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The map label for this gene is insK [H]

Identifier: 225861286

GI number: 225861286

Start: 1320322

End: 1321155

Strand: Reverse

Name: insK [H]

Synonym: SPT_1385

Alternate gene names: 225861286

Gene position: 1321155-1320322 (Counterclockwise)

Preceding gene: 225861287

Following gene: 225861283

Centisome position: 62.55

GC content: 36.45

Gene sequence:

>834_bases
ATGACTGAGTTTTCGTTAGATATTCTTCTAAAAGCCATTAAACTAGCTCGTTCGACCTACTACTATCACTTGAAACAGCT
AGATAAAACAGATAAGGACCAAGAGCTTAAAGCTGAAATTCAATCCATTTTTATCGAACACAAGGGAAATTATGCTTATC
GTCGGATTTATTTAGAACTAAGAAATCGTGGTTATCTGGTAAATCATAAAAGAGTTCAAGGCTTGATAAAAGTACTCAAT
TTACAAGCTAAAATGCGACAAAAACGAAAATATTCTTCTCATAAAGGAGACGTTGGTAAGAAAGCAGAGAATCTCATTCA
AGGCCAATTTGAAGGCTCTAAAACAATGGAAAAGTGCTACACAGATGTGACAGAATTTGCCATTCCAGCAAGTACTCAAA
AGCTTTACTTATTACCAGTTTTAGATGGCTTTAATAGCGAAATTATCGCCTATAATCTTTCAACTTCACCCAACTTAGAA
CAAGTACAAACAATGTTGGAACAGGCATTCAAAGAGAAGCACTACGAGAATACGATTCTCCATAGTGACCAAGGCTGGCA
ATATCAACACGATTCTTATCATCAGTTTCTTGAGGGTAAGGGAATTCAAGCATCCATGTCACGTAAGGGTAACAGCCCAG
ACAATGGTATGATGGAGTCCTTCTTTGGGATTCTGAAATCGGAAATGTTTTACGGTTATGAGAAGTCGTTTCAGTCGCTT
AAGCAATTGGAACAAGCCATTGTAGACTATATTGATTACTACAACAATAAACGAATTAAGGTAAAACTAAAAGGACTTAG
CCCTGTGCAATACAGAACTAAATCCTTCGGATAA

Upstream 100 bases:

>100_bases
AGTACCTGAGAGCGGAAAATGCCATCCTAAAAAAGTTAAGAGAACTCCGATTGAAGGAGGAAAAAGAGAAAGAAGAAAGA
CAGAAATTGTTCAAGAATTA

Downstream 100 bases:

>100_bases
ATTAATTGTCTAACTTTTTGGGGTCAGTACAAAACTCTTGCTACTATGCGTTTTATTATTGAAAGACTTATTGGACTTTC
TCTCAAATCGAGTTTTTACT

Product: integrase core domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTEFSLDILLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLIKVLN
LQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLLPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFKEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSL
KQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Sequences:

>Translated_277_residues
MTEFSLDILLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLIKVLN
LQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLLPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFKEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSL
KQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
>Mature_276_residues
TEFSLDILLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLIKVLNL
QAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLLPVLDGFNSEIIAYNLSTSPNLEQ
VQTMLEQAFKEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSLK
QLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=235, Percent_Identity=29.7872340425532, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=48.1751824817518, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=28.7234042553192, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32388; Mature: 32257

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFSLDILLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEEEH
RNRGYLVNHKRVQGLIKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCY
HCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPASTQKLYLLPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFKEKHYENTIL
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
HSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSL
ECCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
TEFSLDILLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLEL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEEEH
RNRGYLVNHKRVQGLIKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCY
HCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPASTQKLYLLPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFKEKHYENTIL
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
HSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSL
ECCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]