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The map label for this gene is uidA [H]

Identifier: 225859888

GI number: 225859888

Start: 2050562

End: 2052361

Strand: Reverse

Name: uidA [H]

Synonym: SP70585_2241

Alternate gene names: 225859888

Gene position: 2052361-2050562 (Counterclockwise)

Preceding gene: 225859889

Following gene: 225859887

Centisome position: 93.94

GC content: 40.61

Gene sequence:

>1800_bases
ATGTTGTATCCAATTCAAACGAAAACACGCTCAGTTTATTCTTTAAACGGAATATGGGCCTTTAAGCAAGGAAACAATGA
TGTTCAATCTTTGTTAGATACGGATGAGGTAATGGTTGTACCAAGTTCCTTCAATGATATTGTTGTTGACAAAGAGAAAC
GCCGTTTTGTCGGAGATAATTGGTATGAACTGATGGTGGCTATCCCTGCTGTGTCTGATGATGAAGAATTAGTGGTGCGC
TTTGGCTCCGTGACGCATCAGGCTATGGTCTATGCGGATGGTCAGTTAATCGGGAAGCATAAGGGGGGCTTTACCCCTTT
TGAATGCCTGGTTCCGTCGGAATTATATGGTTTGGATCAATTCCGCCTGACAGTTTGTGCCAATAATGAGCTGAATTATA
CAACCCTTCCAGTAGGGAATTACAGTGAAGAGGTAGATGAAAACGGTCAAATTGTGAAGACGGTCAAGGAAAATTTTGAC
TTTTTCAACTATGCTGGTATTCAGCGGAATGTTCATCTCTATAAACGTCCGAAAAATAGGGTTGATGATATTGTTATTCG
GACTGAACTGAATAATGAATTGACTCAAGCTGTTGTTCATGTTGAGGTGGCGACAGTTGGGCAGTATGATTCTATTCGTA
TTCACATTTTTAATCAAGAAGGACAGGAACTAGGTCTTCTTGAAAATGGACGGATAGTCATTGATAATCCCCGCCTTTGG
GAAGTTTTAGATGCCTATCTCTATACTGCAAAAGTCGAATTATTTGATGGTGAGAGCTTATTAGATACTTACTGCGAACA
GTTTGGTCTTCGTAGTGTTGCAGTTGAGAATGGACAATTTTTCATCAACGGAAAACCGTTCTATTTCAAGGGATTTGGTA
AACATGAAGACACCTTTATCAATGGCCGCGGCTTCAACGAAGCAGCTAATCTGATGGATTTGAACTTACTCAAAGATATT
GGAGCTAATTCATTTAGAACGTCCCATTATCCATATTCTGAAGAAATGATGCGACTGGCAGATCGATTGGGAATTGTAGT
CATTGACGAGGTGCCAGCAGTCGGGCTGTTCCAGCTTTTCAATGCAGCCTTGAATTTGACAGGGGATTCTGATGAGGTAA
AAAATACCTGGGAAGTCATGCAAACCAAGGATGCTCATGAACTAGTGATTGATGAATTGATAGCGCGTGATAAGAACCAT
CCATCCGTAGTGATGTGGGTTGTAGCCAATGAACCGGCAGGGCATGAAAAAGGTGCACGTGCTTACTTTGAACCTCTGAT
TCAGCGAATGAGAGATAGAGATCCTTCTAACCGTCCTGTAACCTTGGTTAATATTATGACGGCAACACCTGATAAAGATG
AAGTTATGGACTTGGTTGATGTTGTCTGTCTCAATCGTTATTATGGTTGGTATGCTGCTCATGGCGACTTGAAGATGGCA
GAAAAAGGACTTCGAAAGGAACTAGAGACATGGCAAGAACTATATCCAGACAAGCCTATTTTGATTACAGAATATGGTGC
AGATACTCTCCCAGGCTTGCATTCAATGTGGGATATTCCTTATACGGAAGAATTTCAAGTGGATTACTATGATATGAATC
ACAGGGTTTTTGATTCTATTTCAAATGTGGTTGGTGAACAAGTCTGGAATTTTGCTGATTTTGAAACCACAGTTGGTCTC
ATTCGGATTCAAGGAAATCATAAGGGTTTATTCTCACGGAATCGTCAACCCAAGCAAATTGTTAGAGAAATAAAGAAACG
TTGGACTGCCATTCCAAACTACCATTATAAAAGGAAATAG

Upstream 100 bases:

>100_bases
ATACCATTGAAGGGGATGTCAATGTCATCAGTCAATCAGATATTGATTTGTTATTGAAAAAAGGGTCTCGTGAAATAAAA
CGATAGAAAGTAGGAAAAAT

Downstream 100 bases:

>100_bases
GCTATAATAGTAGCAAATAGAAAGTTGTATTGGAGGACCAAGCACATGGCGAAACCCTTGGTAGAAAAAGCATCAGAACG
CTTATTGGAATTGATTTTGG

Product: beta-D-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSFNDIVVDKEKRRFVGDNWYELMVAIPAVSDDEELVVR
FGSVTHQAMVYADGQLIGKHKGGFTPFECLVPSELYGLDQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
FFNYAGIQRNVHLYKRPKNRVDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFNQEGQELGLLENGRIVIDNPRLW
EVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVENGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDI
GANSFRTSHYPYSEEMMRLADRLGIVVIDEVPAVGLFQLFNAALNLTGDSDEVKNTWEVMQTKDAHELVIDELIARDKNH
PSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSNRPVTLVNIMTATPDKDEVMDLVDVVCLNRYYGWYAAHGDLKMA
EKGLRKELETWQELYPDKPILITEYGADTLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSISNVVGEQVWNFADFETTVGL
IRIQGNHKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK

Sequences:

>Translated_599_residues
MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSFNDIVVDKEKRRFVGDNWYELMVAIPAVSDDEELVVR
FGSVTHQAMVYADGQLIGKHKGGFTPFECLVPSELYGLDQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
FFNYAGIQRNVHLYKRPKNRVDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFNQEGQELGLLENGRIVIDNPRLW
EVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVENGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDI
GANSFRTSHYPYSEEMMRLADRLGIVVIDEVPAVGLFQLFNAALNLTGDSDEVKNTWEVMQTKDAHELVIDELIARDKNH
PSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSNRPVTLVNIMTATPDKDEVMDLVDVVCLNRYYGWYAAHGDLKMA
EKGLRKELETWQELYPDKPILITEYGADTLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSISNVVGEQVWNFADFETTVGL
IRIQGNHKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK
>Mature_599_residues
MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSFNDIVVDKEKRRFVGDNWYELMVAIPAVSDDEELVVR
FGSVTHQAMVYADGQLIGKHKGGFTPFECLVPSELYGLDQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
FFNYAGIQRNVHLYKRPKNRVDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFNQEGQELGLLENGRIVIDNPRLW
EVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVENGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDI
GANSFRTSHYPYSEEMMRLADRLGIVVIDEVPAVGLFQLFNAALNLTGDSDEVKNTWEVMQTKDAHELVIDELIARDKNH
PSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSNRPVTLVNIMTATPDKDEVMDLVDVVCLNRYYGWYAAHGDLKMA
EKGLRKELETWQELYPDKPILITEYGADTLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSISNVVGEQVWNFADFETTVGL
IRIQGNHKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=630, Percent_Identity=38.2539682539683, Blast_Score=381, Evalue=1e-105,
Organism=Escherichia coli, GI1787903, Length=603, Percent_Identity=45.4394693200663, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1786539, Length=307, Percent_Identity=28.6644951140065, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI48994920, Length=392, Percent_Identity=22.9591836734694, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17510825, Length=623, Percent_Identity=37.7207062600321, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI62471735, Length=631, Percent_Identity=37.7179080824089, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI19922582, Length=631, Percent_Identity=37.7179080824089, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24655438, Length=631, Percent_Identity=37.7179080824089, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24651745, Length=635, Percent_Identity=35.748031496063, Blast_Score=352, Evalue=4e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 68859; Mature: 68859

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSFNDIVVDKEKRRFVGDN
CCCCCCCCCCCEEEECCEEEEECCCHHHHHHHCCCCEEEECCCCCCEEECCHHHHCCCCC
WYELMVAIPAVSDDEELVVRFGSVTHQAMVYADGQLIGKHKGGFTPFECLVPSELYGLDQ
CEEEEEEECCCCCCHHHHEEECCCCEEEEEEECCEEEECCCCCCCCHHEECCHHHCCCCE
FRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFDFFNYAGIQRNVHLYKRPKNR
EEEEEEECCCCCEEEEECCCCHHHHCCCCCEEHHHHHCCCEEEECCCCCCEEEEECCCCC
VDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFNQEGQELGLLENGRIVIDNPRLW
CCCEEEEEECCHHHHHHEEEEEEEECCCCCEEEEEEECCCCCEECEEECCEEEECCCHHH
EVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVENGQFFINGKPFYFKGFGKHEDTFI
HHHHHHHHEEEEEEECCHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEECCCCCCCEEE
NGRGFNEAANLMDLNLLKDIGANSFRTSHYPYSEEMMRLADRLGIVVIDEVPAVGLFQLF
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHH
NAALNLTGDSDEVKNTWEVMQTKDAHELVIDELIARDKNHPSVVMWVVANEPAGHEKGAR
HHHEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHH
AYFEPLIQRMRDRDPSNRPVTLVNIMTATPDKDEVMDLVDVVCLNRYYGWYAAHGDLKMA
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHH
EKGLRKELETWQELYPDKPILITEYGADTLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEECCHHHHHHH
SNVVGEQVWNFADFETTVGLIRIQGNHKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSFNDIVVDKEKRRFVGDN
CCCCCCCCCCCEEEECCEEEEECCCHHHHHHHCCCCEEEECCCCCCEEECCHHHHCCCCC
WYELMVAIPAVSDDEELVVRFGSVTHQAMVYADGQLIGKHKGGFTPFECLVPSELYGLDQ
CEEEEEEECCCCCCHHHHEEECCCCEEEEEEECCEEEECCCCCCCCHHEECCHHHCCCCE
FRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFDFFNYAGIQRNVHLYKRPKNR
EEEEEEECCCCCEEEEECCCCHHHHCCCCCEEHHHHHCCCEEEECCCCCCEEEEECCCCC
VDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFNQEGQELGLLENGRIVIDNPRLW
CCCEEEEEECCHHHHHHEEEEEEEECCCCCEEEEEEECCCCCEECEEECCEEEECCCHHH
EVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVENGQFFINGKPFYFKGFGKHEDTFI
HHHHHHHHEEEEEEECCHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEECCCCCCCEEE
NGRGFNEAANLMDLNLLKDIGANSFRTSHYPYSEEMMRLADRLGIVVIDEVPAVGLFQLF
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHH
NAALNLTGDSDEVKNTWEVMQTKDAHELVIDELIARDKNHPSVVMWVVANEPAGHEKGAR
HHHEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHH
AYFEPLIQRMRDRDPSNRPVTLVNIMTATPDKDEVMDLVDVVCLNRYYGWYAAHGDLKMA
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHH
EKGLRKELETWQELYPDKPILITEYGADTLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEECCHHHHHHH
SNVVGEQVWNFADFETTVGLIRIQGNHKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]