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The map label for this gene is aroK

Identifier: 225859137

GI number: 225859137

Start: 1306073

End: 1306549

Strand: Reverse

Name: aroK

Synonym: SP70585_1409

Alternate gene names: 225859137

Gene position: 1306549-1306073 (Counterclockwise)

Preceding gene: 225859138

Following gene: 225859136

Centisome position: 59.8

GC content: 42.56

Gene sequence:

>477_bases
ATGGCTAAGGTGTTATTAGGGTTTATGGGGGCTGGAAAATCGACTATTGCAAGAGGCTTGGACCCTAATTACCTTGATAT
GGATGCTCTGATTGAGAAGCGCCTAGGTATGTCCATTGCGAATTTTTTCGCTGAAAAGGGAGAAGCAGCCTTTCGTCAGG
TAGAATCAGAAGTCCTAGCTGATTTACTACAAACAGACCAAGTCGTGTCAACTGGAGGAGGAGTGGTTATTTCTCAGAGA
AATCGTGACTTACTCAAGACTAATACAGATAACATCTACCTGAAAGCAGATTTTGAAACCCTCTACCAACGTATCGCAGC
TGATAAGGACAATCAGCGACCGCTTTTTCTAAATAATAGCAAGGAAGAACTAGTAGCTATTTTTCAAGAAAGACAGGCTT
GGTATGAGGAAGTGGCTAGTCGGGTTTTGGATGTGACCAAGCTAAGCCCAGAGGAAATTATAGAGGAACTAAGATGA

Upstream 100 bases:

>100_bases
GCAGCCCTCTTGGTTGCAGATGGAGAGGTGGAGCTTGACCGTGCAGAAGCCATCAATACCAGCTATCCTAGTTTCTTTGA
TGATTTGGAGAGCTTGATTC

Downstream 100 bases:

>100_bases
AAATTGCTTATCTAGGTCCCAAGGGATCATTTTCACACCACGTTGTGCAGATAGCTTTTCCTCATGAGGAATTGCAGGCT
TTTGCCAACATTACAGATGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFAEKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQR
NRDLLKTNTDNIYLKADFETLYQRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR

Sequences:

>Translated_158_residues
MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFAEKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQR
NRDLLKTNTDNIYLKADFETLYQRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR
>Mature_157_residues
AKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFAEKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRN
RDLLKTNTDNIYLKADFETLYQRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=160, Percent_Identity=31.25, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI87082255, Length=149, Percent_Identity=38.255033557047, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320332, Length=168, Percent_Identity=27.9761904761905, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 17802; Mature: 17671

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFAEKGEAAFRQVESEVLA
CHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLYQRIAADKDNQRPLFLNNS
HHHHHHHHHHCCCCEEEECCCCCHHHCCCCCEEEEECHHHHHHHHHCCCCCCCCEEECCC
KEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
AKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFAEKGEAAFRQVESEVLA
HHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLYQRIAADKDNQRPLFLNNS
HHHHHHHHHHCCCCEEEECCCCCHHHCCCCCEEEEECHHHHHHHHHCCCCCCCCEEECCC
KEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA