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The map label for this gene is prmA

Identifier: 225859538

GI number: 225859538

Start: 1702028

End: 1702978

Strand: Reverse

Name: prmA

Synonym: SP70585_1828

Alternate gene names: 225859538

Gene position: 1702978-1702028 (Counterclockwise)

Preceding gene: 225859539

Following gene: 225859537

Centisome position: 77.95

GC content: 48.48

Gene sequence:

>951_bases
ATGGAAACATGGCAAGAGTTAAAAGTTACAGTGAAGCGTGAGGGAGAGGAGTTGGTTTCCAATCTCTTGATTGAGCTGGG
AGCGCAAGGTGTTGCGATTGAAGACAGTCTGGACTATGTGGGAAATGTTGACCGCTTCGGCGAGATTTTCCCAGAGGTCG
AGCAGCAAGAAGAAATCGTAGTGACCGCCTACTACCCTGACACGGTGGATGTGACAGTGGTTGAGGTGGACTTGCAGGCT
CGCATATCAGAATTGACGGATTTTATGGATTTGGGAGAAGTCAAGATGGGGACGACTGCCTTGGCTGAGGAAGACTGGGC
AGACAACTGGAAGAAATACTATGAGCCAGCTCGTATCACTCATGATTTGACCATCGTTCCCTCTTGGACAGACTATGAGG
CGACTGCGGGAGAAAAAATTATCAAGCTAGATCCTGGGATGGCTTTTGGTACTGGGACCCATCCAACTACTAAGATGAGC
CTCTTTGCCTTGGAACAGGTTCTTCGTGGTGGCGAGACAGTGCTAGATGTGGGGACTGGTTCAGGGGTTCTCTCCATTGC
TAGCTCGCTACTTGGTGCCAAGGAAATCTTCGCCTATGACCTAGATGATGTAGCAGTTCGTGTTGCTCAGGAAAATATTG
AGCTCAACCCTGGCATGGAAAATATCCATGTAGCAGCAGGAGACTTGCTTAAGGGAGTTGAGATTGAAGCAGATGTCATC
GTGGCTAATATCTTGGCGGATATTCTCATTCATCTGACGGAGGATGCTTATCGCTTGGTAAAGGATGAAGGCTACCTCAT
CATGAGTGGCATTATCAAGGACAAGTGGGACATGGTGCGCCAGTCGGCTGAGTCAGCTGGATTTTTCCTTGAAACCCATA
TGATTCAAGGGGAATGGAATGCCTGCGTCTTCAAGAAGACCAAGGATATTTCAGGTGTGATTGGAGGCTAG

Upstream 100 bases:

>100_bases
CCTAAACACTGTGCCAAAAAGATAAACTTCTTTTAGACACAAGCGTCTTCAGAGAATTTCCTATTTTGGTTTTGTGTTTT
ACGGGCTTGGTATCTTAATA

Downstream 100 bases:

>100_bases
GATGCAACAGTATTTTGTCAAAGGCAGTGCTATCTCTCCTGTCACCATCGAGGACAAGGAAACCAGTAAGCATATGTTTC
AGGTTATGCGCTTGAAAGAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEVDLQA
RISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG

Sequences:

>Translated_316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEVDLQA
RISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG
>Mature_316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEVDLQA
RISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=261, Percent_Identity=29.8850574712644, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34797; Mature: 34797

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIV
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCEE
VTAYYPDTVDVTVVEVDLQARISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARIT
EEEECCCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTG
EEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
CCHHHHHHHHHCHHHHHEECHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCEEEHHHH
VANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
ACVFKKTKDISGVIGG
EEEEEECCCCCCCCCC
>Mature Secondary Structure
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIV
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCEE
VTAYYPDTVDVTVVEVDLQARISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARIT
EEEECCCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTG
EEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
CCHHHHHHHHHCHHHHHEECHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCEEEHHHH
VANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
ACVFKKTKDISGVIGG
EEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA