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The map label for this gene is dnaQ [H]

Identifier: 225853502

GI number: 225853502

Start: 2015149

End: 2015853

Strand: Direct

Name: dnaQ [H]

Synonym: BMEA_A2133

Alternate gene names: 225853502

Gene position: 2015149-2015853 (Clockwise)

Preceding gene: 225853501

Following gene: 225853505

Centisome position: 94.8

GC content: 57.73

Gene sequence:

>705_bases
ATGCGCGAAATCGTTTTTGATACGGAAACCACCGGCCTGGAACGGCTGGAGGACCGCGTGATCGAAATTGGCGGTGTGGA
ACTTGTCAACCGGTTTCCTACAGGCCGCACCTTCCATAAATTCATCAATCCGCAGGGGCGTCAGGTTCATCCCGATGCGC
TCGCCGTTCATGGCATCAGCAACGAACAATTGCTGGACAAACCGGTTTTTGCGGAAATTCTGGACGAGTTTCTGGAATTC
ATCGACGGAGCCAGGCTTGTTGCGCATAACGCCATGTTCGACCTTGGCTTCATCAATGCGGAACTTGCGCGGCTAGACCA
GGCCGAGATCACTTCGGAACATATCGTGGATACGCTGGCGCTCGCCCGTCGCAAACACCCGATAGGGCCGAACTCGCTGG
ATGCGCTCTGCAAGCGTTATGGTATCGACAATTCGCACCGCACCCTGCACGGCGCATTGCTCGACGCGCAGATTCTGGCT
GAAGTCTATATCGAATTGATCGGCGGCAAGCAGACCGCACTTGGCCTGACCATGGAAAGCGGTTCTGCTGGCGGTGACAG
TCGCGGCAATGGCAGCGCACCCGTTGTCCTGGCCGCCCGCCCTCGCCCGTTGCCGCCGCGCATTTCGGATGCGGAACGTG
CGGCCCATGCCGCACTGGTGGAGAAAATGGGCGACAAGGCTGTCTGGAAGAAATATCTATCCTGA

Upstream 100 bases:

>100_bases
GTCAGATTGCCGAAATCATCACCGGATTGAGCGGAAAGCCTGCGGCCGCGACCAGATAGTGGCCTATCCTTATTCAGAAT
ATTTGCGGAGAGGTTCTTCA

Downstream 100 bases:

>100_bases
ATAAAAAAGCCCGGCTGGAACAATTCCAGCCGGGCTTTCCTGCATAATTATTGCGCTATCAGCTCTTCACAGCGGACTTG
GCCTGTTCTTCGGCCATGCG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MREIVFDTETTGLERLEDRVIEIGGVELVNRFPTGRTFHKFINPQGRQVHPDALAVHGISNEQLLDKPVFAEILDEFLEF
IDGARLVAHNAMFDLGFINAELARLDQAEITSEHIVDTLALARRKHPIGPNSLDALCKRYGIDNSHRTLHGALLDAQILA
EVYIELIGGKQTALGLTMESGSAGGDSRGNGSAPVVLAARPRPLPPRISDAERAAHAALVEKMGDKAVWKKYLS

Sequences:

>Translated_234_residues
MREIVFDTETTGLERLEDRVIEIGGVELVNRFPTGRTFHKFINPQGRQVHPDALAVHGISNEQLLDKPVFAEILDEFLEF
IDGARLVAHNAMFDLGFINAELARLDQAEITSEHIVDTLALARRKHPIGPNSLDALCKRYGIDNSHRTLHGALLDAQILA
EVYIELIGGKQTALGLTMESGSAGGDSRGNGSAPVVLAARPRPLPPRISDAERAAHAALVEKMGDKAVWKKYLS
>Mature_234_residues
MREIVFDTETTGLERLEDRVIEIGGVELVNRFPTGRTFHKFINPQGRQVHPDALAVHGISNEQLLDKPVFAEILDEFLEF
IDGARLVAHNAMFDLGFINAELARLDQAEITSEHIVDTLALARRKHPIGPNSLDALCKRYGIDNSHRTLHGALLDAQILA
EVYIELIGGKQTALGLTMESGSAGGDSRGNGSAPVVLAARPRPLPPRISDAERAAHAALVEKMGDKAVWKKYLS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=240, Percent_Identity=47.5, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25615; Mature: 25615

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVFDTETTGLERLEDRVIEIGGVELVNRFPTGRTFHKFINPQGRQVHPDALAVHGIS
CCCEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCCCEECCCCEEEECCC
NEQLLDKPVFAEILDEFLEFIDGARLVAHNAMFDLGFINAELARLDQAEITSEHIVDTLA
CHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LARRKHPIGPNSLDALCKRYGIDNSHRTLHGALLDAQILAEVYIELIGGKQTALGLTMES
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GSAGGDSRGNGSAPVVLAARPRPLPPRISDAERAAHAALVEKMGDKAVWKKYLS
CCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MREIVFDTETTGLERLEDRVIEIGGVELVNRFPTGRTFHKFINPQGRQVHPDALAVHGIS
CCCEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCCCEECCCCEEEECCC
NEQLLDKPVFAEILDEFLEFIDGARLVAHNAMFDLGFINAELARLDQAEITSEHIVDTLA
CHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LARRKHPIGPNSLDALCKRYGIDNSHRTLHGALLDAQILAEVYIELIGGKQTALGLTMES
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GSAGGDSRGNGSAPVVLAARPRPLPPRISDAERAAHAALVEKMGDKAVWKKYLS
CCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]