| Definition | Streptococcus pneumoniae 70585, complete genome. |
|---|---|
| Accession | NC_012468 |
| Length | 2,184,682 |
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The map label for this gene is amiE [H]
Identifier: 225859653
GI number: 225859653
Start: 1805794
End: 1806861
Strand: Reverse
Name: amiE [H]
Synonym: SP70585_1946
Alternate gene names: 225859653
Gene position: 1806861-1805794 (Counterclockwise)
Preceding gene: 225859654
Following gene: 225859652
Centisome position: 82.71
GC content: 42.32
Gene sequence:
>1068_bases ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGAATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA AATGGGATTTGCCCATCTGGCTGACTAG
Upstream 100 bases:
>100_bases TTCCATTGACAACCCTTGTCTTGGTATCCTTGTCCCTTTTCGTAGTTGGTCAAAACTTAGCGGATGCTAGTGATCCACGT ACACATAGATAGGAGTAGAA
Downstream 100 bases:
>100_bases GAGGAAGGAAATGTCTGAAAAATTAGTAGAAATCAAAGATTTAGAAATTTCCTTCGGTGAAGGAAGTAAGAAGTTTGTCG CGGTTAAAAATGCTAACTTC
Product: oligopeptide transport ATP-binding protein OppD
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 355; Mature: 354
Protein sequence:
>355_residues MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIANKVAVMYAGEIVE YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD
Sequences:
>Translated_355_residues MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIANKVAVMYAGEIVE YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD >Mature_354_residues TKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLT ALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQYS GGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIANKVAVMYAGEIVEY GTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKT WLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD
Specific function: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI171184400, Length=229, Percent_Identity=33.1877729257642, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI9665248, Length=245, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI9961250, Length=222, Percent_Identity=31.0810810810811, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI9961252, Length=222, Percent_Identity=31.0810810810811, Blast_Score=72, Evalue=9e-13, Organism=Homo sapiens, GI4505771, Length=222, Percent_Identity=31.0810810810811, Blast_Score=72, Evalue=9e-13, Organism=Homo sapiens, GI42741659, Length=242, Percent_Identity=30.5785123966942, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI11967969, Length=243, Percent_Identity=27.9835390946502, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI148612844, Length=252, Percent_Identity=28.1746031746032, Blast_Score=67, Evalue=4e-11, Organism=Homo sapiens, GI255708477, Length=252, Percent_Identity=28.1746031746032, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI21536378, Length=231, Percent_Identity=30.7359307359307, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI156105685, Length=245, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=6e-11, Organism=Escherichia coli, GI48994883, Length=300, Percent_Identity=45, Blast_Score=278, Evalue=5e-76, Organism=Escherichia coli, GI1789963, Length=292, Percent_Identity=46.9178082191781, Blast_Score=271, Evalue=4e-74, Organism=Escherichia coli, GI145693107, Length=269, Percent_Identity=49.0706319702602, Blast_Score=256, Evalue=2e-69, Organism=Escherichia coli, GI1787759, Length=271, Percent_Identity=43.1734317343173, Blast_Score=225, Evalue=4e-60, Organism=Escherichia coli, GI1788506, Length=291, Percent_Identity=41.9243986254296, Blast_Score=216, Evalue=3e-57, Organism=Escherichia coli, GI1787500, Length=302, Percent_Identity=40.3973509933775, Blast_Score=206, Evalue=1e-54, Organism=Escherichia coli, GI1789962, Length=296, Percent_Identity=38.8513513513513, Blast_Score=204, Evalue=1e-53, Organism=Escherichia coli, GI1787548, Length=302, Percent_Identity=34.1059602649007, Blast_Score=184, Evalue=1e-47, Organism=Escherichia coli, GI1787758, Length=268, Percent_Identity=37.3134328358209, Blast_Score=175, Evalue=4e-45, Organism=Escherichia coli, GI1789890, Length=250, Percent_Identity=41.2, Blast_Score=171, Evalue=9e-44, Organism=Escherichia coli, GI48994997, Length=235, Percent_Identity=36.5957446808511, Blast_Score=151, Evalue=8e-38, Organism=Escherichia coli, GI1787547, Length=243, Percent_Identity=34.156378600823, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1789032, Length=237, Percent_Identity=32.9113924050633, Blast_Score=132, Evalue=4e-32, Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=34.9344978165939, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1788225, Length=241, Percent_Identity=34.0248962655602, Blast_Score=124, Evalue=9e-30, Organism=Escherichia coli, GI1786398, Length=250, Percent_Identity=33.6, Blast_Score=124, Evalue=9e-30, Organism=Escherichia coli, GI1787712, Length=251, Percent_Identity=31.8725099601594, Blast_Score=109, Evalue=3e-25, Organism=Escherichia coli, GI1788761, Length=242, Percent_Identity=29.7520661157025, Blast_Score=108, Evalue=7e-25, Organism=Escherichia coli, GI1789672, Length=237, Percent_Identity=30.379746835443, Blast_Score=107, Evalue=2e-24, Organism=Escherichia coli, GI1790162, Length=236, Percent_Identity=29.2372881355932, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1786703, Length=202, Percent_Identity=34.1584158415842, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1788644, Length=241, Percent_Identity=31.9502074688797, Blast_Score=102, Evalue=5e-23, Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1786872, Length=207, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87081709, Length=264, Percent_Identity=26.5151515151515, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1787029, Length=224, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=9e-22, Organism=Escherichia coli, GI87081791, Length=260, Percent_Identity=29.2307692307692, Blast_Score=95, Evalue=7e-21, Organism=Escherichia coli, GI1787105, Length=235, Percent_Identity=32.7659574468085, Blast_Score=92, Evalue=6e-20, Organism=Escherichia coli, GI87082267, Length=239, Percent_Identity=28.8702928870293, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787370, Length=233, Percent_Identity=26.1802575107296, Blast_Score=90, Evalue=3e-19, Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=32.0197044334975, Blast_Score=88, Evalue=9e-19, Organism=Escherichia coli, GI1789873, Length=212, Percent_Identity=31.1320754716981, Blast_Score=88, Evalue=9e-19, Organism=Escherichia coli, GI1786563, Length=210, Percent_Identity=30, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787792, Length=227, Percent_Identity=31.2775330396476, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789864, Length=238, Percent_Identity=23.109243697479, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787164, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1786345, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788450, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI48995001, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1786319, Length=214, Percent_Identity=28.5046728971963, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1790467, Length=233, Percent_Identity=25.7510729613734, Blast_Score=76, Evalue=4e-15, Organism=Escherichia coli, GI1786803, Length=227, Percent_Identity=27.3127753303965, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787143, Length=235, Percent_Identity=31.9148936170213, Blast_Score=75, Evalue=9e-15, Organism=Escherichia coli, GI1786253, Length=222, Percent_Identity=26.1261261261261, Blast_Score=75, Evalue=9e-15, Organism=Escherichia coli, GI1787972, Length=263, Percent_Identity=27.7566539923954, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786654, Length=236, Percent_Identity=28.8135593220339, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI2367384, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1789991, Length=218, Percent_Identity=30.7339449541284, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1788002, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1789586, Length=240, Percent_Identity=24.1666666666667, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790525, Length=231, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786698, Length=216, Percent_Identity=24.537037037037, Blast_Score=64, Evalue=2e-11, Organism=Escherichia coli, GI1787041, Length=248, Percent_Identity=24.5967741935484, Blast_Score=61, Evalue=1e-10, Organism=Caenorhabditis elegans, GI193202349, Length=253, Percent_Identity=32.0158102766798, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193209708, Length=250, Percent_Identity=30.8, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI71984940, Length=254, Percent_Identity=31.1023622047244, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI212646699, Length=240, Percent_Identity=31.25, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI115534520, Length=228, Percent_Identity=28.5087719298246, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17543740, Length=236, Percent_Identity=31.7796610169492, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=31.304347826087, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193208177, Length=235, Percent_Identity=28.936170212766, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17541710, Length=228, Percent_Identity=30.2631578947368, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17533971, Length=241, Percent_Identity=31.1203319502075, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17567265, Length=253, Percent_Identity=30.0395256916996, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI115535101, Length=216, Percent_Identity=31.9444444444444, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17558664, Length=227, Percent_Identity=30.3964757709251, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193211017, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17565938, Length=225, Percent_Identity=29.7777777777778, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193211015, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17567269, Length=228, Percent_Identity=30.2631578947368, Blast_Score=65, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324985, Length=267, Percent_Identity=25.8426966292135, Blast_Score=71, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6322640, Length=239, Percent_Identity=26.3598326359833, Blast_Score=64, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6319856, Length=229, Percent_Identity=26.6375545851528, Blast_Score=63, Evalue=8e-11, Organism=Drosophila melanogaster, GI24641565, Length=227, Percent_Identity=32.5991189427313, Blast_Score=79, Evalue=7e-15, Organism=Drosophila melanogaster, GI24648314, Length=270, Percent_Identity=25.5555555555556, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI281363262, Length=229, Percent_Identity=28.82096069869, Blast_Score=73, Evalue=4e-13, Organism=Drosophila melanogaster, GI24653245, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI85726357, Length=274, Percent_Identity=27.7372262773723, Blast_Score=72, Evalue=7e-13, Organism=Drosophila melanogaster, GI24643674, Length=242, Percent_Identity=22.7272727272727, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI17136662, Length=240, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24659289, Length=242, Percent_Identity=28.5123966942149, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI19920532, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24580930, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 39436; Mature: 39305
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTG CCCCCCEEEEEEEEEEEECCHHHHHHHHCCCEEEEECCEEEEEEECCCCCCHHHHHHHHH MLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITE HHHCCCEEEECCCCCCCCCCEECCCCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH VIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQYSGGMRQRIVIAIALACRPDV HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCHHEEEEEEEEECCCCE LICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIANKVAVMYAGEIVE EEECCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHEEEEEECCHHC YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAM CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCCEEEEECCCEE QIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD EEEHHHCCCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCC >Mature Secondary Structure TKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTG CCCCCEEEEEEEEEEEECCHHHHHHHHCCCEEEEECCEEEEEEECCCCCCHHHHHHHHH MLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITE HHHCCCEEEECCCCCCCCCCEECCCCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH VIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQYSGGMRQRIVIAIALACRPDV HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCHHEEEEEEEEECCCCE LICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIANKVAVMYAGEIVE EEECCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHEEEEEECCHHC YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAM CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCCEEEEECCCEE QIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD EEEHHHCCCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2352474; 11463916 [H]