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The map label for this gene is bcrA [H]

Identifier: 225859189

GI number: 225859189

Start: 1356119

End: 1356607

Strand: Reverse

Name: bcrA [H]

Synonym: SP70585_1463

Alternate gene names: 225859189

Gene position: 1356607-1356119 (Counterclockwise)

Preceding gene: 225859192

Following gene: 225859188

Centisome position: 62.1

GC content: 29.65

Gene sequence:

>489_bases
TTGGGTACAAAACAAAAATTAGCTTTGCTTTTAACCCTCGTTACAGAACTTGATATATTGATTTTAGATGAACCGACTAA
TGGTTTAGATATTGAATCATCACAAATAGTTTTAGCGGTTCTAAAAAATTTAGCTTTACATGAAAATGTGGGAATTTTAA
TATCGAGTCATAAATTAGAAGATATTGAAGAAATTTGTGAGAGGGTTCTTTTCTTGGAGAGCGGGCTTTTGACATTTCAA
AAAGTAGGAAAAGATAGTCATAATTTCTTGTTTGAGATAGCTTTTTCATCAGCTACAGATAGAGACATTTTCATTACCAA
ACAAGAATTTGGGGATATTGTTCAGGAAGAGGGACTGAGAATTACTATGTCTGGGAATATTCAAAGTAGTGAGCTTTTTA
AATTTTTTAACGAAAACTCTATTAAAGTAGTTGATTTTAAAACTAAAAAAGAGACGCTTAAAGATATTTATCTAAATCGT
TCAAAATAA

Upstream 100 bases:

>100_bases
GTTAAGTTTTTGTGCTTTGTCGTATACTGTTTCCATAAAAATAGTATAACACTTTTTACAGTTACCGAACAAGTCTAATA
AAAAAGTAAAGACCTATTCT

Downstream 100 bases:

>100_bases
AGGAGGGTTATAATCATGAAATTAAATAAATTTAATTTTCTTAAGGAAAATATAAGAAATTTATATTCATCAGGTGTAAT
ATATCTCGGTTTGCTTATCT

Product: ABC transporter ATP-binding protein - multidrug efflux

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MGTKQKLALLLTLVTELDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKLEDIEEICERVLFLESGLLTFQ
KVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFKTKKETLKDIYLNR
SK

Sequences:

>Translated_162_residues
MGTKQKLALLLTLVTELDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKLEDIEEICERVLFLESGLLTFQ
KVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFKTKKETLKDIYLNR
SK
>Mature_161_residues
GTKQKLALLLTLVTELDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKLEDIEEICERVLFLESGLLTFQK
VGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFKTKKETLKDIYLNRS
K

Specific function: Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic. Probably responsible for energy coupling to the transport system [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 18365; Mature: 18234

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKQKLALLLTLVTELDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKLE
CCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHH
DIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLR
HHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCEE
ITMSGNIQSSELFKFFNENSIKVVDFKTKKETLKDIYLNRSK
EEEECCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GTKQKLALLLTLVTELDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKLE
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHH
DIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLR
HHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCEE
ITMSGNIQSSELFKFFNENSIKVVDFKTKKETLKDIYLNRSK
EEEECCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476193 [H]