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The map label for this gene is frwB [H]

Identifier: 225859375

GI number: 225859375

Start: 1531864

End: 1532175

Strand: Reverse

Name: frwB [H]

Synonym: SP70585_1660

Alternate gene names: 225859375

Gene position: 1532175-1531864 (Counterclockwise)

Preceding gene: 225859376

Following gene: 225859374

Centisome position: 70.13

GC content: 39.42

Gene sequence:

>312_bases
ATGAAAATTGTTGGTGTTGCAGCTTGTACTGTGGGAATTGCCCACACTTATATTGCACAGGAAAAATTAGAGAATGCCGC
AAAGGTAGCTGGACATGTGATTCATGTTGAGACTCAGGGGACAATAGGGGTAGAAAATGAATTGAGTCAAGAGCAGATTG
ATGCAGCGGATGTAGTTATTTTAGCAGTTGATGTTAAGATTTCTGGTATGGAACGCTTTGAGGGTAAAAAGATTATCAAG
GTTCCAACAGAAGTGGCAGTCAAATCTCCCAATAAACTGATTGCTAAAGCTGTTGAGATTGTTACGAAATAA

Upstream 100 bases:

>100_bases
TGGTAATGACGAAGTTGTTGCCAAATTAGTTCGGGCTCAGACATCTGATGATGTGATTGCAGCTTTTTGTTAATAAGAAA
AAATTTTGGAGGGTATCCGT

Downstream 100 bases:

>100_bases
CTGAAAATATTTAAGGAGAAAATATATGTTGAAACACTTAAACTTAAAAGGTCACTTATTGACAGCCATTTCCTATATGA
TTCCAATTGTTTGTGGTGCA

Product: PTS system, IIB component

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGVENELSQEQIDAADVVILAVDVKISGMERFEGKKIIK
VPTEVAVKSPNKLIAKAVEIVTK

Sequences:

>Translated_103_residues
MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGVENELSQEQIDAADVVILAVDVKISGMERFEGKKIIK
VPTEVAVKSPNKLIAKAVEIVTK
>Mature_103_residues
MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGVENELSQEQIDAADVVILAVDVKISGMERFEGKKIIK
VPTEVAVKSPNKLIAKAVEIVTK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=95, Percent_Identity=50.5263157894737, Blast_Score=96, Evalue=4e-22,
Organism=Escherichia coli, GI87082348, Length=98, Percent_Identity=45.9183673469388, Blast_Score=86, Evalue=5e-19,
Organism=Escherichia coli, GI1790390, Length=100, Percent_Identity=34, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1788492, Length=97, Percent_Identity=38.1443298969072, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1786951, Length=98, Percent_Identity=39.7959183673469, Blast_Score=75, Evalue=9e-16,
Organism=Escherichia coli, GI1788730, Length=100, Percent_Identity=34, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 10945; Mature: 10945

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGVENELSQEQIDAADVVI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHCCCCCEEE
LAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVTK
EEEEEEECCCCCCCCCEEEECCCHHEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGVENELSQEQIDAADVVI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHCCCCCEEE
LAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVTK
EEEEEEECCCCCCCCCEEEECCCHHEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]