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The map label for this gene is trxB

Identifier: 225859219

GI number: 225859219

Start: 1383602

End: 1384513

Strand: Reverse

Name: trxB

Synonym: SP70585_1499

Alternate gene names: 225859219

Gene position: 1384513-1383602 (Counterclockwise)

Preceding gene: 225859220

Following gene: 225859216

Centisome position: 63.37

GC content: 42.0

Gene sequence:

>912_bases
ATGTACGATACTATTATTATCGGTGCTGGACCTGCAGGGATGACTGCGGCCTTGTATGCTGCTCGAAGCAATCTAAAAGT
AGCTTTGATTGAAGGTGGTCTGCCAGGTGGTCAGATGAATAATACATCTGATATCGAAAATTACCCAGGATACGCTAATA
TTAGTGGACCTGAATTGGCTGAAAAGATGTTTGAACCACTTGAAAATCTTGGTGTTGAGCACATTTATGGTTATGTTGAA
AATGTCGAAGACCATGGTGATTTTAAGAAAGTGATGACTGATGACCAAACATATGAAACACGTACAGTTATCGTAGCAAC
TGGTTCTAAACACCGTCCTTTGGGAGTGCTTGGAGAAGAAGAACTGAACAGTCGTGGTGTTTCTTACTGTGCTGTGTGTG
ATGGTGCTTTCTTCCGTGACCAAGATTTATTGGTAGTTGGTGGTGGAGATTCAGCTGTTGAAGAAGCCCTCTTCTTGACT
CGTTTTGCTAAGACTGTTACCATTGTTCACCGTCGTGACCAACTTCGTGCCCAAAAGGTTTTACAAGATCGCGCCTTTGC
GAATGAAAAAATCAGCTTTATCTGGGATTCTGTAGTAAGGGAAATCAAGGGTGAAAACCGAGTAGAATCAGTCGTATTTG
AAAATGTGAAAACAGGTCAAGTGACAGAACAAGCCTTCGGTGGTGTCTTTATCTATGTTGGTTTGGACCCTCTTAGCGAT
TTTGTTAAAGAATTGAATATCCAAGATCAGGCAGGATGGATTGTGACAGATAACCACATGAAAACTGCAGTCGACGGTAT
CTTTGCAGTTGGAGATGTTCGCTTGAAAGACCTTCGCCAAGTAACAACAGCGGTTGGAGATGGAGCTATCGCTGGTCAAG
AAGCCTATAAATTCATTACAGAACATAGTTAA

Upstream 100 bases:

>100_bases
CGGTTATGAGTTTAATTCTTGTTTTCAAGGCATAATCCTTGCGTGATTGACAAGAAAGAGTTAGAATAAAGATAGTTACA
ACAAGAAAGAAGGAATCTAT

Downstream 100 bases:

>100_bases
TCATAAAAAAGTTTCCAATCAGATGACTGGAAACTTTTTTATAGTCTATTTCGGAAAACTTCGTACATGAGAATGGCCGC
AGCAACACTGGCATTAAGGC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVLGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Sequences:

>Translated_303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVLGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS
>Mature_303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVLGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=306, Percent_Identity=35.9477124183007, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=30.5921052631579, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=309, Percent_Identity=38.1877022653722, Blast_Score=198, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=36.4217252396166, Blast_Score=188, Evalue=7e-49,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33164; Mature: 33164

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELA
CCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
EKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVLGEE
HHHHHHHHHCCHHHHHHHHHCCHHCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
ELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKV
HHHCCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHCCCEEEEEECCHHHH
FVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFIT
HHHHCCCCCCCCEEEECCCHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHS
CCC
>Mature Secondary Structure
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELA
CCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
EKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVLGEE
HHHHHHHHHCCHHHHHHHHHCCHHCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
ELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKV
HHHCCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHCCCEEEEEECCHHHH
FVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFIT
HHHHCCCCCCCCEEEECCCHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]