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The map label for this gene is fruR [H]

Identifier: 225861233

GI number: 225861233

Start: 1267138

End: 1267878

Strand: Reverse

Name: fruR [H]

Synonym: SPT_1326

Alternate gene names: 225861233

Gene position: 1267878-1267138 (Counterclockwise)

Preceding gene: 225861234

Following gene: 225861232

Centisome position: 60.03

GC content: 41.84

Gene sequence:

>741_bases
GTGTTAAAAACAGAACGTAAACAACTAATTTTAGAGGAGTTAAATCAACATCATGTAGTTTCTCTAGAAAAATTAGTTAG
TTTGCTAGAAACGTCAGAATCAACGGTTCGAAGAGACTTGGATGAGTTGGAAGCGGAAAACAAGCTTCGTCGTGTGCATG
GTGGAGCAGAACTCCCCTACTCCTTACAGGAAGAAGAAACCATTCAAGAAAAATCTGTCAAAAACCTTCAAGAAAAGAAA
TTGCTGGCTCAGAAAGCAGCCTCTCTCATTAAAGAAAAAGATGTCATCTTTATCGATGCTGGAACAACAACTGCTTTTTT
GATTCATGAATTGGTCAATAAGAATGTTACAGTTGTGACCAACTCCATTCACCATGCCGCTCAGTTGGTTGAAAAGCAGA
TTCCAACTGTCATGGTTGGAGGAAACGTCAAGACGGCGACAGATGCTAGTATCGGGGGCGTTGCTCTTAACCAGATTAAC
CAATTGCACTTTGACCGTGCCTTTATCGGAATAAATGGTGTTGACGATGGCTATTATACGACTCCTGATATGGAGGAGGG
AGCTGTGAAAAGAGCTATTTTGGAGAATGCCAAGCAGACCTACGTCTTGGTGGATTCGTCAAAAATTGGACAAACTTGCT
TTGCCAAGGTAGCCCCACTCAAACGCGCTATCGTTATCACTAGTCAAGGGCATGAGCTCTTGCAGGTTATTAAGGAGAAA
ACGGAGGTAATAGAAGTATGA

Upstream 100 bases:

>100_bases
GAAAAAATGATAGATTTTGAAAGAAAATGATAAAAAATGCTTGACTTCGAAAGAAAGTATGATAGAATGAATAGTGTAAA
CGATAACAGGAGGTGATTCA

Downstream 100 bases:

>100_bases
TTTATACAGTCACACTCAATCCATCCATTGACTATATCGTTCGTTTGGACCAAGTCAAAGTTGGTAGTGTCAATCGTATG
GACAGTGATGATAAGTTTGC

Product: lactose phosphotransferase system repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELEAENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKK
LLAQKAASLIKEKDVIFIDAGTTTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVAPLKRAIVITSQGHELLQVIKEK
TEVIEV

Sequences:

>Translated_246_residues
MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELEAENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKK
LLAQKAASLIKEKDVIFIDAGTTTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVAPLKRAIVITSQGHELLQVIKEK
TEVIEV
>Mature_246_residues
MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELEAENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKK
LLAQKAASLIKEKDVIFIDAGTTTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVAPLKRAIVITSQGHELLQVIKEK
TEVIEV

Specific function: Repressor Of The Glycerol-3-Phosphate Regulon. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=224, Percent_Identity=34.375, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI226510968, Length=223, Percent_Identity=31.390134529148, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787540, Length=220, Percent_Identity=34.0909090909091, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789059, Length=214, Percent_Identity=30.8411214953271, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789519, Length=234, Percent_Identity=29.4871794871795, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=28.5123966942149, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=26.4069264069264, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788069, Length=245, Percent_Identity=26.9387755102041, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790753, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082344, Length=192, Percent_Identity=28.125, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787063, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27286; Mature: 27286

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELEAENKLRRVHGGAELPY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGTTTAFLIHELVNKNVTVVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEE
NSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQINQLHFDRAFIGINGVDDGYYT
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCC
TPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVAPLKRAIVITSQGHELLQVIKEK
CCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHH
TEVIEV
HHHHCC
>Mature Secondary Structure
MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELEAENKLRRVHGGAELPY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGTTTAFLIHELVNKNVTVVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEE
NSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQINQLHFDRAFIGINGVDDGYYT
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCC
TPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVAPLKRAIVITSQGHELLQVIKEK
CCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHH
TEVIEV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]