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The map label for this gene is fabA

Identifier: 225853597

GI number: 225853597

Start: 2115031

End: 2115549

Strand: Reverse

Name: fabA

Synonym: BMEA_A2233

Alternate gene names: 225853597

Gene position: 2115549-2115031 (Counterclockwise)

Preceding gene: 225853600

Following gene: 225853596

Centisome position: 99.52

GC content: 62.04

Gene sequence:

>519_bases
ATGGCAGAACAGAAATCGAGCTACGGGTATGAAGAACTCCTGGCCTGCGGCCGCGGCGAGATGTTCGGACCCGGCAACGC
GCAGCTTCCTCTGCCTCCGATGCTGATGATCCACCGCATCACCGAGATCTCTGAAACGGGCGGTGCCTTCGACAAGGGCT
ATATCCGCGCGGAATATGATGTGCGTCCCGATGACTGGTATTTCCCTTGCCACTTTCAGGGCAACCCGATCATGCCGGGC
TGTCTCGGCCTCGACGGCATGTGGCAGCTCACGGGCTTCTTCCTCGGCTGGCTGGGCGAGCCGGGCCGCGGCATGGCCCT
TTCCACCGGCGAGGTAAAGTTCAAGGGCATGGTTCGCCCGCACACCAAGCTTCTGGAATATGGCATCGACTTCAAGCGCG
TGATGCGCGGTCGCCTCGTGCTCGGCACGGCTGACGGCTGGCTGAAGGCCGATGGCGAGCTCATCTATCAGGCAACCGAT
CTGCGGGTCGGCCTGTCCAAGGAAGGCAGCGCGCAATAA

Upstream 100 bases:

>100_bases
GATTTTACTGCCGGAAACAGTCTGTGGTAGGGATGTTCCGGTGAAACTACAACCGGGCCGGATCGCCGGCCGTTACAGAA
TGAACCTCAAGGGAGGCGTA

Downstream 100 bases:

>100_bases
GCTGCCTGAACCACTAAAAATCCACGGGCGCGACTGCAAAAAACGAAGAGTTTTCATGCGGCCGCGCTCAAAACATGCGA
AGATCGCACCTATGTAACCG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYDVRPDDWYFPCHFQGNPIMPG
CLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATD
LRVGLSKEGSAQ

Sequences:

>Translated_172_residues
MAEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYDVRPDDWYFPCHFQGNPIMPG
CLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATD
LRVGLSKEGSAQ
>Mature_171_residues
AEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYDVRPDDWYFPCHFQGNPIMPGC
LGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATDL
RVGLSKEGSAQ

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=57.3099415204678, Blast_Score=210, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_BRUA1 (B2S9G5)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935991.1
- ProteinModelPortal:   B2S9G5
- SMR:   B2S9G5
- GeneID:   6327595
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I20350
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 19086; Mature: 18955

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: ACT_SITE 71-71

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYD
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VRPDDWYFPCHFQGNPIMPGCLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRP
CCCCCEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCC
HTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATDLRVGLSKEGSAQ
HHHHHHHCCCHHHHHCCEEEEECCCCEEECCCEEEEEEECEEEECCCCCCCC
>Mature Secondary Structure 
AEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYD
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VRPDDWYFPCHFQGNPIMPGCLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRP
CCCCCEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCC
HTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATDLRVGLSKEGSAQ
HHHHHHHCCCHHHHHCCEEEEECCCCEEECCCEEEEEEECEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA