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The map label for this gene is queC

Identifier: 225853408

GI number: 225853408

Start: 1920075

End: 1920773

Strand: Direct

Name: queC

Synonym: BMEA_A2029

Alternate gene names: 225853408

Gene position: 1920075-1920773 (Clockwise)

Preceding gene: 225853403

Following gene: 225853409

Centisome position: 90.33

GC content: 59.51

Gene sequence:

>699_bases
ATGAAAACGCTCGTCATCTGCTCCGGCGGATTGGACTCCGTTTCGCTTGCCCACAAAATGGCGGCGGAACATGAACTCAC
AGGCCTGCTCTCTTTCGATTACGGCCAGCGCCACAAGAAGGAGCTGGACTTCGCCCAGGCCTGCGCAAAAAGGCTTGGCG
TCCCGCATCAGATCATCGATATCCGCACCATTGGCGCAAGCCTGACCGGCTCGGCGCTCACCGATGACGTCGATGTGCCG
GACGGCCACTACGCTGAAGAAACGATGAAAGTCACGGTCGTTCCGAATCGCAACGCCATCATGCTTGCCATCGCCTTCGG
CGTCGCAGCAGCACAGAAAGCCGATGCGGTGGCGCTTGCCGTTCATGGCGGCGATCATTTCATTTATCCCGATTGCCGCC
CCGGCTTCATCGAAGCTTTCCAGACCATGCAGAAACACGCACTGGACGGCTATGCCGATGTGAAACTGCTTGCTCCTTAC
GTCCATGCCACCAAGGCCGACATCGTTGCCGATGGCGCGAAATATCGCACGCCCTTCGAGGCCACATGGTCCTGCTACAA
GGGCGCAGATCGGCATTGCGGGCGCTGCGGCACCTGCGTGGAGCGGCGCGAGGCGTTTCATCTTGCAGGAATAGACGACC
CGACCAGCTATGAGGATGCCGACTTCTGGCGCGCCACCACGCAAAAAAGGAACGCCTGA

Upstream 100 bases:

>100_bases
ACTGCGCCATCCCGTTTCGCGTCGTTTACAAGCCACCGCTCATGCGTTAGGCCGTAAATTATCCGGTCGCAGCCTACCCG
GTCAAAACAAGGATTAGAAT

Downstream 100 bases:

>100_bases
TGTTTCGCATCACCAAGGAATTCCACTTTTCCGCCTCGCACCAGCTCACCGGCCTGCCTGCCGATCACCAATGCGCGCGC
TTGCATGGCCATAACTATAT

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVP
DGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPY
VHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA

Sequences:

>Translated_232_residues
MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVP
DGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPY
VHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
>Mature_232_residues
MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVP
DGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPY
VHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=221, Percent_Identity=31.2217194570136, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_BRUA1 (B2S8M9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935807.1
- ProteinModelPortal:   B2S8M9
- SMR:   B2S8M9
- GeneID:   6326952
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I18510
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK864390
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25256; Mature: 25256

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIID
CCEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHCCHHHHHHHHCCCCEEEEE
IRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALA
EEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEHHHHHHCCCCEEEEE
VHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFE
EECCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHH
ATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
HHHHHHCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIID
CCEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHCCHHHHHHHHCCCCEEEEE
IRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALA
EEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEHHHHHHCCCCEEEEE
VHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFE
EECCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHH
ATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
HHHHHHCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA