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The map label for this gene is yhdH [H]

Identifier: 225860715

GI number: 225860715

Start: 715482

End: 716813

Strand: Reverse

Name: yhdH [H]

Synonym: SPT_0753

Alternate gene names: 225860715

Gene position: 716813-715482 (Counterclockwise)

Preceding gene: 225860716

Following gene: 225860712

Centisome position: 33.94

GC content: 42.12

Gene sequence:

>1332_bases
ATGGTTTTCTTGACAGACCTTAGAAAACATAATAGGATAGTCAAGTCTATCAATCAAACAGAAGGCTATTTGACAACTCA
AGTAGCTTTTTCTTATTTTGAAAAAGGAGATCAGAGTTTAACTATGTCAGAAAAATCACAATGGGGGTCGAAACTTGGCT
TTATTCTAGCATCTGCTGGCTCGGTCATCGGGCTTGGTTCCGTTTGGAAGTTTCCCTACATGACTGCTGCTAATGGCGGT
GGAGGCTTTTTACTAATCTTTCTCATTTCCACTATTTTAATCGGTTTCCCTCTCCTGCTGGCTGAGTTTGCCCTTGGCCG
TAGTGCTGGCGTTTCCGCTATCAAAACCTTTGGAAAACTGGGCAAGAATAACAAGTACAACTTTATCGGTTGGATTGGCG
CCTTTGCCCTCTTTATCCTCTTATCTTTTTACAGTGTTATCGGAGGATGGATTCTAGTCTATCTAGGTATTGAGTTTGGG
AAATTGTTCCAACTTGGTGGAACGGGTGATTATGCTCAGTTATTTACTTCAATCATTTCAAATCCAGCCATTGCCCTAGT
AGCTCAAGCAGCCTTTATCTTATTAAATATCTTTATTGTATCACGTGGGGTTCAAAAAGGGATTGAAAGAGCTTCGAAAG
TCATGATGCCCCTGCTCTTTATCATCTTTGTTGTTATCATCGGTCGCTCTCTCAGTTTGCCAAATGCCATGGAAGGGGTT
CTTTACTTCCTCAAACCAGACTTTTCAAAACTGACTAGCGCTGGTCTCCTCTATGCTCTGGGACAATCTTTCTTTGCCCT
CTCACTAGGGGTTACAGTCATGATGCCCCTGCTCTTTATCGTCTTACCTCAACTCTTTGACAAGATGCCTTTTGGAACCA
TTTTCTACGTCCTCTTCCTCTTTGCGACTGTCACTTCTTCTGTCGTGATGCTGGAGATCAATGTGGGCAATATCACCAAC
CAGGATAACAGCAAACGTGCCAAATGGAGTGTTATTTTAGGAATTTTGACCTTTGTCTTTGGCATTCCTTCAGCCCTATC
TTACGGTGTCATGGCGGATGTTCACATTTTTGGTAAGATCTTCTTTGACGCTATGGACTTCTTGGCTTCCAATCTCCTCA
TGCCATTTGGAGCTCTCTACCTTTCACTTTTTACAGGCTATATCTTTAAAAAGGCTCTTGCAATGGAGGAACTCCATCTC
GATGAAAGAGCATGGAAACAAGGACTGTTCCAAGTCTGGCTCTTCCTTCTTCGTTTCTTCGTTTCGTCATTCCAATCATC
ATCATTGTGGTCTTCATTGCCCAATTTATGTAATCAAAAAGGACTTGAGTAG

Upstream 100 bases:

>100_bases
TTCTTTTATATGGTACATGATTTCCTCCTTACAATGATAGTATAACCCCTCCCCTTAGGTCAGAGTTAAGCGTTTTTGAG
AAAGGTGTGAAAACTTGAAA

Downstream 100 bases:

>100_bases
TGAACTCAGGCCCTTTCTTTTTATGGATGGCTAACAATCAATTCCAAACCTTGCCCTTCCAGAGTCCAAGCTTCAACATC
ACTTGGTAGGATAAAGTGTC

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMPLLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITN
QDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHL
DERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE

Sequences:

>Translated_443_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMPLLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITN
QDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHL
DERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE
>Mature_443_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMPLLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITN
QDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHL
DERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=275, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI21361581, Length=286, Percent_Identity=25.1748251748252, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI7657587, Length=283, Percent_Identity=25.4416961130742, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI58219014, Length=275, Percent_Identity=26.9090909090909, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI188528618, Length=273, Percent_Identity=25.6410256410256, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI33354281, Length=128, Percent_Identity=35.15625, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI21361693, Length=128, Percent_Identity=35.9375, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI171184408, Length=277, Percent_Identity=24.9097472924188, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI171184406, Length=277, Percent_Identity=24.9097472924188, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI171184404, Length=277, Percent_Identity=24.9097472924188, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI51468073, Length=257, Percent_Identity=26.0700389105058, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI92859670, Length=310, Percent_Identity=24.8387096774194, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI194018524, Length=265, Percent_Identity=26.7924528301887, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507041, Length=297, Percent_Identity=24.5791245791246, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI197276623, Length=276, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI54607094, Length=276, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI134304856, Length=292, Percent_Identity=25, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI5032097, Length=290, Percent_Identity=25.1724137931034, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI218563756, Length=290, Percent_Identity=25.1724137931034, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI11181770, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI289191351, Length=281, Percent_Identity=25.2669039145907, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4557046, Length=281, Percent_Identity=25.2669039145907, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI289191377, Length=279, Percent_Identity=25.4480286738351, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI67782313, Length=100, Percent_Identity=34, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI67782317, Length=75, Percent_Identity=41.3333333333333, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI67782315, Length=75, Percent_Identity=41.3333333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI197276625, Length=118, Percent_Identity=33.0508474576271, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=115, Percent_Identity=37.3913043478261, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17554804, Length=276, Percent_Identity=27.8985507246377, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI133952791, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146584, Length=293, Percent_Identity=24.2320819112628, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=113, Percent_Identity=31.858407079646, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542050, Length=120, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364394, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28574704, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136950, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28574702, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762620, Length=276, Percent_Identity=25.7246376811594, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136952, Length=280, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24661428, Length=284, Percent_Identity=27.4647887323944, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281365034, Length=275, Percent_Identity=26.9090909090909, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363702, Length=271, Percent_Identity=28.0442804428044, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363700, Length=271, Percent_Identity=28.0442804428044, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921352, Length=281, Percent_Identity=24.1992882562278, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584353, Length=281, Percent_Identity=24.1992882562278, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639853, Length=295, Percent_Identity=23.3898305084746, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655079, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221329674, Length=256, Percent_Identity=26.953125, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639516, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24639514, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281364136, Length=289, Percent_Identity=24.2214532871972, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551183, Length=113, Percent_Identity=35.3982300884956, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550877, Length=113, Percent_Identity=35.3982300884956, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654186, Length=119, Percent_Identity=32.7731092436975, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582567, Length=255, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48875; Mature: 48875

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAG
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
SVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKL
CEEECCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHC
NPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMPLLFIVLPQLFDKMPFGTIFYVLFL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKI
HHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHLDERAWKQGLFQVWLFLLRFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFQSSSLWSSLPNLCNQKGLE
HHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAG
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
SVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKL
CEEECCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHC
NPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMPLLFIVLPQLFDKMPFGTIFYVLFL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKI
HHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHLDERAWKQGLFQVWLFLLRFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFQSSSLWSSLPNLCNQKGLE
HHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]