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The map label for this gene is nusA [H]

Identifier: 225853588

GI number: 225853588

Start: 2101448

End: 2103061

Strand: Direct

Name: nusA [H]

Synonym: BMEA_A2223

Alternate gene names: 225853588

Gene position: 2101448-2103061 (Clockwise)

Preceding gene: 225853587

Following gene: 225853589

Centisome position: 98.86

GC content: 59.11

Gene sequence:

>1614_bases
ATGGCAGTCAGTGCTAACAGGCTGGAGCTTCTGCAGATCGCCGATGCGGTCGCCCGCGAGAAGTCGATTGACCGTGAGAT
CGTTCTTGCGGCCATGGCCGATGCGATCCAGAAGGCCGCGCGTTCGCGCTATGGCCAGGAAAGCAATATCCGCGCCGACA
TCAATGCGAAGTCCGGCGAGATCAAGTTGCAGCGCCTGCTGGAAGTCGTGGAGAATGTCGAGGATTACGCAACGCAGATT
TCGCTGTTCATGGCGCGCGACCGTAATCCCGATGCGCAGGTTGGCGACTTCATTGCCGATCAGCTTCCGCCGATGGATTT
CGGCCGCATCGCAGCCCAGTCTGCCAAGCAGGTTATTGTGCAGAAAGTGCGCGAAGCCGAACGTGACCGCCAGTATGACG
AATACAAGGATCGCGTTGGCGAAATCGTCAACGGCACCGTCAAGCGTGTCGAATATGGCAATGTGATCGTGGATCTGGGC
CGTGGCGAAGCGATCGTGCGCCGCGACGAACTGATCCCGCGCGAAGCCTTCCGCTATGGCGACCGCATCCGCGCCTATGT
CTATGATGTGCGCCGCGAACAGCGTGGCCCGCAGATTTTCCTGTCGCGCACCCATCCGCAATTCATGGCGAAGCTCTTCA
CCATGGAAGTGCCGGAAATCTATGACGGCATCATCGAGATCAAGTCGGTCGCTCGCGATCCGGGTTCCCGCGCCAAGATC
GCCGTCGTCTCGCGCGATGCGTCCATTGACCCGGTCGGCGCCTGCGTCGGTATGCGCGGCTCCCGCGTTCAGGCTGTTGT
GGCCGAGTTGCAGGGCGAAAAGATCGATATCATTCCGTGGTCGCCGGATGCGGCTTCCTTCATCGTCAACGCGCTTCAGC
CCGCTGAAGTTGCCAAGGTTGTTCTCGATGAAGATGCCGAACGTATTGAAGTTGTCGTTCCGAATGACCAACTATCACTT
GCAATCGGTCGTCGCGGCCAGAACGTCCGCCTCGCCTTGCAGCTTACCGGCTGGGACATCGACATCCTGACGGAAGACGA
GGAATCCGAACGTCGCCATAAGGAATTCGCAGAACGTTCAAACCTGTTCATGGAAGCCCTCAACGTTGACGAAATGGTCG
GTCAGGTTCTTGCCTCCGAAGGTTTCGCCTCCGTTGAAGAACTGGCCTATGTGGATGCAGGCGAAATTTCGTCCATTGAC
GGTTTCGACGAAGACACGGCAGGCGAAATCCAGGATCGCGCCCGCGAATATCTGGAGCGTATCGAAGCCGAGCAGGATGC
CCGCCGCAAGGAACTGGGCGTTGCCGACGAACTGCGCGAACTGCCGGGCATGACCACGGCCATGCTGGTTGCCGTTGGTG
AAGACGGCGTGAAGACCATGGAAGATTTCGCCGGTTATGCGGTGGACGATCTGGTCGGCTGGCGCGAGCGCAAGGATGGC
GACACCATCAACCATAGTGGTGTTCTGACGCCGTTCGACCTTTCGCGTGTCGATGCGGAGCAGATGGTGCTGGCAGCGCG
CTTGAAAGCGGGCTGGATCACCGAAGAGGAACTGGCTGCGGCTTCCGAAGACGTGGAAGCTGAAGAAGCTGGCGACGAGG
AAGCTGCGTCGTAA

Upstream 100 bases:

>100_bases
GCAGAGCCGGAAGACGCCGCATCTACCGAAACGCAAGAGAAGAAATAAGTTTCAGGCATCCGCGCAGGAAAAAGCCGGAT
GCGACACCAAGGAGAGACCT

Downstream 100 bases:

>100_bases
CAATGACGCACCGTAATAGTCTTACGCCTGATAGATTTCAGGCGTAAACTTGGTGCGGCGACAGGCCCTGGATCGCCCCC
TTCGTGGGGAAACAGGGGTT

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MAVSANRLELLQIADAVAREKSIDREIVLAAMADAIQKAARSRYGQESNIRADINAKSGEIKLQRLLEVVENVEDYATQI
SLFMARDRNPDAQVGDFIADQLPPMDFGRIAAQSAKQVIVQKVREAERDRQYDEYKDRVGEIVNGTVKRVEYGNVIVDLG
RGEAIVRRDELIPREAFRYGDRIRAYVYDVRREQRGPQIFLSRTHPQFMAKLFTMEVPEIYDGIIEIKSVARDPGSRAKI
AVVSRDASIDPVGACVGMRGSRVQAVVAELQGEKIDIIPWSPDAASFIVNALQPAEVAKVVLDEDAERIEVVVPNDQLSL
AIGRRGQNVRLALQLTGWDIDILTEDEESERRHKEFAERSNLFMEALNVDEMVGQVLASEGFASVEELAYVDAGEISSID
GFDEDTAGEIQDRAREYLERIEAEQDARRKELGVADELRELPGMTTAMLVAVGEDGVKTMEDFAGYAVDDLVGWRERKDG
DTINHSGVLTPFDLSRVDAEQMVLAARLKAGWITEEELAAASEDVEAEEAGDEEAAS

Sequences:

>Translated_537_residues
MAVSANRLELLQIADAVAREKSIDREIVLAAMADAIQKAARSRYGQESNIRADINAKSGEIKLQRLLEVVENVEDYATQI
SLFMARDRNPDAQVGDFIADQLPPMDFGRIAAQSAKQVIVQKVREAERDRQYDEYKDRVGEIVNGTVKRVEYGNVIVDLG
RGEAIVRRDELIPREAFRYGDRIRAYVYDVRREQRGPQIFLSRTHPQFMAKLFTMEVPEIYDGIIEIKSVARDPGSRAKI
AVVSRDASIDPVGACVGMRGSRVQAVVAELQGEKIDIIPWSPDAASFIVNALQPAEVAKVVLDEDAERIEVVVPNDQLSL
AIGRRGQNVRLALQLTGWDIDILTEDEESERRHKEFAERSNLFMEALNVDEMVGQVLASEGFASVEELAYVDAGEISSID
GFDEDTAGEIQDRAREYLERIEAEQDARRKELGVADELRELPGMTTAMLVAVGEDGVKTMEDFAGYAVDDLVGWRERKDG
DTINHSGVLTPFDLSRVDAEQMVLAARLKAGWITEEELAAASEDVEAEEAGDEEAAS
>Mature_536_residues
AVSANRLELLQIADAVAREKSIDREIVLAAMADAIQKAARSRYGQESNIRADINAKSGEIKLQRLLEVVENVEDYATQIS
LFMARDRNPDAQVGDFIADQLPPMDFGRIAAQSAKQVIVQKVREAERDRQYDEYKDRVGEIVNGTVKRVEYGNVIVDLGR
GEAIVRRDELIPREAFRYGDRIRAYVYDVRREQRGPQIFLSRTHPQFMAKLFTMEVPEIYDGIIEIKSVARDPGSRAKIA
VVSRDASIDPVGACVGMRGSRVQAVVAELQGEKIDIIPWSPDAASFIVNALQPAEVAKVVLDEDAERIEVVVPNDQLSLA
IGRRGQNVRLALQLTGWDIDILTEDEESERRHKEFAERSNLFMEALNVDEMVGQVLASEGFASVEELAYVDAGEISSIDG
FDEDTAGEIQDRAREYLERIEAEQDARRKELGVADELRELPGMTTAMLVAVGEDGVKTMEDFAGYAVDDLVGWRERKDGD
TINHSGVLTPFDLSRVDAEQMVLAARLKAGWITEEELAAASEDVEAEEAGDEEAAS

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=464, Percent_Identity=43.9655172413793, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010995
- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010214
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 59674; Mature: 59542

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSANRLELLQIADAVAREKSIDREIVLAAMADAIQKAARSRYGQESNIRADINAKSGE
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
IKLQRLLEVVENVEDYATQISLFMARDRNPDAQVGDFIADQLPPMDFGRIAAQSAKQVIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QKVREAERDRQYDEYKDRVGEIVNGTVKRVEYGNVIVDLGRGEAIVRRDELIPREAFRYG
HHHHHHHHHCHHHHHHHHHHHHHCCHHHEEEECCEEEECCCCCEEHHHHHCCCHHHHHHH
DRIRAYVYDVRREQRGPQIFLSRTHPQFMAKLFTMEVPEIYDGIIEIKSVARDPGSRAKI
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEE
AVVSRDASIDPVGACVGMRGSRVQAVVAELQGEKIDIIPWSPDAASFIVNALQPAEVAKV
EEEECCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCHHHHHHH
VLDEDAERIEVVVPNDQLSLAIGRRGQNVRLALQLTGWDIDILTEDEESERRHKEFAERS
HHCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCEEEEEECCHHHHHHHHHHHHHH
NLFMEALNVDEMVGQVLASEGFASVEELAYVDAGEISSIDGFDEDTAGEIQDRAREYLER
HHHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IEAEQDARRKELGVADELRELPGMTTAMLVAVGEDGVKTMEDFAGYAVDDLVGWRERKDG
HHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCC
DTINHSGVLTPFDLSRVDAEQMVLAARLKAGWITEEELAAASEDVEAEEAGDEEAAS
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
AVSANRLELLQIADAVAREKSIDREIVLAAMADAIQKAARSRYGQESNIRADINAKSGE
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
IKLQRLLEVVENVEDYATQISLFMARDRNPDAQVGDFIADQLPPMDFGRIAAQSAKQVIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QKVREAERDRQYDEYKDRVGEIVNGTVKRVEYGNVIVDLGRGEAIVRRDELIPREAFRYG
HHHHHHHHHCHHHHHHHHHHHHHCCHHHEEEECCEEEECCCCCEEHHHHHCCCHHHHHHH
DRIRAYVYDVRREQRGPQIFLSRTHPQFMAKLFTMEVPEIYDGIIEIKSVARDPGSRAKI
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEE
AVVSRDASIDPVGACVGMRGSRVQAVVAELQGEKIDIIPWSPDAASFIVNALQPAEVAKV
EEEECCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCHHHHHHH
VLDEDAERIEVVVPNDQLSLAIGRRGQNVRLALQLTGWDIDILTEDEESERRHKEFAERS
HHCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCEEEEEECCHHHHHHHHHHHHHH
NLFMEALNVDEMVGQVLASEGFASVEELAYVDAGEISSIDGFDEDTAGEIQDRAREYLER
HHHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IEAEQDARRKELGVADELRELPGMTTAMLVAVGEDGVKTMEDFAGYAVDDLVGWRERKDG
HHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCC
DTINHSGVLTPFDLSRVDAEQMVLAARLKAGWITEEELAAASEDVEAEEAGDEEAAS
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]