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The map label for this gene is lacD

Identifier: 225858975

GI number: 225858975

Start: 1154118

End: 1155098

Strand: Reverse

Name: lacD

Synonym: SP70585_1240

Alternate gene names: 225858975

Gene position: 1155098-1154118 (Counterclockwise)

Preceding gene: 225858976

Following gene: 225858974

Centisome position: 52.87

GC content: 41.39

Gene sequence:

>981_bases
ATGGCTTTAACAGAACAAAAACGTGTACGCTTAGAAAAACTTTCTGATGAAAATGGTATCATCTCAGCTCTTGCATTTGA
CCAACGTGGTGCTTTGAAACGCCTCATGGCTCAACACCAAACAGAAGAACCAACTGTGGCCCAAATGGAAGAACTTAAAG
TCTTGGTAGCAGATGAATTGACTAAATACGCTTCATCTATGCTTCTTGACCCTGAGTATGGACTTCCAGCAACTAAAGCT
CTTGATGAAAAAGCTGGTCTTCTCCTTGCTTATGAAAAAACAGGTTATGACACAACAAGCACAAAACGCTTGCCAGACTG
CTTGGATGTCTGGTCTGCAAAACGTATTAAAGAAGAAGGTGCAGATGCAGTTAAATTCTTGCTTTACTATGATGTAGATA
GCTCAGACGAACTCAATCAAGAAAAACAAGCCTACATCGAACGCATCGGTTCTGAGTGTGTGGCTGAAGATATCCCATTC
TTCCTTGAAATCCTTGCTTACGATGAAAAAATTGCGGATGCAGGTTCTGTAGAATACGCGAAAGTAAAACCACACAAAGT
TATCGGCGCTATGAAAGTCTTTTCAGACCCACGCTTTAACATTGATGTCTTGAAAGTTGAAGTTCCTGTTAACATTAAAT
ATGTTGAAGGCTTCGCTGAAGGTGAAGTAGTTTATACACGTGAAGAAGCAGCAGCCTTCTTCAAAGCGCAAGATGAAGCA
ACGAACTTGCCATACATCTACTTGAGTGCTGGTGTATCAGCTAAACTCTTCCAAGATACTCTTGTATTTGCTCATGAATC
AGGTGCAAACTTTAACGGAGTTCTTTGTGGCCGTGCTACATGGGCAGGATCAGTTGAAGCTTACATCAAAGATGGTGAAG
CAGCAGCTCGCGAATGGCTTCGCACAACTGGATTTGAAAACATTGATGAGCTCAATAAAGTTCTTCAAACAACAGCGACT
TCATGGAAAGAACGTGTGTAA

Upstream 100 bases:

>100_bases
GTCCTTGGTATGCTCAATGCTCAAGAAAAAATGACTGGTCATGTCAACATGGCCAACTATCAAGCTCTATATGATCAATT
AATAGTAAAAGAGGTATAAA

Downstream 100 bases:

>100_bases
GAAAGTCCTCCTAGTTTAGGAACATGAATCTAAAAAAATTTAAAAAAAGTTGTATGTAAAGGTTTACAAAATAACTTACT
TGTGCTATACTTAAATCACA

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADELTKYASSMLLDPEYGLPATKA
LDEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEA
TNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTAT
SWKERV

Sequences:

>Translated_326_residues
MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADELTKYASSMLLDPEYGLPATKA
LDEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEA
TNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTAT
SWKERV
>Mature_325_residues
ALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADELTKYASSMLLDPEYGLPATKAL
DEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPFF
LEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEAT
NLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATS
WKERV

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915
- InterPro:   IPR005927 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 36386; Mature: 36255

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADEL
CCCCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEG
HHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
ADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPFFLEILAYDEKIADAGSVEYA
CCCEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
KVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEA
ECCCHHHHHHHHHHCCCCCCEEEEEEEECEEEEEEECCCCCCEEEEHHHHHHHHHCCCCC
TNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWL
CCCCEEEEECCCCHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHH
RTTGFENIDELNKVLQTTATSWKERV
HHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADEL
CCCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEG
HHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
ADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPFFLEILAYDEKIADAGSVEYA
CCCEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
KVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEA
ECCCHHHHHHHHHHCCCCCCEEEEEEEECEEEEEEECCCCCCEEEEHHHHHHHHHCCCCC
TNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWL
CCCCEEEEECCCCHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHH
RTTGFENIDELNKVLQTTATSWKERV
HHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]