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The map label for this gene is aroB [H]

Identifier: 225853462

GI number: 225853462

Start: 1971820

End: 1972956

Strand: Reverse

Name: aroB [H]

Synonym: BMEA_A2088

Alternate gene names: 225853462

Gene position: 1972956-1971820 (Counterclockwise)

Preceding gene: 225853463

Following gene: 225853461

Centisome position: 92.81

GC content: 60.42

Gene sequence:

>1137_bases
ATGAATGCGCCCACAACCGTTGCCGATAGTGTTACCGTTCCGGTTTCGCTCGGGGATCGTTCCTACGATATTCTGATCGG
CAAGGGGCTTGTCGAGCGCGCGGGCGAGGAAGTCGCCAAGCGGCTGAAGGGGGTTCGTGTCGCCATCGTCACCGATGAGA
ATGTGGCGGCAGTGCATCTTGAGCGTTTGCAGGCAAGCTTTGCACGGGCCGGTATCGATTCCACGCCGGTGATTGTCGCA
CCTGGAGAAAAATCCAAATCCTTTGCGACGCTTGAAACCGTCACCAACGCCATTCTGGCGGCAAAGCTGGAGCGTGGCGA
TGCGGTGGTGGCGTTGGGCGGTGGCGTGGTGGGCGACCTTTCCGGCTTTGTTGCGGGGATCGTGCGGCGCGGCATGAATT
TCGTGCAAATGCCAACCTCGCTTCTTGCACAGGTCGATTCCTCCGTTGGCGGCAAGACCGGCATTAATACCGCCCATGGC
AAGAACCTCGTTGGTGTCTTTAACCAGCCGCAACTCGTGCTGGCCGATACGCAGGTGCTCGATACGCTGAGCCCGCGTGA
ATTCCGTGCCGGTTATGCGGAAGTCGCAAAATATGGCCTGATCGACCGCCCGGATTTCTTCGCCTGGCTTGAAGCGAACT
GGCAGGAGGTTTTCTCCGGCGGTGCGGCCCGCACAAAGGCTATTGCCGAATCCTGCCGCTCAAAGGCTGCGGTCGTGGCG
CGCGATGAGCGTGAAACCGGCGACCGCGCCCTGCTCAATCTCGGTCATACATTCGGCCATGCGCTGGAAAGCGCAACCGG
CTATGATTCCAGCCGTCTCGTTCATGGCGAAGGGGTCGCGATCGGCATGGCGCTGGCATATCGCTTTTCGGCCCGGATGA
ACCTTGCCGGTATTGAAGCGGCAGAGCGGGTGGAAGCGCATCTGAAAGCTGTCGGCCTGCCGGTTTCGCTGGCCGAGGTG
CCGGGCGGCCTGCCGCCCGCGGAAAAGCTGATGGATTATATCGCGCAGGACAAGAAGGTGACGCGCGGTACGCTGACCTT
CATTCTCACGCATGGCATCGGCCAGTCCTTCATCGCAAAGGACGTACCGCCTGCTGCCGTGCTGGAATTTCTGAAAGAGC
GCCTCGCCATAGCTTAG

Upstream 100 bases:

>100_bases
CCGGATGACGGCCGAAACCTGAAGCGGTCCACGGGCCGTTTTCTTTATTTGTTTCGTGTGTCCGGTCTTTCGTCCACCGG
ATACCAGCAGGAGCTGACCA

Downstream 100 bases:

>100_bases
AGCGGAGATTTGCTGGAACCACTCTAACTATTTGTTCTGTGAAAATTCTAGGGGAACACGGGAATGAGTATCGAGCTTTG
GGTTCTGTGCGGCACTATTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHLERLQASFARAGIDSTPVIVA
PGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDLSGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHG
KNLVGVFNQPQLVLADTQVLDTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVA
RDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEAAERVEAHLKAVGLPVSLAEV
PGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAKDVPPAAVLEFLKERLAIA

Sequences:

>Translated_378_residues
MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHLERLQASFARAGIDSTPVIVA
PGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDLSGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHG
KNLVGVFNQPQLVLADTQVLDTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVA
RDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEAAERVEAHLKAVGLPVSLAEV
PGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAKDVPPAAVLEFLKERLAIA
>Mature_378_residues
MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHLERLQASFARAGIDSTPVIVA
PGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDLSGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHG
KNLVGVFNQPQLVLADTQVLDTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVA
RDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEAAERVEAHLKAVGLPVSLAEV
PGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAKDVPPAAVLEFLKERLAIA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=355, Percent_Identity=44.5070422535211, Blast_Score=256, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=34.1397849462366, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39839; Mature: 39839

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHL
CCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
ERLQASFARAGIDSTPVIVAPGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDL
HHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
SGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHGKNLVGVFNQPQLVLADTQVL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHH
DTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVA
HCCCCHHHHCCHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCEEEE
RDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHH
AERVEAHLKAVGLPVSLAEVPGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAK
HHHHHHHHHHHCCCEEHHHCCCCCCHHHHHHHHHHCCCCCHHHHEEEEEECCCCHHHHHC
DVPPAAVLEFLKERLAIA
CCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHL
CCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
ERLQASFARAGIDSTPVIVAPGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDL
HHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
SGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHGKNLVGVFNQPQLVLADTQVL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHH
DTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVA
HCCCCHHHHCCHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCEEEE
RDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHH
AERVEAHLKAVGLPVSLAEVPGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAK
HHHHHHHHHHHCCCEEHHHCCCCCCHHHHHHHHHHCCCCCHHHHEEEEEECCCCHHHHHC
DVPPAAVLEFLKERLAIA
CCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA