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The map label for this gene is talC

Identifier: 225853249

GI number: 225853249

Start: 1752683

End: 1753336

Strand: Direct

Name: talC

Synonym: BMEA_A1855

Alternate gene names: 225853249

Gene position: 1752683-1753336 (Clockwise)

Preceding gene: 225853240

Following gene: 225853252

Centisome position: 82.45

GC content: 56.57

Gene sequence:

>654_bases
ATGAAGTTTTTCGTGGACACTGCGGATGTCAAGGAAATCCGCGAGCTCAACGACCTTGGGCTGGTCGATGGCGTGACCAC
CAACCCGTCCCTCATCCTGAAATCGGGTCGTGATATTATCGAAGTCACCAAGGAAATCTGCAACATCGTCAAGGGCCCGG
TTTCCGCCGAGGTTGCCGCGACCGAATATGAGCAGATGATGAAAGAAGCAGCCGTTATCGCCAGGATCGCTGACAATATC
TGCATCAAGCTGCCTGTCACCCTCGACGGGCTGAAGGCCTGCAAGGCCCTGACGTCAGAAGGCCACAAGGTCAACATGAC
GCTGTGCTTCTCGGCCAATCAGGCGCTTCTGGCTGCCAAGGCCGGTGCAACCTTCATTTCGCCGTTCATTGGCCGTCTGG
ATGATACCGGCATCAACGGCATGGAACTGATTGCCGAAATCCGCACGATTTACGACAATTACGATTTCCGCACCGAAATT
CTTGCCGCTTCGGTTCGTACCGTCAATCACGTCAAGGAAGCAGCACTCATCGGCGCCGATGTCGTGACCGCGCCTCCGGC
AACGCTGAAGGCACTGGTCAAGCATCCGCTGACCGACAAGGGCCTCGAAACCTTCCTCGCCGACTGGGCAAAGACCGGCC
AGAAGATCGCCTGA

Upstream 100 bases:

>100_bases
ACCTTGGCGCGGCTTTGCGCTAAAGAAAAGCCACCTTCCGGGAATTAAATGGTTTTAAATTCCTCAAATCTACCCGCGCT
CATTATGGAGGAACGCTGTT

Downstream 100 bases:

>100_bases
TACGGTCTTTCCATTGAGAGCATTTTCGAGCAAAAAGCGGGCTCAACGGCCCGCTTTTTTATGCCTGCCAGACTTCCGGC
TGAAACAAAAAGGCGATGCC

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKFFVDTADVKEIRELNDLGLVDGVTTNPSLILKSGRDIIEVTKEICNIVKGPVSAEVAATEYEQMMKEAAVIARIADNI
CIKLPVTLDGLKACKALTSEGHKVNMTLCFSANQALLAAKAGATFISPFIGRLDDTGINGMELIAEIRTIYDNYDFRTEI
LAASVRTVNHVKEAALIGADVVTAPPATLKALVKHPLTDKGLETFLADWAKTGQKIA

Sequences:

>Translated_217_residues
MKFFVDTADVKEIRELNDLGLVDGVTTNPSLILKSGRDIIEVTKEICNIVKGPVSAEVAATEYEQMMKEAAVIARIADNI
CIKLPVTLDGLKACKALTSEGHKVNMTLCFSANQALLAAKAGATFISPFIGRLDDTGINGMELIAEIRTIYDNYDFRTEI
LAASVRTVNHVKEAALIGADVVTAPPATLKALVKHPLTDKGLETFLADWAKTGQKIA
>Mature_217_residues
MKFFVDTADVKEIRELNDLGLVDGVTTNPSLILKSGRDIIEVTKEICNIVKGPVSAEVAATEYEQMMKEAAVIARIADNI
CIKLPVTLDGLKACKALTSEGHKVNMTLCFSANQALLAAKAGATFISPFIGRLDDTGINGMELIAEIRTIYDNYDFRTEI
LAASVRTVNHVKEAALIGADVVTAPPATLKALVKHPLTDKGLETFLADWAKTGQKIA

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=177, Percent_Identity=32.2033898305085, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI87081788, Length=211, Percent_Identity=30.3317535545024, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790382, Length=211, Percent_Identity=32.2274881516588, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786189, Length=173, Percent_Identity=33.5260115606936, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788807, Length=242, Percent_Identity=29.7520661157025, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25153750, Length=243, Percent_Identity=30.4526748971193, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25153752, Length=100, Percent_Identity=36, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321480, Length=187, Percent_Identity=31.5508021390374, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323386, Length=199, Percent_Identity=31.6582914572864, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=34.3023255813954, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_BRUA1 (B2S7M9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935650.1
- ProteinModelPortal:   B2S7M9
- SMR:   B2S7M9
- GeneID:   6326790
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I16940
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- ProtClustDB:   PRK01362
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23359; Mature: 23359

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFVDTADVKEIRELNDLGLVDGVTTNPSLILKSGRDIIEVTKEICNIVKGPVSAEVAA
CCEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
TEYEQMMKEAAVIARIADNICIKLPVTLDGLKACKALTSEGHKVNMTLCFSANQALLAAK
HHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
AGATFISPFIGRLDDTGINGMELIAEIRTIYDNYDFRTEILAASVRTVNHVKEAALIGAD
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VVTAPPATLKALVKHPLTDKGLETFLADWAKTGQKIA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFFVDTADVKEIRELNDLGLVDGVTTNPSLILKSGRDIIEVTKEICNIVKGPVSAEVAA
CCEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
TEYEQMMKEAAVIARIADNICIKLPVTLDGLKACKALTSEGHKVNMTLCFSANQALLAAK
HHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
AGATFISPFIGRLDDTGINGMELIAEIRTIYDNYDFRTEILAASVRTVNHVKEAALIGAD
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VVTAPPATLKALVKHPLTDKGLETFLADWAKTGQKIA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA