Click here to switch to the map view.

The map label for this gene is 225853555

Identifier: 225853555

GI number: 225853555

Start: 2070883

End: 2071482

Strand: Direct

Name: 225853555

Synonym: BMEA_A2189

Alternate gene names: NA

Gene position: 2070883-2071482 (Clockwise)

Preceding gene: 225853554

Following gene: 225853556

Centisome position: 97.42

GC content: 56.17

Gene sequence:

>600_bases
ATGGCAGGTCAGCTTGGCAGGAAACTCGCCGCGAAGTTCGATGAAGAAATCCGCTTTTTCAAAGGCTGGATAGACGGGCC
AAAAGCAGTCGGTGCGATTCTGCCCACGAGTTCCATCACGGCGCGGCGCATGGCGAGCGTCATCGATGTCAATTCGGGCC
TGCCCGTGCTTGAGTTTGGGCCGGGCACCGGCGTCATCACCAAGGCTATTCTCAAGCATGGCGTGAAACCCGCCGATCTT
TATTCTATTGAATATTCGCACGATTTTGTGGAGCATCTGAACAAGACCTTCCCGGACGTGAACATCATAGAGGGCGATGT
GTTCGATCTCGACACGGCATTGGGCGACAGGAAGGGCCAGAAGTTCGATTGTATCATTTCCGCTGTGCCCATGCTGAATT
TCCCCATGGATCGCCGTGTTGAACTGGTTGAAAGTCTTCTCACCCACATCCCGCACGGGCGTCCCCTGATGCAGATCACC
TATGGACCCTTGCCGCCGGTTCCGGCAGGGCGCGGCAATTACGTGGTCCAGCATTACGACTTCGTCGTGCGCAATGTGCC
GCCTGCTCAGCTCTGGGTCTATCGCAGTCCGCTTGTATAG

Upstream 100 bases:

>100_bases
GCCATGCGGCTCCTTTTTTATTTTGTTTCTAATTCCCGCCTTGCTTATAAACTTCAATGCGGCATAGATTTGTCTAATAA
CGACAATGGGAGCAGCAAGA

Downstream 100 bases:

>100_bases
AGCGGTTCCTGTTTTAACAGAATCCTCGGAACCGCTCTATCTCTTTGTTTTGTCGCATTATCCGACGCAAAACCGCTTCG
CACTTTTGCTGGAAATGCTC

Product: phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase

Products: S-adenosyl-L-homocysteine; phosphatidyl-N-methylethanolamine

Alternate protein names: Ribosomal RNA Adenine Methylase Transferase; Methyltransferase Type; Methyltransferase; Phospholipid N-Methyltransferase-Like Protein; Phospholipid N-Methyltransferase PmtA; Phospholipid N-Methyltransferase Protein; Ribosomal RNA Adenine Methylase Transferase-Like Protein; Adenine Dimethylase; Ribosomal RNA Adenine Dimethylase; Phosphatidylethanolamine N-Methyltransferase; Phospholipid N-Methyltransferase-Like; Ribosomal RNA Adenine Dimethylase Domain Protein; RNA Adenine Methylase Transferase; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Methyltransferase Domain Family Protein; Secreted Protein; Cation-Transporting P-Type ATPase

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAGQLGRKLAAKFDEEIRFFKGWIDGPKAVGAILPTSSITARRMASVIDVNSGLPVLEFGPGTGVITKAILKHGVKPADL
YSIEYSHDFVEHLNKTFPDVNIIEGDVFDLDTALGDRKGQKFDCIISAVPMLNFPMDRRVELVESLLTHIPHGRPLMQIT
YGPLPPVPAGRGNYVVQHYDFVVRNVPPAQLWVYRSPLV

Sequences:

>Translated_199_residues
MAGQLGRKLAAKFDEEIRFFKGWIDGPKAVGAILPTSSITARRMASVIDVNSGLPVLEFGPGTGVITKAILKHGVKPADL
YSIEYSHDFVEHLNKTFPDVNIIEGDVFDLDTALGDRKGQKFDCIISAVPMLNFPMDRRVELVESLLTHIPHGRPLMQIT
YGPLPPVPAGRGNYVVQHYDFVVRNVPPAQLWVYRSPLV
>Mature_198_residues
AGQLGRKLAAKFDEEIRFFKGWIDGPKAVGAILPTSSITARRMASVIDVNSGLPVLEFGPGTGVITKAILKHGVKPADLY
SIEYSHDFVEHLNKTFPDVNIIEGDVFDLDTALGDRKGQKFDCIISAVPMLNFPMDRRVELVESLLTHIPHGRPLMQITY
GPLPPVPAGRGNYVVQHYDFVVRNVPPAQLWVYRSPLV

Specific function: Unknown

COG id: COG3963

COG function: function code I; Phospholipid N-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.17; 2.1.1.71

Molecular weight: Translated: 22019; Mature: 21888

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQLGRKLAAKFDEEIRFFKGWIDGPKAVGAILPTSSITARRMASVIDVNSGLPVLEFG
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEC
PGTGVITKAILKHGVKPADLYSIEYSHDFVEHLNKTFPDVNIIEGDVFDLDTALGDRKGQ
CCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCEEECCCCEEHHHHHCCCCCC
KFDCIISAVPMLNFPMDRRVELVESLLTHIPHGRPLMQITYGPLPPVPAGRGNYVVQHYD
CHHHHEEHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEH
FVVRNVPPAQLWVYRSPLV
HHHHCCCCHHEEEECCCCC
>Mature Secondary Structure 
AGQLGRKLAAKFDEEIRFFKGWIDGPKAVGAILPTSSITARRMASVIDVNSGLPVLEFG
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEC
PGTGVITKAILKHGVKPADLYSIEYSHDFVEHLNKTFPDVNIIEGDVFDLDTALGDRKGQ
CCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCEEECCCCEEHHHHHCCCCCC
KFDCIISAVPMLNFPMDRRVELVESLLTHIPHGRPLMQITYGPLPPVPAGRGNYVVQHYD
CHHHHEEHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEH
FVVRNVPPAQLWVYRSPLV
HHHHCCCCHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; phosphatidylethanolamine

Specific reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA