Click here to switch to the map view.

The map label for this gene is coaA

Identifier: 225858639

GI number: 225858639

Start: 799626

End: 800546

Strand: Reverse

Name: coaA

Synonym: SP70585_0875

Alternate gene names: 225858639

Gene position: 800546-799626 (Counterclockwise)

Preceding gene: 225858651

Following gene: 225858638

Centisome position: 36.64

GC content: 38.44

Gene sequence:

>921_bases
ATGACCAACGAATTTTTACATTTTGAAAAAATCAGCCGCCAGACTTGGCAATCTTTACATCGAAAGACAACACCTCCTTT
GACAGAAGAAGAATTGGAATCTATCAAGAGTTTTAATGACCAAATCAGTCTCCAAGACGTTACAGATATCTATCTCCCCT
TGGCTCATCTGATTCAGATTTACAAGCGAACTAAGGAAGATTTAGCCTTTTCAAAAGGAATTTTCCTCCAACGTGAAAGT
AAATCTCAACCTTTTATTATTGGGGTTTCTGGGAGTGTTGCCGTTGGAAAATCCACAACCAGTCGCCTACTTCAAATCCT
ACTGTCCCGTACGTTTACAGATGCTACGGTTGAGTTGGTTACAACTGATGGTTTTCTCTATCCCAATCAAACCTTGATTG
AGCAGGGGATTTTAAATCGTAAAGGATTTCCTGAAAGCTATAATATGGAAGCTCTTCTCAACTTCTTGGATCGCATCAAA
AATGGACAAGATGTAGATATTCCTGTCTATTCTCATGAAGTTTACGACATCGTACCCGAAGAGAAACAAAGTGTCAAAGC
TGCTGATTTTGTAATTGTTGAGGGAATCAATGTCTTTCAAAATCCACAAAACGATCGTCTCTATATCACTGACTTCTTTG
ACTTTTCCATCTATGTAGATGCTGGAGTGGATGATATTGAAAGTTGGTATCTGGACCGTTTCTTGAAAATGCTGAGTCTA
GCCCAAAACGACCCTGATAGCTACTATTATCGTTTTACTCAGATGCCGATTGGGGAAGTGGAAGCCTTTGCCCATCAGGT
CTGGACCAGTATCAATCTCACAAATCTACAAAATTATATTGAACCAACCAGAAATCGTGCAGAAGTGATTCTTCATAAAA
GCAAGAACCATGAAATCGATGAAATTTACTTAAAAAAATAA

Upstream 100 bases:

>100_bases
ATCACTTATACTATATACCATTGACTTACCACATTCAAGAAACCGCTTTATTTTTTTAGCTTTTTATGGTATGATAGACA
AAATATCTAGGGGAAAACAA

Downstream 100 bases:

>100_bases
TTTTCCCTTGTCAAAACGTAAGTTTTCATATATAATGGTATAGTTAGTAAATATGGAGGTAAGAACATTGGCAAACATTA
AATCAGCTATCAAACGCGCT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRES
KSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIK
NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSL
AQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK

Sequences:

>Translated_306_residues
MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRES
KSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIK
NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSL
AQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
>Mature_305_residues
TNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESK
SQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIKN
GQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLA
QNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=312, Percent_Identity=41.9871794871795, Blast_Score=255, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35528; Mature: 35396

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELV
HHHHHHHHHHHCCEEEEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCCEEEEE
TTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPE
EECCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCC
EKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSL
HHHHHHHHCEEEEECCHHHCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
AQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNLQNYIEPTRNRAEVILHKSKNHEID
HCCCCCHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
EIYLKK
EEEECC
>Mature Secondary Structure 
TNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELV
HHHHHHHHHHHCCEEEEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCCEEEEE
TTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPE
EECCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCC
EKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSL
HHHHHHHHCEEEEECCHHHCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
AQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNLQNYIEPTRNRAEVILHKSKNHEID
HCCCCCHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
EIYLKK
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA