alternate gene names: 225861303

Gene position: 1341516-1340818 (Counterclockwise)

Preceding gene: 225861304

Following gene: 225861302

Centisome position: 63.51

GC content: 44.92

Gene sequence:

>699_bases
ATGACTAAACGTGTACTCATTACAGGAGTGAGTTCAGGGATCGGATTGGCTCAAGCTCGCCTCTTTTTAGAGAAGGGCTA
TCAAGTTTATGGAGTTGACCAAGGTGAAAAGCCACTCTTAGAGGGTGATTTTCACTTTTTACAGAGAGATTTGACCTTGG
ACTTGGAACCTATTTTTGACTGGTGCCCTCAGGTGGATGTTTTGTGTAATACTGCTGGAGTTTTGGATGATTACAAACCA
CTGTTGGAACAAACGGCGCAGGACATTCAAGAGATTTTTGAAATCAACTACATTATTCCAGTAGAGTTGACTCGGTATTA
TTTGACACAAATGCTGGAAAATAAAAAGGGAATCATCATCAATATGTGTTCCATTGCTTCTAGCCTAGCAGGTGGAGGTG
GTCACGCCTATACTTCATCCAAGCATGCCTTGGCTGGCTTCACCAAGCAGTTGGCTCTAGACTATGCTGAAGCTGGGATT
CAGGTCTTTGGTATCGCTCCAGGAGCAGTCAAGACAGCTATGACCGCTGCGGATTTTGAACCAGGTGGTTTGGCTGACTG
GGTGGCTAGTGAAACCCCAATCAAGCGCTGGATTGAGCCAGAGGAAATAGCAGAGCTTAGTCTTTTTTTAGCAAGTGGAA
AAGCGAGCGCCATGCAAGGACAAATCTTGACAATAGATGGTGGCTGGTCTTTGAAGTAG

Upstream 100 bases:

>100_bases
ACACCTTATTTCCTAATCAACGTTTCTGGCGAAGGAGAAGGTTTTTCCATGTGGAGCCCGACAGTTTGTGATGTTTTGGC
AACGGATTGGGTAGAAGTGC

Downstream 100 bases:

>100_bases
GAGGAGTTGGATGGAAATCAAAAAACACTTTGGAGTCTACGCTGTTTGCTTAGAAAATGGGAAGTTACTCTGCATTGAAA
AAACGAGAGGCCCTTATCAA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDFHFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKP
LLEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK

Sequences:

>Translated_232_residues
MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDFHFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKP
LLEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK
>Mature_231_residues
TKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDFHFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPL
LEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGIQ
VFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=221, Percent_Identity=28.9592760180996, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=26.9709543568465, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=27.0491803278689, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4758504, Length=251, Percent_Identity=26.2948207171315, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542939, Length=216, Percent_Identity=28.2407407407407, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=31.9672131147541, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=29.6747967479675, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=31.404958677686, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=31.1965811965812, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=32.0987654320988, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=31.1203319502075, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=26.1224489795918, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.4615384615385, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=28.7937743190661, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=30.6513409961686, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=27.8008298755187, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=26.9387755102041, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.277566539924, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.8387096774194, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=29.9610894941634, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=27.6679841897233, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=168, Percent_Identity=30.3571428571429, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=213, Percent_Identity=29.5774647887324, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=31.2757201646091, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=30.9917355371901, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=27.2, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358495, Length=228, Percent_Identity=26.7543859649123, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25249; Mature: 25118

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDFHFLQRDLTLDLEPIFD
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHH
WCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIII
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCEEE
NMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGIQVFGIAPGAVKTAMTAADFE
EHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
PGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK
CCCCHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHCCEEEEECCCCCCC
>Mature Secondary Structure 
TKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDFHFLQRDLTLDLEPIFD
CCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHH
WCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIII
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCEEE
NMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGIQVFGIAPGAVKTAMTAADFE
EHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
PGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK
CCCCHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]