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The map label for this gene is rhtC [H]

Identifier: 225853358

GI number: 225853358

Start: 1870731

End: 1871369

Strand: Reverse

Name: rhtC [H]

Synonym: BMEA_A1977

Alternate gene names: 225853358

Gene position: 1871369-1870731 (Counterclockwise)

Preceding gene: 225853359

Following gene: 225853357

Centisome position: 88.04

GC content: 55.56

Gene sequence:

>639_bases
ATGCATCCTTACCTGTTTGAACTTGCATCCCTTATGGCAATCTTCGTTTTTGCCATCGTTTCCCCCGGCGCTGATCTGGC
CATGGTCATCCGGCAATCGCTGCTGCATGGCCGCCGCGAGGCGATCATTACGAGTTTCGGCATCGGTACGGCGCTGATGA
TGCATGTCACCTATACGGTGCTGGGCCTCGGCCTCATCATTTCCAGGTCGATCTATCTGTTCAATATCGTCAAATGGTGC
GGTGTGGCCTATCTGGTCTATATCGGATTCAAGGCGCTGCGTGCCGGCACCACGAAAATCGAGGCGGGTCCGGATTTGAA
GGAGCCGCGCCGGAAACAGGGCTTTGCCAAGGCTTTCGGCCTCGGCTTTGCTGCCAATGCGCTGAACCCCAAGGCCGTTT
TCTTCTTCCTGTCGATTTTCTCCACGGTCGTTCATGTCCATACACCGACCGAAGTGAAACTCGGCTATGGCGTGGTGATG
GCGACCGCATTGATCTCGTGGTTTGTCGGCGTCAGCTTTTTCATGACGACGCCGAAAATGCGCGCGGCTTTCTCGCGCGC
ATCGAAATGGATAGACAGGACGAGCGGCGTGGTATTCATCGCGCTTGGGCTGAAACTTGCCACTGAAAAGGCTATGTAG

Upstream 100 bases:

>100_bases
TCGTCTGGCTCATTAGTCTGGTGGGGCTCGGTATTATGCTTCTGGCTCTGGTTCTGTAATGTCAGCCTGCGCGTGAACGA
CGCGCAATGAAGGAAACGCG

Downstream 100 bases:

>100_bases
GCATTATCTTCGGACGATGAAGATTCGCTGCCGGAAAAGCGCAGCCGGAGCACTCAGGGAGAACCGACGGATGCATACTG
TGAAAAAACTTCTCAACGTG

Product: lysine exporter protein lYSE/YGGA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MHPYLFELASLMAIFVFAIVSPGADLAMVIRQSLLHGRREAIITSFGIGTALMMHVTYTVLGLGLIISRSIYLFNIVKWC
GVAYLVYIGFKALRAGTTKIEAGPDLKEPRRKQGFAKAFGLGFAANALNPKAVFFFLSIFSTVVHVHTPTEVKLGYGVVM
ATALISWFVGVSFFMTTPKMRAAFSRASKWIDRTSGVVFIALGLKLATEKAM

Sequences:

>Translated_212_residues
MHPYLFELASLMAIFVFAIVSPGADLAMVIRQSLLHGRREAIITSFGIGTALMMHVTYTVLGLGLIISRSIYLFNIVKWC
GVAYLVYIGFKALRAGTTKIEAGPDLKEPRRKQGFAKAFGLGFAANALNPKAVFFFLSIFSTVVHVHTPTEVKLGYGVVM
ATALISWFVGVSFFMTTPKMRAAFSRASKWIDRTSGVVFIALGLKLATEKAM
>Mature_212_residues
MHPYLFELASLMAIFVFAIVSPGADLAMVIRQSLLHGRREAIITSFGIGTALMMHVTYTVLGLGLIISRSIYLFNIVKWC
GVAYLVYIGFKALRAGTTKIEAGPDLKEPRRKQGFAKAFGLGFAANALNPKAVFFFLSIFSTVVHVHTPTEVKLGYGVVM
ATALISWFVGVSFFMTTPKMRAAFSRASKWIDRTSGVVFIALGLKLATEKAM

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=201, Percent_Identity=29.8507462686567, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786522, Length=200, Percent_Identity=28.5, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI48994979, Length=130, Percent_Identity=31.5384615384615, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23208; Mature: 23208

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPYLFELASLMAIFVFAIVSPGADLAMVIRQSLLHGRREAIITSFGIGTALMMHVTYTV
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LGLGLIISRSIYLFNIVKWCGVAYLVYIGFKALRAGTTKIEAGPDLKEPRRKQGFAKAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LGFAANALNPKAVFFFLSIFSTVVHVHTPTEVKLGYGVVMATALISWFVGVSFFMTTPKM
CCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHH
RAAFSRASKWIDRTSGVVFIALGLKLATEKAM
HHHHHHHHHHHHHCCCEEEEEECHHHHHHCCC
>Mature Secondary Structure
MHPYLFELASLMAIFVFAIVSPGADLAMVIRQSLLHGRREAIITSFGIGTALMMHVTYTV
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LGLGLIISRSIYLFNIVKWCGVAYLVYIGFKALRAGTTKIEAGPDLKEPRRKQGFAKAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LGFAANALNPKAVFFFLSIFSTVVHVHTPTEVKLGYGVVMATALISWFVGVSFFMTTPKM
CCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHH
RAAFSRASKWIDRTSGVVFIALGLKLATEKAM
HHHHHHHHHHHHHCCCEEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]