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The map label for this gene is aspB [H]

Identifier: 225859299

GI number: 225859299

Start: 1458374

End: 1459561

Strand: Reverse

Name: aspB [H]

Synonym: SP70585_1583

Alternate gene names: 225859299

Gene position: 1459561-1458374 (Counterclockwise)

Preceding gene: 225859300

Following gene: 225859298

Centisome position: 66.81

GC content: 46.55

Gene sequence:

>1188_bases
ATGAAATTATCCAACCGTGTTTTAGAAATGGAAGAAAGTGTGACTTTGGCTGCTGGAGCCCGTGCCAAAGCACTGAAGGC
TGAGGGTAGAGATATTTTGTCTCTAACCTTGGGTGAGCCAGATTTCACTACTCCCAAAAATATCCAAGATGCCGCCATTG
CATCGATTCGAGATGGGCGTGCTTCTTTTTATACAGTAACCTCAGGTCTGCCAGAGCTTAAGGCGGCGGTCAATAGCTAC
TTTGAGCGCTTTTACGGCTATTCTGTAGCGTCAAATCAAGTGACAGTCGCTGCGGGAGCCAAATATTCTCTCTATACCTT
CTTTATGGCTGTGGTCAATCCAGGTGATGAAGTCATCATCCCAACCCCATACTGGGTTAGCTATGGAGATCAGGTCAAGA
TGGCAGAAGGCGTTCCCGTCTTTGTTTCTGCTAAGGAAGACAATCACTTTAAGGTGACCGTAGAGCAGTTAGAAGCAGCT
CGCACTGACAAGACCAAGGTTTTGGTGCTGAATTCGCCATCTAATCCCACAGGTATGATTTACACCCGTGAGGAACTCTT
GGCAATTGGAAACTGGGCTGTAGAAAATGATATTCTCATCCTAGCAGATGATATCTATGGCCGCTTGGTTTATAATGGTC
ATGAGTTCACACCGATTTCTAGCCTATCGGAAGCGATTCGCAAGCAAACAGTGGTCATCAATGGTGTGTCTAAAACCTAT
GCCATGACTGGTTGGCGGATTGGTTATGCCGTTGGAGAAGCAGACATTATCGCTGCCATGTCCAAGATTGCAGGTCAAAC
AACTTCGAATCCGTCAGCAGTAGCCCAATATGCAGCAGTTGAGGCTCTATCAGGTGAGCAAGATACTGTAGAAAGCATGC
GTCAGGCCTTTGAAGAACGTCTTAATACCATCTATCCCCTCCTTGCAGAAGTGCCAGGATTTGAAGTGGTCAAACCGCAA
GGGGCCTTCTATCTCTTCCCAAATGTCAAAAAGGCCATGGAGATGAAAGGCTACACGGATGTGACAGACTTTACAACTGT
TATCTTAGAAGAAGCCGAAGTGGCCTTGGTAACAGGAGCTGGATTTGGAGCACCAGAAAATGTCCGCCTCAGCTATGCGA
CAGACCTAGACACGCTTAAAGAAGCAGTCGAACGCTTGAAAGCATTTATGGGTAGTGAGAATGATTGA

Upstream 100 bases:

>100_bases
TTGGTCGTTATCAAGATAAGCCAATCTGGGAAGTCAAGTCAGGATCTGATTTTTATCTAGTAGATTTTGAAACAGGAGCA
TTGGTCAACAAGGAGGGCCT

Downstream 100 bases:

>100_bases
TCATTTTGAGATTAAGGTAAAGGATTTACAAATTTCAGAAGGATTTTATAGGAGTTTTCTCGCTCCTTTGGACTATAAAT
TGGCTTTTAAGACTAGTTCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND

Sequences:

>Translated_395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
>Mature_395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=27.020202020202, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=27.020202020202, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=27.5, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=27.5, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=22.976501305483, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=25.4125412541254, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=24.1192411924119, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=24.1192411924119, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885351, Length=385, Percent_Identity=26.7532467532467, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=26.775956284153, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=26.1096605744125, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=26.8229166666667, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787909, Length=369, Percent_Identity=22.4932249322493, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=422, Percent_Identity=27.4881516587678, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=27.2965879265092, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=409, Percent_Identity=27.8728606356968, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=409, Percent_Identity=27.8728606356968, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=26.4781491002571, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=26.2857142857143, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=344, Percent_Identity=21.5116279069767, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646114, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573067, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573065, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859735, Length=408, Percent_Identity=23.0392156862745, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641770, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641760, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641768, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641766, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641764, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45551451, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43015; Mature: 43015

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGR
CCCCHHHHHHHCCEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCC
ASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVII
CEEEEEECCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCEEE
PTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAARTDKTKVLVLNSPSNPTGMI
CCCCEECCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCEEE
YTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
EEHHHHHEECCEEEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEEECCCHHE
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEER
EECCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTVILEEAEVALVTGA
HHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEC
GFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGR
CCCCHHHHHHHCCEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCC
ASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVII
CEEEEEECCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCEEE
PTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAARTDKTKVLVLNSPSNPTGMI
CCCCEECCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCEEE
YTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
EEHHHHHEECCEEEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEEECCCHHE
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEER
EECCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTVILEEAEVALVTGA
HHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEC
GFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]