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The map label for this gene is adcA [H]

Identifier: 225859941

GI number: 225859941

Start: 2112474

End: 2113979

Strand: Reverse

Name: adcA [H]

Synonym: SP70585_2295

Alternate gene names: 225859941

Gene position: 2113979-2112474 (Counterclockwise)

Preceding gene: 225859942

Following gene: 225859939

Centisome position: 96.76

GC content: 42.76

Gene sequence:

>1506_bases
GTGAAAAAAATTAGCTTATTACTAGCCAGTCTATGTGCCTTGTTTTTAGTGGCTTGTTCCAATCAAAAACAGGCAGATGG
TAAACTCAATATCGTGACAACCTTTTACCCTGTCTATGAATTTACCAAGCAAGTCGCAGGAGATACGGCTAATGTAGAAC
TCCTAATCGGTGCTGGGACAGAACCTCATGAATACGAACCATCTGCCAAGGCAGTTGCCAAAATCCAAGATGCAGATACC
TTCGTTTATGAAAATGAAAACATGGAAACATGGGTACCTAAATTGCTAGATACCTTGGATAAGAAAAAAGTGAAAACCAT
CAAGGCGACAGGCGATATGTTGCTCTTGCCAGGTGGCGAGGAAGAAGAGGGAGACCATGACCATGGAGAAGAAGGTCATT
ACCATGAGTTTGACCCCCATGTTTGGTTATCACCAGTTCGTGCCATTAAACTAGTAGAGCACATTCGTGACAGCTTGTCA
GCAGATTATCCTGATAAAAAAGAGACCTTTGAGAAGAATGCAGCTGCCTATATCGAAAAATTGCAAGCCTTGGATAAGGC
TTACGCAGAAGGCTTGTCTCAAGCAAAACAAAAGAGCTTTGTGACTCAACACGCAGCCTTTAACTATCTTGCCTTGGACT
ATGGACTCAAACAAGTCGCAATCTCAGGACTTTCTCCAGATGCAGAGCCATCAGCTGCTCGCTTGGCAGAATTGACAGAG
TATGTCAAGAAAAATAAAATCGCCTATATCTATTTTGAAGAAAATGCCTCACAAGCCCTTGCTAACACACTTTCAAAAGA
AGCAGGTGTCAAAACTGATGTCCTCAATCCTTTAGAAAGTCTGACAGAAGAGGACACCAAGGCTGGAGAAAACTACATTT
CCGTGATGGAGAAAAACCTCAAGGCTTTGAAACAAACAACAGACCAAGAAGGCCCAGCAATCGAACCTGAAAAGGCAGAG
GATACCAAGACAGTCCAAAATGGTTACTTCGAGGATGCAGCTGTCAAGGACCGCACCTTGAGTGACTATGCAGGTAACTG
GCAATCAGTTTATCCTTTCCTTGAAGACGGCACGTTTGACCAAGTCTTTGACTACAAGGCTAAGTTGACTGGTAAGATGA
CCCAGGCTGAGTACAAGGCTTACTATACAAAAGGCTATCATACAGATGTGACTAAGATTAACATTACTGATAATACTATG
GAATTTGTTCAAGGTGGACAAAGCAAGAAATACACTTACAAGTATGTCGGTAAGAAAATTTTGACTTACAAGAAAGGCAA
TCGTGGCGTGCGTTTCCTCTTTGAAGCCACAGATGCTGACGCTGGACAATTCAAGTATGTTCAGTTTAGTGACCACAATA
TCGCCCCAGTTAAGGCAGAACATTTCCATATCTTTTTTGGAGGCACAAGCCAAGAAGCCCTCTTTGAAGAAATGGACAAC
TGGCCAACCTACTACCCAGATAACCTATCTGGCCAAGAAATCGCCCAAGAAATGTTGGCGCATTGA

Upstream 100 bases:

>100_bases
CTATGCAGAAACACCTGCAAGTGCAAGTATTACCATTATTTTTGTAACTGTCTTTATACTAATCAGTTTAGTAAGACGTT
TTATCAAATAGGAGACGAAC

Downstream 100 bases:

>100_bases
TGAGAAATCGACTAGTTCATAAGAGCTAGTCGGTTTTTTGATACTAGATGGCTAACTTCATTATAGACCTTTCAGAACTA
AGGAACTTTAAAAAAATAAA

Product: zinc-binding lipoprotein AdcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHYHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH

Sequences:

>Translated_501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHYHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH
>Mature_501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHYHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI1788284, Length=175, Percent_Identity=53.1428571428571, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87081990, Length=258, Percent_Identity=24.031007751938, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 56261; Mature: 56261

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCC
EPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGE
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCC
EEEGDHDHGEEGHYHEFDPHVWLSPVRAIKLVEHIRDSLSADYPDKKETFEKNAAAYIEK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHH
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISVMEKNL
HHHHCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFD
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCHHHHCCCHHHCCHHHCCCCHH
QVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKI
HHHHHHHHHCCCHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHCCHH
LTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDN
EEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEECEEEEEECCCCHHHHHHHHCC
WPTYYPDNLSGQEIAQEMLAH
CCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCC
EPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGE
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCC
EEEGDHDHGEEGHYHEFDPHVWLSPVRAIKLVEHIRDSLSADYPDKKETFEKNAAAYIEK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHH
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISVMEKNL
HHHHCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFD
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCHHHHCCCHHHCCHHHCCCCHH
QVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKI
HHHHHHHHHCCCHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHCCHH
LTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDN
EEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEECEEEEEECCCCHHHHHHHHCC
WPTYYPDNLSGQEIAQEMLAH
CCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]