Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 225859314

GI number: 225859314

Start: 1480326

End: 1481093

Strand: Reverse

Name: dapB

Synonym: SP70585_1598

Alternate gene names: 225859314

Gene position: 1481093-1480326 (Counterclockwise)

Preceding gene: 225859315

Following gene: 225859313

Centisome position: 67.79

GC content: 45.44

Gene sequence:

>768_bases
ATGAGTATTCGAGTAATTATTGCCGGTTTTAAGGGAAAGATGGGTCAAGCTGCTTGCCAGATGGTCTTGACTGATTCAGA
TTTGGACTTGGTAGCAGTTTTGGATCCTTTTGAGTCTGAGTCAGAATGGCAGGGTATTCCTGTTTTCAAGGATAAGGCTG
ATTTAGCTGGTTTTGAAGCGGATGTCTGGGTAGACTTTACTACTCCAGCTGTTGCCTACGAAAATACACGTTTTGCTCTT
GAAAATGGCTTTGCTCCAGTAGTTGGAACGACTGGTTTCACGAGTGAAGAAATTGCAGAGCTAAAAGAATTTTCTCGTGC
CCAAGACTTGGGTGGCCTGATTGCCCCTAACTTTGCCTTGGGTGCTGTCTTACTCATGCAATTTGCGACGCAGGCTGCCA
AATATTTCCCAAATGTGGAGATTATTGAGCTCCATCATGACAAGAAAAAGGATGCTCCGAGTGGAACAGCCATTAAAACA
GCTGAGTTGATGGCAGAGGTTCGAGAGTCAATTCAGCAAGGTGCAGCAGATGAGGAAGAGCTGATTGCTGGTGCTCGTGG
TGCTGACTTTGATGGTATGCGCATCCACTCAGTTCGTTTGCCAGGCTTGGTAGCTCATCAGGAAGTCATCTTTGGCAATC
AGGGAGAAGGGTTGACCCTCCGTCATGACTCCTATGATCGCATCTCCTTCATGACAGGAGTCAATTTGGGAATTAAAGAA
GTTGTCAAGCGTCATGAGCTTGTCTATGGATTAGAACACTTATTATGA

Upstream 100 bases:

>100_bases
GTGAAAAAGATAGTTCTTCCAAGGAGTAGACACTTCTTGATCAGAATTCCTATTTTCACTTTGTGTTCTTACAGGCTTTG
TATCTTAGACAGGAGTAGAG

Downstream 100 bases:

>100_bases
GATTAACGCAAATGCCTTCTGAATTTCAGAAGGCTTTACCAGTATTAGAAAAAATTAAAGAAGCAGGCTTTGAGGCTTAT
TTTGTTGGGGGCTCTGTTCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFAL
ENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
VVKRHELVYGLEHLL

Sequences:

>Translated_255_residues
MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFAL
ENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
VVKRHELVYGLEHLL
>Mature_254_residues
SIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALE
NGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTA
ELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKEV
VKRHELVYGLEHLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27827; Mature: 27696

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEA
CEEEEEEECCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
DVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFAL
EEEEEECCCEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEE
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
HHHCCCCCCCCCEEEEEEECCCEEECHHEEECCCCCCEEEECCCCCCEEEECCCCCCHHH
VVKRHELVYGLEHLL
HHHHHHHHHHHHHHC
>Mature Secondary Structure 
SIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEA
EEEEEEECCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
DVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFAL
EEEEEECCCEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEE
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
HHHCCCCCCCCCEEEEEEECCCEEECHHEEECCCCCCEEEECCCCCCEEEECCCCCCHHH
VVKRHELVYGLEHLL
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA